My recent work focuses on the genetic and functional dissection of complex traits using the mouse genetic toolbox. After developing a collection of interspecific congenic strains which were instrumental in exploring the genetic control […]
My research interests are mainly focused on the structure-function relationships of macromolecules through multidisciplinary approaches. My studies have been concentrated on crucial enzymes belonging to the nucleotide metabolism, in particular nucleoside monophosphate kinases (NMPKs) […]
Born and bred in Alsace, France, I did my PhD at the Institut de Biologie Moleculaire et Cellulaire of Strasbourg, in the laboratory of Prof. Jules Hoffmann under the supervision of Dr. Dominique Ferrandon. […]
I currently lead a junior group in the Virology department of Institut Pasteur. My research interests lie in RNA virus discovery, emergence, transmission, and evolution. Within the group, we use viral genomics to study […]
Philippe J. Sansonetti, MS, MD, is a microbiologist, Professor at the Pasteur Institute and the Collège de France in Paris. He is the Director of the Inserm Unit 1202 and of the Institut Pasteur […]
Intracellular traffic and cell compartmentalization Eukaryotic cells contain extensive internal membranes defining many compartments having each specific functions. However these organelles are constantly moving and reshaping, still retaining their identity. The maintenance of cell […]
Since the beginning of my career, my goal has been to understand the mechanisms of effector immune responses to viruses and the related viral countermeasures. During my thesis, I studied the origin of type […]