Dr. Mouquet earned a BS in Biochemistry, a MS in Biochemistry & Molecular Biology and a PhD in Immunology from the University of Rouen (Normandy, France). He performed his post-doctoral trainee in the laboratory of Michel C. Nussenzweig at the Rockefeller University (2007-2013), where he studied B-cell antibody response to HIV-1, isolated and characterized HIV-1 bNAbs. In 2013, Hugo started his group as a young investigator in the immunology department of the Institut Pasteur, supported by an ERC starting grant award. He currently heads the laboratory of Humoral Immunology at the Institut Pasteur. His lab investigates the humoral responses to pathogens in humans with a focus on HIV-1, Hepatitis viruses and emerging infections, and a dual interest in basic and translational research.
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2020Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models., Cell Host Microbe 2020 Dec; (): .
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2020Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models, Cell Host and Microbe. 2020 Dec.
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2020TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice., PLoS Pathog 2020 Nov; 16(11): e1009025.
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2020Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier., mBio 2020 Oct; 11(5): .
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2020Syncytia formation by SARS-CoV-2 infected cells., EMBO J 2020 Oct; (): e106267.
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2020A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations., Sci Transl Med 2020 09; 12(559): .
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2020Binding mechanisms of therapeutic antibodies to human CD20., Science 2020 Aug; 369(6505): 793-799.
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2020Easy pan-detection of human IgA immunoglobulins., J. Immunol. Methods 2020 Aug; (): 112833.
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2020Broadly neutralizing antibodies potently inhibit cell-to-cell transmission of semen leukocyte-derived SHIV162P3., EBioMedicine 2020 Jun; 57(): 102842.
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2020Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers., J. Exp. Med. 2020 ; 217(10): .
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