Dr. Mouquet earned a BS in Biochemistry, a MS in Biochemistry & Molecular Biology and a PhD in Immunology from the University of Rouen (Normandy, France). He performed his post-doctoral trainee in the laboratory of Michel C. Nussenzweig at the Rockefeller University (2007-2013), where he studied B-cell antibody response to HIV-1, isolated and characterized HIV-1 bNAbs. In 2013, Hugo started his group as a young investigator in the immunology department of the Institut Pasteur, supported by an ERC starting grant award. He currently heads the laboratory of Humoral Immunology at the Institut Pasteur. His lab investigates the humoral responses to pathogens in humans with a focus on HIV-1, Hepatitis viruses and emerging infections, and a dual interest in basic and translational research.
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2022An intranasal lentiviral booster reinforces the waning mRNA vaccine-induced SARS-CoV-2 immunity that it targets to lung mucosa., Mol Ther 2022 Apr; (): .
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2022Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers., Nat Commun 2022 Apr; 13(1): 1944.
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2022Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies., Nat Med 2022 Mar; (): .
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2022Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2., EBioMedicine 2022 Mar; 77(): 103934.
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2022Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller., J Exp Med 2022 Mar; 219(3): .
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2022Advances in human monoclonal antibody therapy for HBV infection., Curr Opin Virol 2022 Feb; 53(): 101205.
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2022Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells., Nat Commun 2022 02; 13(1): 630.
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2022Considerable escape of SARS-CoV-2 Omicron to antibody neutralization., Nature 2022 02; 602(7898): 671-675.
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2021SARS-CoV-2 Alpha, Beta, and Delta variants display enhanced Spike-mediated syncytia formation., EMBO J 2021 12; 40(24): e108944.
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2021NK-B cell cross talk induces CXCR5 expression on natural killer cells., iScience 2021 Oct; 24(10): 103109.
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