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  • Associate Professor
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  • PhD Student
  • Physician
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  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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Scientific Fields
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About

Dr. Mouquet earned a BS in Biochemistry, a MS in Biochemistry & Molecular Biology and a PhD in Immunology from the University of Rouen (Normandy, France). He performed his post-doctoral trainee in the laboratory of Michel C. Nussenzweig at the Rockefeller University (2007-2013), where he studied B-cell antibody response to HIV-1, isolated and characterized HIV-1 bNAbs. In 2013, Hugo started his group as a young investigator in the immunology department of the Institut Pasteur, supported by an ERC starting grant award. He currently heads the laboratory of Humoral Immunology at the Institut Pasteur. His lab investigates the humoral responses to pathogens in humans with a focus on HIV-1, Hepatitis viruses and emerging infections, and a dual interest in basic and translational research.

Projects

Project
Ongoing
7 Members

Archive of the Group for AIDS Research

Lisa Chakrabarti (PI)

This page contains the list of past meetings held by the Group for AIDS Research (Groupe de Réflexion SIDA) of the Pasteur Institute since 2014. The list of previous meetings held since 2002 can […]
Project
Ongoing
13 Members

Group for AIDS Research

Nicoletta Casartelli (PI)

The Group for AIDS Research (Groupe de Réflexion SIDA, GRS) organizes  bimonthly meetings and seminars around an HIV / AIDS research topic. Meetings and seminars are open to all. Meetings are usually held on […]
Project
Ongoing
2 Members

Influence of ART Timing on Mucosal B-cell Responses in HIV-1 Infected Individuals

Hugo Mouquet (PI)

This project in collaboration with Dr Sophie Huë (Service d’Immunologie Biologique, Hôpital Henri Mondor), and funded by Sidaction aims at understanding whether the timing of the antiretroviral therapy (ART) for AIDS treatment can positively influence B-cell / antibody responses […]
Project
Completed
5 Members

Clonal B cells in Cryoglobulinemia Vasculitis with Hepatitits C Infection

Hugo Mouquet (PI)

  Hepatitis C virus (HCV) infection can trigger the development of autoimmune disorders among which, cryobulininemic vasculatitis is the most prevalent. HCV-associated cryobulininemic vasculatitis is mediated by mono-/oligo-clonal IgM cryoglobulins with rheumatoid factor activity, […]
Project
Ongoing
4 Members

Antiviral Properties of Broadly Neutralizing HIV-1 Antibodies

Hugo Mouquet (PI)

Broadly neutralizing HIV-1 antibodies (bNAbs) can develop in rare infected individuals several years after co-evolution with diversifying viruses. In animal models, passive immunotherapy with potent HIV-1 bNAbs has been shown to protect from infection […]
Project
Ongoing
6 Members

ERC-2013-StG HumAntiViruses

Hugo Mouquet (PI)

Human Antibody Responses to Viruses Adaptive immune responses naturally occurring upon infection or induced by vaccination generate high affinity antibodies, and memory B-cell subsets to respond to further antigenic challenges, providing protection against (re-)infections. […]
Project
Ongoing
2 Members

Methodological Approaches for Rapid Antibody Discovery

Hugo Mouquet (PI)

Capture of Single Antigen-Specific B cells to Produce Human Monoclonal Antibodies to Pathogens To achieve our research goals, we are making use of a very efficient method to clone and express immunoglobulins from human […]

Publications

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