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2024Anti-PD-1 therapy triggers Tfh cell-dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes., J Exp Med 2024 Apr; 221(4): .
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2023A major role for CD4+ T cells in driving cytokine release syndrome during CAR T cell therapy., Cell Rep Med 2023 Aug; (): 101161.
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2023Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity., Nat Cancer 2023 May; (): .
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2023Integration of intermittent calcium signals in T cells revealed by temporally patterned optogenetics., iScience 2023 Feb; 26(2): 106068.
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2022Inflammation triggers ILC3 patrolling of the intestinal barrier., Nat Immunol 2022 Aug; (): .
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2022SPICE-Met: profiling and imaging energy metabolism at the single-cell level using a fluorescent reporter mouse., EMBO J 2022 Aug; (): e111528.
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2022Spatiotemporal dynamics of calcium signals during neutrophil cluster formation., Proc Natl Acad Sci U S A 2022 Jul; 119(29): e2203855119.
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2022High resolution microfluidic assay and probabilistic modeling reveal cooperation between T cells in tumor killing., Nat Commun 2022 Jun; 13(1): 3111.
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2021Overexpression of IgG2 in patients resembling IgG4-related disease with normal IgG4., Scand J Immunol 2021 Dec; (): e13126.
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2021Quorum sensing governs collective dendritic cell activation in vivo., EMBO J 2021 Jun; (): e107176.
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2021Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti-tumor activity in vivo., EMBO J 2021 Apr; (): e106658.
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2021A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity., Sci Immunol 2021 Mar; 6(57): .
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2021Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis., Sci Adv 2021 Feb; 7(8): .
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2020Optogenetic manipulation of calcium signals in single T cells in vivo, Nat Commun 2020 Mar;11(1):1143.
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2020Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment., Nat Cancer 2020 Mar; 1(3): 302-314.
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2019Tumor Immunosurveillance and Immunotherapies: A Fresh Look from Intravital Imaging., Trends Immunol 2019 11; 40(11): 1022-1034.
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2019Quorum Sensing by Monocyte-Derived Populations, Front Immunol 2019;10:2140.
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2019Macropinocytosis Overcomes Directional Bias in Dendritic Cells Due to Hydraulic Resistance and Facilitates Space Exploration, Dev. Cell 2019 04;49(2):171-188.e5.
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2019Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity., J Exp Med 2019 05; 216(5): 1038-1049.
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2018Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division, J. Exp. Med. 2018 May;215(5):1481-1492.
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2017Increased TCR signal strength in DN thymocytes promotes development of gut TCRαβ(+)CD8αα(+) intraepithelial lymphocytes., Sci Rep 2017 09; 7(1): 10659.
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2016Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies., Sci Rep 2016 10; 6(): 34382.
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2016The PD-1 Axis Enforces an Anatomical Segregation of CTL Activity that Creates Tumor Niches after Allogeneic Hematopoietic Stem Cell Transplantation, Immunity 2016 Jan;44(1):143-154.
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2015In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity, Nat. Med. 2016 Jan;22(1):64-71.
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2012How many dendritic cells are required to initiate a T-cell response?, Blood 2012 Nov;120(19):3945-8.
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2012Preexisting BCG-specific T cells improve intravesical immunotherapy for bladder cancer, Sci Transl Med 2012 Jun;4(137):137ra72.
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2011Chronic infections capture little attention of the masses, Immunity 2011 May;34(5):699-701.
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2011Selective expansion of merocytic dendritic cells and CD8DCs confers anti-tumour effect of Fms-like tyrosine kinase 3-ligand treatment in vivo, Clin. Exp. Immunol. 2011 Mar;163(3):381-91.
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2010Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells, J. Immunol. 2011 Feb;186(3):1531-7.
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2010Quantifying subcellular distribution of fluorescent fusion proteins in cells migrating within tissues, Immunol. Cell Biol. 2011 May;89(4):549-57.
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2010Prolonged antigen storage endows merocytic dendritic cells with enhanced capacity to prime anti-tumor responses in tumor-bearing mice, J. Immunol. 2010 Sep;185(6):3337-47.
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2010Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes, Proc. Natl. Acad. Sci. U.S.A. 2010 Feb;107(8):3675-80.
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2009Dendritic cells use endocytic pathway for cross-priming class Ib MHC-restricted CD8alphaalpha+TCRalphabeta+ T cells with regulatory properties, J. Immunol. 2009 Jun;182(11):6959-68.
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2007Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes, J. Immunol. 2007 Jul;179(2):1058-67.
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2002TNF-mediated toxicity after massive induction of specific CD8+ T cells following immunization of mice with a tumor-specific peptide, J. Immunol. 2002 Sep;169(6):3053-60.
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