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© Research
Publication : Current opinion in immunology

Cellular orchestration of T cell priming in lymph nodes

Team: Dynamics of Immune Responses
Member: Philippe Bousso
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Current opinion in immunology - 12 Jun 2006

Breart B, Bousso P

Link to Pubmed [PMID] – 16765578

Curr. Opin. Immunol. 2006 Aug;18(4):483-90

Progress made in visualizing T cell responses in vivo and at the single cell level has revealed an unexpected level of complexity in the orchestration of T cell activation in lymph nodes. The choreography that leads to the initiation of a T cell response involves multiple cellular actors, and is intrinsically influenced by their motility and their mode of cell-cell interactions. Recent studies have begun to depict the cellular orchestration of T cell priming and to analyze the way it could influence the outcome of T cell responses.