Timeline
Shahragim Tajbakhsh
Labex Coordinator
20 Mar 2024
project
AFM-Trampolin: Cellular and genetic basis for robustness of cranial myogenic populations (ENCRYPT)
Read more20 Mar 2024
project
ANR-JCJC: Mechanisms defining functional heterogeneity of anatomically distinct myogenic populations (MUSE)
Read more29 Dec 2023
02 Jun 2023
30 May 2023
28 May 2023
publication
A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation
Read more03 May 2022
07 Mar 2022
28 Feb 2022
publication
Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse.
Read more01 Dec 2021
16 Jun 2021
publication
Longitudinal high-resolution imaging through a flexible intravital imaging window
Read more25 Mar 2021
19 Nov 2020
event
DSCB Department seminar: Yohanns Bellaïche, Institut Curie – “How does morphogenesis cope with cell and tissue size?”
Read more17 Nov 2020
publication
Local retinoic acid signaling directs emergence of the extraocular muscle functional unit.
Read more30 Oct 2020
publication
Transcriptome and epigenome diversity and plasticity of muscle stem cells following transplantation.
Read more18 Sep 2020
event
PhD Thesis Defense: “Regulatory roots of cranial muscle diversity: Developmental origins of muscular resilience”
Read more27 Feb 2020
publication
Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation.
Read more25 Sep 2019
publication
Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells.
Read more01 May 2019
publication
High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations
Read more05 Mar 2019
publication
Combined Notch and PDGF Signaling Enhances Migration and Expression of Stem Cell Markers while Inducing Perivascular Cell Features in Muscle Satellite Cells.
Read more24 Jan 2019
01 Jan 2019
26 Nov 2018
publication
Notchless defines a stage-specific requirement for ribosome biogenesis during lineage progression in adult skeletal myogenesis
Read more19 Nov 2018
publication
Unique morphogenetic signatures define mammalian neck muscles and associated connective tissues
Read more29 Oct 2018
publication
RhoA and ERK signalling regulate the expression of the transcription factor Nfix in myogenic cells.
Read more23 Oct 2018
event
Developmental and Cell Stem Biology Department seminar by Professor Igor Adameyko, Developmental Biology and Regenerative Medicine Karolinska Institutet, Stockholm, Sweden
Read more05 Sep 2018
event
PhD Thesis defense: “Implication of DNA damage and repair in viability and differentiation of muscle stem cells”
Read more01 Sep 2018
publication
Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence.
Read more27 Jul 2018
publication
Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis
Read more06 Jun 2018
publication
Correction to: Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells.
Read more08 May 2018
publication
Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors.
Read more01 May 2018
publication
Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem cells in their niche.
Read more06 Apr 2018
15 Mar 2018
publication
Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro
Read more13 Mar 2018
publication
Loss of MyoD and Myf5 in Skeletal Muscle Stem Cells Results in Altered Myogenic Programming and Failed Regeneration.
Read more09 Mar 2018
publication
Small-RNA sequencing identifies dynamic microRNA deregulation during skeletal muscle lineage progression.
Read more01 Jan 2018
01 Jan 2018
publication
Inhibition of the Activin Receptor Type-2B Pathway Restores Regenerative Capacity in Satellite Cell-Depleted Skeletal Muscle.
Read more01 Jan 2018
22 Dec 2017
publication
Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells.
Read more02 Oct 2017
publication
Effect of chemical immobilization of SDF-1α into muscle-derived scaffolds on angiogenesis and muscle progenitor recruitment
Read more12 Aug 2017
12 May 2017
publication
Notch ligands regulate the muscle stem-like state ex vivo but are not sufficient for retaining regenerative capacity
Read more02 May 2017
publication
Quiescence of human muscle stem cells is favored by culture on natural biopolymeric films
Read more06 Apr 2017
publication
lncRNA-Encoded Polypeptide SPAR(s) with mTORC1 to Regulate Skeletal Muscle Regeneration
Read more29 Mar 2017
event
SEMINAR ” Cardiomyocyte behavior and genetic compensation in zebrafish ” by Professor Didier Stainier
Read more28 Mar 2017
09 Mar 2017
13 Feb 2017
publication
Cilia-mediated Hedgehog signaling controls form and function in the mammalian larynx
Read more01 Feb 2017
01 Jan 2017
22 Dec 2016
04 Oct 2016
news
SEMINAR ” Making faces: gene regulatory mechanisms in development, evolution and disease of the human neural crest “
Read more02 Jun 2016
25 Feb 2016
publication
Nfix Regulates Temporal Progression of Muscle Regeneration through Modulation of Myostatin Expression
Read more25 Jan 2016
16 Nov 2015
02 Nov 2015
27 Oct 2015
publication
Numb is required to prevent p53-dependent senescence following skeletal muscle injury
Read more17 Sep 2015
03 Aug 2015
publication
Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy
Read more27 Jul 2015
project
Characterisation of skeletal muscle stem cell properties in distinct physiological states
Read more10 Jul 2015
11 Jun 2015
publication
Chromatin signatures at Notch-regulated enhancers reveal large-scale changes in H3K56ac upon activation
Read more08 Jun 2015
08 Jun 2015
08 Jun 2015
08 Jun 2015
08 Jun 2015
project
Genetic studies reveal differences between somite and cranial mesoderm derived muscles
Read more11 May 2015
01 Jan 2015
01 Dec 2014
publication
Variations in the efficiency of lineage marking and ablation confound distinctions between myogenic cell populations
Read more01 Dec 2014
publication
Bmi1 enhances skeletal muscle regeneration through MT1-mediated oxidative stress protection in a mouse model of dystrophinopathy
Read more13 Nov 2014
publication
Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression
Read more01 Nov 2014
publication
More efficient repair of DNA double-strand breaks in skeletal muscle stem cells compared to their committed progeny.
Read more07 Jul 2014
15 May 2014
publication
Cell adhesion geometry regulates non-random DNA segregation and asymmetric cell fates in mouse skeletal muscle stem cells
Read more01 Mar 2014
publication
Ballroom dancing with stem cells: placement and displacement in the intestinal crypt
Read more24 Jan 2014
01 Jan 2014
22 Jul 2013
13 May 2013
01 May 2013
01 May 2013
25 Apr 2013
publication
Embryonic founders of adult muscle stem cells are primed by the determination gene Mrf4
Read more01 Jan 2013
07 Nov 2012
publication
Cell-autonomous Notch activity maintains the temporal specification potential of skeletal muscle stem cells
Read more05 Nov 2012
publication
Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin
Read more15 Sep 2012
publication
Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity
Read more14 Sep 2012
01 Sep 2012
publication
Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration
Read more24 Feb 2012
publication
Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells
Read more01 Feb 2012
publication
A critical requirement for notch signaling in maintenance of the quiescent skeletal muscle stem cell state
Read more20 Jan 2012
publication
A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division
Read more01 Sep 2011
publication
Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration
Read more19 Aug 2011
publication
Integrated gene regulatory circuits: celebrating the 50(th) anniversary of the operon model
Read more01 Jun 2011
20 Apr 2011
publication
Biophysical stimuli induced by passive movements compensate for lack of skeletal muscle during embryonic skeletogenesis
Read more01 Sep 2010
publication
The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature
Read more01 Aug 2010
01 Jan 2010
publication
Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury
Read more27 Nov 2009
publication
Developing bones are differentially affected by compromised skeletal muscle formation
Read more01 Nov 2009
01 Nov 2009
publication
Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite
Read more01 Oct 2009
01 Sep 2009
22 Aug 2009
publication
Selenoprotein N is dynamically expressed during mouse development and detected early in muscle precursors
Read more01 Jun 2009
publication
Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates
Read more01 Mar 2009
01 Jan 2009
publication
Template DNA-strand co-segregation and asymmetric cell division in skeletal muscle stem cells
Read more01 Jan 2009
25 Nov 2008
01 Oct 2008
02 Oct 2007
11 Sep 2007
publication
A role for the myogenic determination gene Myf5 in adult regenerative myogenesis
Read more01 Jun 2007
07 Feb 2007
publication
Muscle satellite cells and endothelial cells: close neighbors and privileged partners
Read more12 Jan 2007
publication
Intrinsic phenotypic diversity of embryonic and fetal myoblasts is revealed by genome-wide gene expression analysis on purified cells
Read more25 Jun 2006
publication
Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells
Read more01 May 2006
publication
Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.
Read more02 Jan 2006
publication
Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.
Read more01 Sep 2005
publication
Segmenting and tracking fluorescent cells in dynamic 3-D microscopy with coupled active surfaces
Read more15 Jun 2005
publication
Pax3/Pax7 mark a novel population of primitive myogenic cells during development
Read more10 Jun 2005
01 Nov 2004
publication
Analysis of Mlc-lacZ Met mutants highlights the essential function of Met for migratory precursors of hypaxial muscles and reveals a role for Met in the development of hyoid arch-derived facial muscles
Read more23 Sep 2004
15 May 2004
publication
An enhancer directs differential expression of the linked Mrf4 and Myf5 myogenic regulatory genes in the mouse.
Read more01 Aug 2003
publication
Stem cells to tissue: molecular, cellular and anatomical heterogeneity in skeletal muscle
Read more01 Aug 2003
publication
Analysis of a key regulatory region upstream of the Myf5 gene reveals multiple phases of myogenesis, orchestrated at each site by a combination of elements dispersed throughout the locus.
Read more15 Jun 2003
publication
Myf5 and MyoD activation define independent myogenic compartments during embryonic development
Read more15 Nov 2002
publication
Kinetics of myoblast proliferation show that resident satellite cells are competent to fully regenerate skeletal muscle fibers.
Read more01 Jan 2002
09 Jan 1998
01 Oct 1997
04 Apr 1997
publication
Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD.
Read more21 Nov 1996
publication
Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.
Read more01 Jul 1996
publication
Gene targeting the myf-5 locus with nlacZ reveals expression of this myogenic factor in mature skeletal muscle fibres as well as early embryonic muscle.
Read more01 Jun 1996
01 Feb 1995
publication