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© Research
Publication : Current opinion in genetics & development

Stem cells to tissue: molecular, cellular and anatomical heterogeneity in skeletal muscle

Team: Stem Cells And Development
Member: Shahragim Tajbakhsh
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Current opinion in genetics & development - 01 Aug 2003

Tajbakhsh S

Link to Pubmed [PMID] – 12888016

Curr. Opin. Genet. Dev. 2003 Aug;13(4):413-22

Multiple waves of muscle precursors are released from skeletal muscle progenitor cells throughout developmental life, and this process is initiated in precise locations in the embryo. Skeletal muscle diversifies not only after the acquisition of muscle identity, but curiously heterogeneity is observed even in the stem cell population. Recent studies on cell lineage, cell fusion and the nature of post-natal satellite cells have expanded on our fundamental knowledge of the formation of this tissue, and how this tissue is replenished by resident and circulating regenerative stem cells during adult life.