Timeline

Marc Monot
Head of Facility
02 Apr 2024
publication

A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: candidate selection in a preclinical murine model.

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20 Dec 2023
event

Nanopore day

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15 Dec 2023
publication

Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF-κB pathway toward SARS-CoV-2.

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19 May 2023
publication

Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria.

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11 May 2023
publication

The cell wall lipoprotein CD1687 acts as a DNA binding protein during deoxycholate-induced biofilm formation in Clostridioides difficile.

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15 Feb 2023
project

Implementation of an NGS core facility at Institut Pasteur of Tunis: Biomics as capacity building model

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10 Feb 2023
project

PHINDaccess – Implementation of NGS core facility at IP of Tunis

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22 Dec 2022
project

Plasmodium falciparum evolution under artemisinin pressure

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11 Nov 2022
publication

Capturing SARS-CoV-2 from patient samples with low viral abundance: a comparative analysis

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21 Oct 2021
project

Amélioration de la prise en charge des Déficits Immunitaires Primitifs de l’enfant et de l’adulte dans les régions défavorisées du nord-ouest de la Tunisie.

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15 Sep 2021
publication

High‑throughput identification of viral termini and packaging mechanisms in virome datasets using PhageTermVirome

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01 Jul 2021
publication

How Did Institut Pasteur’s NGS Core Facility, Biomics, Manage the Coronavirus Disease 2019 Crisis?

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21 Jun 2021
project

CDPhages – ANR JCJC

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21 Jun 2021
publication

Metabolic adaption to extracellular pyruvate triggers biofilm formation in Clostridioides difficile.

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03 Jun 2021
event

Seminar DPT Microbiology “SYNTAXTM: The first Enzymatic DNA Synthesis System”, Steven Quistad

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25 Feb 2021
project

Supervision of the quality management system ISO 9001

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25 Feb 2021
publication

Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile.

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31 Jul 2020
project

Oncobiomics – THE (heterogenity tumor ecosystem)

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21 Jul 2020
project

Outsourcing high throughput sequencing projects

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30 Oct 2019
tool

Single Cell Transcriptomics, Epigenetic and Genomics (GEX, ATAC, ADT, Multiome)

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28 Sep 2019
project

PHINDaccess

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02 Aug 2019
team

Biomics – Support-Lab

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24 Jun 2019
event

Core4Life Paris 2019 (joint Curie-Pasteur)

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18 Jun 2019
project

Welcome to the Nanopore User Group at Institut Pasteur webpage

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09 May 2019
publication

A microbiota-generated bile salt induces biofilm formation in Clostridium difficile.

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16 Nov 2018
event

Portes ouvertes organisées par la plateforme Biomics

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20 Aug 2018
publication

Clostridium difficile biofilm: remodeling metabolism and cell surface to build a sparse and heterogeneously aggregated architecture

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26 Feb 2018
publication

Discovery of new type I toxin-antitoxin systems adjacent to CRISPR arrays in Clostridium difficile

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01 Jan 2018
publication

Comparative Genomics of Clostridium difficile

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17 Nov 2017
publication

High prevalence and genetic diversity of large phiCD211/phiCDIF1296T-like prophages in Clostridioides difficile

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15 Aug 2017
publication

PhageTerm: a tool for fast and accurate determination of phage termini and packaging mechanism using next-generation sequencing data

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12 May 2017
publication

Comparative transcriptomics analyses reveal the conservation of an ancestral infectious strategy in two bacteriophage genera

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21 Mar 2017
publication

The alternative sigma factor σ plays a crucial role in adaptive strategies of Clostridium difficile during gut infection

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15 Feb 2017
publication

Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291

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14 Feb 2017
software

PhageTerm

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03 Oct 2016
project

Bacteriophage gene expression by RNA-Seq

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23 Sep 2016
project

Prophage elements as a significant source of genetic diversity among epidemic C. difficile 027 strains

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22 Sep 2016
course

Workshop: Bacterial RNAseq

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21 Sep 2016
publication

What’s a SNP between friends: The influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives

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21 Jul 2016
publication

Control of Clostridium difficile Physiopathology in Response to Cysteine Availability

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05 Jul 2016
publication

Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa

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28 Jun 2016
publication

Deciphering Adaptation Strategies of the Epidemic Clostridium difficile 027 Strain during Infection through In Vivo Transcriptional Analysis

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26 Mar 2016
publication

Cpe1786/IscR of Clostridium perfringens represses expression of genes involved in Fe-S cluster biogenesis

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15 Oct 2015
project

Role of ncRNAs in C. difficile physiology and regulatory networks

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14 Oct 2015
project

Biology of anaerobic biofilm formed by Clostridium difficile and their role in  infections

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13 Oct 2015
project

The regulatory network of sporulation and spore morphogenesis in Clostridium difficile

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13 Oct 2015
project

Comparative genomics clostridium strains involved in necrotizing enterocolitis of the preterm newborn

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08 Oct 2015
publication

Clostridium difficile: New Insights into the Evolution of the Pathogenicity Locus

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01 Sep 2015
publication

Function of the CRISPR-Cas System of the Human Pathogen Clostridium difficile

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17 Aug 2015
software

COV2HTML

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11 May 2015
team

Pathogenesis of Bacterial Anaerobes

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01 Apr 2015
publication

Capsules, toxins and AtxA as virulence factors of emerging Bacillus cereus biovar anthracis

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18 Mar 2015
team

Biomics

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06 Feb 2015
project

Genome-wide DNA methylation profiling

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06 Feb 2015
project

Genome-wide genotyping data analysis

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06 Feb 2015
project

Human Genome-Wide Genotyping using High density SNP-microarrays

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03 Feb 2015
publication

Integration of erm(B)-containing elements through large chromosome fragment exchange in Clostridium difficile

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10 Jan 2015
publication

Repressor activity of the RpoS/σS-dependent RNA polymerase requires DNA binding

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01 Dec 2014
publication

Inter- and intraspecies transfer of a Clostridium difficile conjugative transposon conferring resistance to MLSB

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30 Jun 2014
publication

Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile

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09 Jun 2014
publication

Multidisciplinary analysis of a nontoxigenic Clostridium difficile strain with stable resistance to metronidazole

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19 May 2014
publication

The flagellin FliC of Clostridium difficile is responsible for pleiotropic gene regulation during in vivo infection

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08 May 2014
publication

Expanding the RpoS/σS-network by RNA sequencing and identification of σS-controlled small RNAs in Salmonella

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10 Feb 2014
publication

COV2HTML: a visualization and analysis tool of bacterial next generation sequencing (NGS) data for postgenomics life scientists

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23 Jan 2014
publication

Sequence similarity of Clostridium difficile strains by analysis of conserved genes and genome content is reflected by their ribotype affiliation

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16 Dec 2013
publication

Characterization of the SigD regulon of C. difficile and its positive control of toxin production through the regulation of tcdR

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03 Oct 2013
publication

The spore differentiation pathway in the enteric pathogen Clostridium difficile

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03 Oct 2013
publication

Genome-wide analysis of cell type-specific gene transcription during spore formation in Clostridium difficile

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16 Sep 2013
project

Control of toxin synthesis and secretion in Clostridium difficile

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29 Jul 2013
publication

Adaptive strategies and pathogenesis of Clostridium difficile from in vivo transcriptomics

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09 May 2013
publication

Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile

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18 Sep 2012
publication

Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile

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13 May 2011
publication

The key sigma factor of transition phase, SigH, controls sporulation, metabolism, and virulence factor expression in Clostridium difficile

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13 Apr 2011
publication

Rapid diagnosis of Clostridium difficile infection by multiplex real-time PCR

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28 Mar 2011
publication

Molecular drug susceptibility testing and genotyping of Mycobacterium leprae strains from South America

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24 Feb 2011
publication

Reannotation of the genome sequence of Clostridium difficile strain 630

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07 Sep 2010
publication

Global regulation of gene expression in response to cysteine availability in Clostridium perfringens

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07 Jan 2010
publication

Effect of serial subculturing on the genetic composition and cytotoxic activity of Mycobacterium tuberculosis

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01 Nov 2009
publication

Comparative genomic and phylogeographic analysis of Mycobacterium leprae

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17 Aug 2009
project

Pathogenomic analysis of high potential virulent strains of C. difficile

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06 Jan 2009
publication

Mycobasterium leprae genotype amplified from an archeological case of lepromatous leprosy in Central Asia.

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21 May 2008
publication

Are variable-number tandem repeats appropriate for genotyping Mycobacterium leprae?

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01 Feb 2008
publication

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

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26 May 2006
publication

Towards an immunodiagnostic test for leprosy

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01 Jan 2006
publication

Antigen discovery: a postgenomic approach to leprosy diagnosis

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13 May 2005
publication

On the origin of leprosy

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