Timeline
Marc Monot
Head of Facility
02 Apr 2024
publication
A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: candidate selection in a preclinical murine model.
Read more20 Dec 2023
15 Dec 2023
publication
Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF-κB pathway toward SARS-CoV-2.
Read more19 May 2023
publication
Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria.
Read more11 May 2023
publication
The cell wall lipoprotein CD1687 acts as a DNA binding protein during deoxycholate-induced biofilm formation in Clostridioides difficile.
Read more15 Feb 2023
project
Implementation of an NGS core facility at Institut Pasteur of Tunis: Biomics as capacity building model
Read more10 Feb 2023
22 Dec 2022
11 Nov 2022
publication
Capturing SARS-CoV-2 from patient samples with low viral abundance: a comparative analysis
Read more21 Oct 2021
project
Amélioration de la prise en charge des Déficits Immunitaires Primitifs de l’enfant et de l’adulte dans les régions défavorisées du nord-ouest de la Tunisie.
Read more15 Sep 2021
publication
High‑throughput identification of viral termini and packaging mechanisms in virome datasets using PhageTermVirome
Read more01 Jul 2021
publication
How Did Institut Pasteur’s NGS Core Facility, Biomics, Manage the Coronavirus Disease 2019 Crisis?
Read more21 Jun 2021
21 Jun 2021
publication
Metabolic adaption to extracellular pyruvate triggers biofilm formation in Clostridioides difficile.
Read more03 Jun 2021
event
Seminar DPT Microbiology “SYNTAXTM: The first Enzymatic DNA Synthesis System”, Steven Quistad
Read more25 Feb 2021
25 Feb 2021
publication
Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile.
Read more31 Jul 2020
21 Jul 2020
30 Oct 2019
28 Sep 2019
02 Aug 2019
24 Jun 2019
18 Jun 2019
09 May 2019
publication
A microbiota-generated bile salt induces biofilm formation in Clostridium difficile.
Read more16 Nov 2018
20 Aug 2018
publication
Clostridium difficile biofilm: remodeling metabolism and cell surface to build a sparse and heterogeneously aggregated architecture
Read more26 Feb 2018
publication
Discovery of new type I toxin-antitoxin systems adjacent to CRISPR arrays in Clostridium difficile
Read more01 Jan 2018
17 Nov 2017
publication
High prevalence and genetic diversity of large phiCD211/phiCDIF1296T-like prophages in Clostridioides difficile
Read more15 Aug 2017
publication
PhageTerm: a tool for fast and accurate determination of phage termini and packaging mechanism using next-generation sequencing data
Read more12 May 2017
publication
Comparative transcriptomics analyses reveal the conservation of an ancestral infectious strategy in two bacteriophage genera
Read more21 Mar 2017
publication
The alternative sigma factor σ plays a crucial role in adaptive strategies of Clostridium difficile during gut infection
Read more15 Feb 2017
publication
Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291
Read more14 Feb 2017
03 Oct 2016
23 Sep 2016
project
Prophage elements as a significant source of genetic diversity among epidemic C. difficile 027 strains
Read more22 Sep 2016
21 Sep 2016
publication
What’s a SNP between friends: The influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives
Read more21 Jul 2016
publication
Control of Clostridium difficile Physiopathology in Response to Cysteine Availability
Read more05 Jul 2016
publication
Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa
Read more28 Jun 2016
publication
Deciphering Adaptation Strategies of the Epidemic Clostridium difficile 027 Strain during Infection through In Vivo Transcriptional Analysis
Read more26 Mar 2016
publication
Cpe1786/IscR of Clostridium perfringens represses expression of genes involved in Fe-S cluster biogenesis
Read more15 Oct 2015
14 Oct 2015
project
Biology of anaerobic biofilm formed by Clostridium difficile and their role in infections
Read more13 Oct 2015
project
The regulatory network of sporulation and spore morphogenesis in Clostridium difficile
Read more13 Oct 2015
project
Comparative genomics clostridium strains involved in necrotizing enterocolitis of the preterm newborn
Read more08 Oct 2015
publication
Clostridium difficile: New Insights into the Evolution of the Pathogenicity Locus
Read more01 Sep 2015
17 Aug 2015
11 May 2015
01 Apr 2015
publication
Capsules, toxins and AtxA as virulence factors of emerging Bacillus cereus biovar anthracis
Read more18 Mar 2015
06 Feb 2015
06 Feb 2015
06 Feb 2015
03 Feb 2015
publication
Integration of erm(B)-containing elements through large chromosome fragment exchange in Clostridium difficile
Read more10 Jan 2015
publication
Repressor activity of the RpoS/σS-dependent RNA polymerase requires DNA binding
Read more01 Dec 2014
publication
Inter- and intraspecies transfer of a Clostridium difficile conjugative transposon conferring resistance to MLSB
Read more30 Jun 2014
publication
Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile
Read more09 Jun 2014
publication
Multidisciplinary analysis of a nontoxigenic Clostridium difficile strain with stable resistance to metronidazole
Read more19 May 2014
publication
The flagellin FliC of Clostridium difficile is responsible for pleiotropic gene regulation during in vivo infection
Read more08 May 2014
publication
Expanding the RpoS/σS-network by RNA sequencing and identification of σS-controlled small RNAs in Salmonella
Read more10 Feb 2014
publication
COV2HTML: a visualization and analysis tool of bacterial next generation sequencing (NGS) data for postgenomics life scientists
Read more23 Jan 2014
publication
Sequence similarity of Clostridium difficile strains by analysis of conserved genes and genome content is reflected by their ribotype affiliation
Read more16 Dec 2013
publication
Characterization of the SigD regulon of C. difficile and its positive control of toxin production through the regulation of tcdR
Read more03 Oct 2013
publication
The spore differentiation pathway in the enteric pathogen Clostridium difficile
Read more03 Oct 2013
publication
Genome-wide analysis of cell type-specific gene transcription during spore formation in Clostridium difficile
Read more16 Sep 2013
29 Jul 2013
publication
Adaptive strategies and pathogenesis of Clostridium difficile from in vivo transcriptomics
Read more09 May 2013
publication
Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile
Read more18 Sep 2012
publication
Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile
Read more13 May 2011
publication
The key sigma factor of transition phase, SigH, controls sporulation, metabolism, and virulence factor expression in Clostridium difficile
Read more13 Apr 2011
28 Mar 2011
publication
Molecular drug susceptibility testing and genotyping of Mycobacterium leprae strains from South America
Read more24 Feb 2011
07 Sep 2010
publication
Global regulation of gene expression in response to cysteine availability in Clostridium perfringens
Read more07 Jan 2010
publication
Effect of serial subculturing on the genetic composition and cytotoxic activity of Mycobacterium tuberculosis
Read more01 Nov 2009
17 Aug 2009
06 Jan 2009
publication
Mycobasterium leprae genotype amplified from an archeological case of lepromatous leprosy in Central Asia.
Read more21 May 2008
publication
Are variable-number tandem repeats appropriate for genotyping Mycobacterium leprae?
Read more01 Feb 2008
publication
Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP
Read more26 May 2006
01 Jan 2006
13 May 2005