Ligne de temps
Marc Monot
Responsable de Plateforme
02 avr. 2024
publication
A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: candidate selection in a preclinical murine model.
Lire plus20 déc. 2023
15 déc. 2023
publication
Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF-κB pathway toward SARS-CoV-2.
Lire plus19 mai 2023
publication
Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria.
Lire plus11 mai 2023
publication
The cell wall lipoprotein CD1687 acts as a DNA binding protein during deoxycholate-induced biofilm formation in Clostridioides difficile.
Lire plus15 févr. 2023
project
Implementation of an NGS core facility at Institut Pasteur of Tunis: Biomics as capacity building model
Lire plus10 févr. 2023
22 déc. 2022
11 nov. 2022
publication
Capturing SARS-CoV-2 from patient samples with low viral abundance: a comparative analysis
Lire plus21 oct. 2021
project
Amélioration de la prise en charge des Déficits Immunitaires Primitifs de l’enfant et de l’adulte dans les régions défavorisées du nord-ouest de la Tunisie.
Lire plus15 sept. 2021
publication
High‑throughput identification of viral termini and packaging mechanisms in virome datasets using PhageTermVirome
Lire plus01 juil. 2021
publication
How Did Institut Pasteur’s NGS Core Facility, Biomics, Manage the Coronavirus Disease 2019 Crisis?
Lire plus21 juin 2021
21 juin 2021
publication
Metabolic adaption to extracellular pyruvate triggers biofilm formation in Clostridioides difficile.
Lire plus03 juin 2021
event
Seminar DPT Microbiology “SYNTAXTM: The first Enzymatic DNA Synthesis System”, Steven Quistad
Lire plus25 févr. 2021
25 févr. 2021
publication
Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile.
Lire plus31 juil. 2020
21 juil. 2020
30 oct. 2019
28 sept. 2019
02 août 2019
24 juin 2019
18 juin 2019
09 mai 2019
publication
A microbiota-generated bile salt induces biofilm formation in Clostridium difficile.
Lire plus16 nov. 2018
20 août 2018
publication
Clostridium difficile biofilm: remodeling metabolism and cell surface to build a sparse and heterogeneously aggregated architecture
Lire plus26 févr. 2018
publication
Discovery of new type I toxin-antitoxin systems adjacent to CRISPR arrays in Clostridium difficile
Lire plus01 janv. 2018
17 nov. 2017
publication
High prevalence and genetic diversity of large phiCD211/phiCDIF1296T-like prophages in Clostridioides difficile
Lire plus15 août 2017
publication
PhageTerm: a tool for fast and accurate determination of phage termini and packaging mechanism using next-generation sequencing data
Lire plus12 mai 2017
publication
Comparative transcriptomics analyses reveal the conservation of an ancestral infectious strategy in two bacteriophage genera
Lire plus21 mars 2017
publication
The alternative sigma factor σ plays a crucial role in adaptive strategies of Clostridium difficile during gut infection
Lire plus15 févr. 2017
publication
Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291
Lire plus14 févr. 2017
03 oct. 2016
23 sept. 2016
project
Prophage elements as a significant source of genetic diversity among epidemic C. difficile 027 strains
Lire plus22 sept. 2016
21 sept. 2016
publication
What’s a SNP between friends: The influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives
Lire plus21 juil. 2016
publication
Control of Clostridium difficile Physiopathology in Response to Cysteine Availability
Lire plus05 juil. 2016
publication
Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa
Lire plus28 juin 2016
publication
Deciphering Adaptation Strategies of the Epidemic Clostridium difficile 027 Strain during Infection through In Vivo Transcriptional Analysis
Lire plus26 mars 2016
publication
Cpe1786/IscR of Clostridium perfringens represses expression of genes involved in Fe-S cluster biogenesis
Lire plus15 oct. 2015
14 oct. 2015
project
Biology of anaerobic biofilm formed by Clostridium difficile and their role in infections
Lire plus13 oct. 2015
project
The regulatory network of sporulation and spore morphogenesis in Clostridium difficile
Lire plus13 oct. 2015
project
Comparative genomics clostridium strains involved in necrotizing enterocolitis of the preterm newborn
Lire plus08 oct. 2015
publication
Clostridium difficile: New Insights into the Evolution of the Pathogenicity Locus
Lire plus01 sept. 2015
17 août 2015
11 mai 2015
01 avr. 2015
publication
Capsules, toxins and AtxA as virulence factors of emerging Bacillus cereus biovar anthracis
Lire plus18 mars 2015
06 févr. 2015
06 févr. 2015
06 févr. 2015
03 févr. 2015
publication
Integration of erm(B)-containing elements through large chromosome fragment exchange in Clostridium difficile
Lire plus10 janv. 2015
publication
Repressor activity of the RpoS/σS-dependent RNA polymerase requires DNA binding
Lire plus01 déc. 2014
publication
Inter- and intraspecies transfer of a Clostridium difficile conjugative transposon conferring resistance to MLSB
Lire plus30 juin 2014
publication
Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile
Lire plus09 juin 2014
publication
Multidisciplinary analysis of a nontoxigenic Clostridium difficile strain with stable resistance to metronidazole
Lire plus19 mai 2014
publication
The flagellin FliC of Clostridium difficile is responsible for pleiotropic gene regulation during in vivo infection
Lire plus08 mai 2014
publication
Expanding the RpoS/σS-network by RNA sequencing and identification of σS-controlled small RNAs in Salmonella
Lire plus10 févr. 2014
publication
COV2HTML: a visualization and analysis tool of bacterial next generation sequencing (NGS) data for postgenomics life scientists
Lire plus23 janv. 2014
publication
Sequence similarity of Clostridium difficile strains by analysis of conserved genes and genome content is reflected by their ribotype affiliation
Lire plus16 déc. 2013
publication
Characterization of the SigD regulon of C. difficile and its positive control of toxin production through the regulation of tcdR
Lire plus03 oct. 2013
publication
The spore differentiation pathway in the enteric pathogen Clostridium difficile
Lire plus03 oct. 2013
publication
Genome-wide analysis of cell type-specific gene transcription during spore formation in Clostridium difficile
Lire plus16 sept. 2013
29 juil. 2013
publication
Adaptive strategies and pathogenesis of Clostridium difficile from in vivo transcriptomics
Lire plus09 mai 2013
publication
Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile
Lire plus18 sept. 2012
publication
Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile
Lire plus13 mai 2011
publication
The key sigma factor of transition phase, SigH, controls sporulation, metabolism, and virulence factor expression in Clostridium difficile
Lire plus13 avr. 2011
28 mars 2011
publication
Molecular drug susceptibility testing and genotyping of Mycobacterium leprae strains from South America
Lire plus24 févr. 2011
07 sept. 2010
publication
Global regulation of gene expression in response to cysteine availability in Clostridium perfringens
Lire plus07 janv. 2010
publication
Effect of serial subculturing on the genetic composition and cytotoxic activity of Mycobacterium tuberculosis
Lire plus01 nov. 2009
17 août 2009
06 janv. 2009
publication
Mycobasterium leprae genotype amplified from an archeological case of lepromatous leprosy in Central Asia.
Lire plus21 mai 2008
publication
Are variable-number tandem repeats appropriate for genotyping Mycobacterium leprae?
Lire plus01 févr. 2008
publication
Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP
Lire plus26 mai 2006
01 janv. 2006
13 mai 2005