I have been the manager of the Pasteur Proteomics facility since September 2013. I am responsible for the operations of the proteomics platform and the coordination of the different ongoing projects. I did my PhD research in the group of Dr. Bernard Monsarrat and Dr. Odile Schiltz at the Institute of Pharmacology and Structural Biology (IPBS, University Paul Sabatier, UPS, also known as Toulouse III, France). As part of my PhD work, I used high-resolution mass spectrometers, including the LTQ-Orbitrap, in combination with various quantitative proteomic approaches. My focus was on stable isotope labelling strategies (SILAC and ICAT) to study the proteasome inhibitor effect in acute myeloid leukaemia cells. I then moved to the Institute of Molecular Systems Biology in Eidgenössische Technische Hochschule (ETH Zürich) as a post-doctoral fellow in the group of Professor Ruedi Aebersold. I worked on multiple projects using mass spectrometry to assess changes in protein abundance and posttranslational modifications, e.g., ubiquitin, SUMO, and chlorination of proteins using discovery-driven and targeted mass spectrometry. During this time, I utilised the new data independent acquisition mode developed in Ruedi Aebersold Lab, namely SWATH-MS.
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2024Profiling Cullin4-E3 ligases interactomes and their rewiring in influenza A virus infection., Mol Cell Proteomics 2024 Oct; (): 100856.
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2024Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators, eLife, 2024, 13, pp.RP99172. ⟨10.7554/eLife.99172⟩.
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2024Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated to queuosine tRNA modification, Elife.
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2024The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication., Nucleic Acids Res 2024 Apr; (): .
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2023Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis., Nat Commun 2023 Dec; 14(1): 8474.
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2023Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease., Nat Commun 2023 Dec; 14(1): 8072.
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2023Tunnelling nanotube formation is driven by Eps8/IRSp53‐dependent linear actin polymerization, EMBO Journal, 2023, pp.e113761. ⟨10.15252/embj.2023113761⟩.
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2023Encystation and Stress Responses under the Control of Ubiquitin-like Proteins in Pathogenic Amoebae, Microorganisms.
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2023The cell wall lipoprotein CD1687 acts as a DNA binding protein during deoxycholate-induced biofilm formation in Clostridioides difficile., NPJ Biofilms Microbiomes 2023 May; 9(1): 24.
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2023Biological differences between FIM2 and FIM3 fimbriae of Bordetella pertussis: not just the serotype, Microbes and Infection, 2023, pp.105152. ⟨10.1016/j.micinf.2023.105152⟩.
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