Timeline

Francina Langa Vives
Head of Structure
04 Oct 2018
publication

A Human Polymorphism in CHRNA5 Is Linked to Relapse to Nicotine Seeking in Transgenic Rats

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17 Dec 2017
publication

Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia

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14 Dec 2017
publication

MITF – A controls branching morphogenesis and nephron endowment

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26 Sep 2016
publication

The circadian gene Arntl2 on distal mouse chromosome 6 controls thymocyte apoptosis

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30 Aug 2016
publication

The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination

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22 Apr 2016
publication

Generation of a Double KO Mouse by Simultaneous Targeting of the Neighboring Genes Tmem176a and Tmem176b Using CRISPR/Cas9: Key Steps from Design to Genotyping

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08 Jan 2016
publication

Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts

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04 Nov 2015
publication

Fine-tuning the onset of myogenesis by homeobox proteins that interact with the Myf5 limb enhancer

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17 Feb 2015
team

Mouse Genetics Engineering

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06 Feb 2015
project

Rat transgenesis

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26 Jan 2015
project

Genome modifications by CRISPR/cas9 system

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26 Jan 2015
project

Gene editing by specific nucleases (zinc finger nucleases-zfns, tale nucleases, CRISPR/Cas9 system)

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26 Jan 2015
project

Microinjection of “External” Mutant ES Cells And Subsequently Germ-Line Chimera Generation

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26 Jan 2015
project

Lentiviral Transgenesis

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26 Jan 2015
project

Targeted Transgenesis By Homologous Recombination In Embryonic Stem (ES) Cells

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26 Jan 2015
project

Classical/Additive Transgenesis by Microinjection

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27 Jun 2014
publication

Human hematopoietic reconstitution and HLA-restricted responses in nonpermissive alymphoid mice

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24 Jun 2014
publication

A novel nodal enhancer dependent on pluripotency factors and smad2/3 signaling conditions a regulatory switch during epiblast maturation

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06 Jun 2014
publication

Cellular and behavioral outcomes of dorsal striatonigral neuron ablation: new insights into striatal functions

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04 May 2014
publication

Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for the development of an universal CD8+ T-cell epitope-based vaccine

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03 Feb 2014
publication

Protective role of LGP2 in influenza virus pathogenesis

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17 Jun 2013
publication

HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 monochain transgenic/H-2 class I null mice: novel versatile preclinical models of human T cell responses

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12 Jun 2013
publication

Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis

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20 Dec 2012
publication

Generation and characterization of a tamoxifen inducible Msx1(CreERT2) knock-in allele

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29 Jul 2012
publication

Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury

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11 Jul 2012
publication

The four and a half LIM-only protein 2 regulates liver homeostasis and contributes to carcinogenesis

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26 Jun 2012
publication

I-SceI-mediated double-strand break does not increase the frequency of homologous recombination at the Dct locus in mouse embryonic stem cells

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01 Apr 2012
publication

Loss of central and peripheral CD8+ T-cell tolerance to HFE in mouse models of human familial hemochromatosis

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18 Oct 2011
publication

Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination

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23 Sep 2010
publication

Lineage relationship analysis of RORgammat+ innate lymphoid cells

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24 Dec 2009
publication

Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase

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21 Jan 2009
publication

Characterization of the thymic IL-7 niche in vivo

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17 Sep 2008
publication

Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis

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26 May 2008
publication

In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells

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01 May 2008
publication

Generation of an Msx2-GFP conditional null allele

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23 Mar 2007
publication

Conditional knock-out reveals that zygotic vezatin-null mouse embryos die at implantation

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01 Mar 2007
publication

The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo

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25 Jun 2006
publication

Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy

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