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  • nrc
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  • Associate Professor
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  • Full Professor
  • Graduate Student
  • Lab assistant
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  • PhD Student
  • Physician
  • Post-doc
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  • Retired scientist
  • Technician
  • Undergraduate Student
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Structure
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  • Labex Coordinator
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Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
06
Feb 2015
Status
Ongoing
Members
4
Structures
1

About

We have an increasing experience in modification on rat genome using lentiviral vectors and Zinc Finger Nucleases (ZFNs). Rat models are more convenient for surgery, due to their medium size, and constitute a robust physiological model for pharmacological studies. Rats give also better models for neurology (specially behaviour studies), hypertension, diabetes and also some cancers (sarcoma, breast cancer) where they mimic more accurately the human disease.