Timeline

Nancy Guillen
Visiting Scientist
09 Mar 2021
publication

Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator.

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12 Jan 2021
project

Insights into amebiasis using a human 3D-intestinal model (ANR-14-IFEC-0001-02)

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08 Jan 2021
project

Understanding the Pathogenicity of Entamoeba Using Comparative Transcriptomics and Phylogenomics – GENAMIBE. Project-ANR-10-GENM-0011

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08 Jan 2021
publication

Bioimage Analysis and Cell Motility

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22 Dec 2020
project

Impact of tissue components on cell migration: adhesion strength, cell morpho-dynamics and intracellular biophysics parameters.

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23 Nov 2020
publication

Signals and signal transduction pathways in Entamoeba histolytica during the life cycle and when interacting with bacteria or human cells

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19 Nov 2020
publication

Genomic determinants for initiation and length of natural antisense transcripts in Entamoeba histolytica

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21 Oct 2020
publication

Human intestinal models to study interactions between intestine and microbes

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01 Aug 2020
publication

Insights into amebiasis using a human 3D-intestinal model.

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04 Jun 2020
publication

A Protocol to Quantify Cellular Morphodynamics: From Cell Labelling to Automatic Image Analysis

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02 Jun 2020
publication

Human Immune Response Triggered by Entamoeba histolytica in a 3D-Intestinal Model

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04 Oct 2019
event

Eukaryome Impact on Intestine homeostasis and mucosal immunology

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01 Oct 2019
publication

Treatment of Breast Cancer With Gonadotropin-Releasing Hormone Analogs

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03 May 2019
publication

The interaction between Entamoeba histolytica and enterobacteria shed light on an ancient antibacterial response

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10 Apr 2019
publication

Acetylation is the most abundant actin modification in Entamoeba histolytica and modifications of actin’s amino-terminal domain change cytoskeleton activities

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01 Mar 2019
publication

Genetic Diversity and Gene Family Expansions in Members of the Genus Entamoeba

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08 Jan 2019
publication

Entamoeba histolytica Up-Regulates MicroRNA-643 to Promote Apoptosis by Targeting XIAP in Human Epithelial Colon Cells

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29 Oct 2018
publication

Reassessing the Role of Entamoeba gingivalis in Periodontitis

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03 Jul 2018
publication

Morphodynamics of the Actin-Rich Cytoskeleton in Entamoeba histolytica

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13 Jun 2018
publication

Enteric bacteria boost defences against oxidative stress in Entamoeba histolytica

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09 Apr 2018
publication

Targeting the polyadenylation factor EhCFIm25 with RNA aptamers controls survival in Entamoeba histolytica

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15 Jan 2018
publication

Activation of human gonadotropin-releasing hormone receptor promotes down regulation of ARHGAP18 and regulates the cell invasion of MDA-MB-231 cells

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07 Dec 2017
publication

Crosstalk between Entamoeba histolytica and the human intestinal tract during amoebiasis

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12 Oct 2017
publication

Silencing the cleavage factor CFIm25 as a new strategy to control Entamoeba histolytica parasite

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23 Aug 2017
publication

BioFlow: a non-invasive, image-based method to measure speed, pressure and forces inside living cells

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08 Dec 2016
publication

The motility of Entamoeba histolytica: finding ways to understand intestinal amoebiasis

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21 Oct 2016
publication

Extensive transcriptome analysis correlates the plasticity of Entamoeba histolytica pathogenesis to rapid phenotype changes depending on the environment

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23 Apr 2016
publication

A New Nucleocytoplasmic RhoGAP Protein Contributes to Control the Pathogenicity of Entamoeba histolytica by Regulating EhRacC and EhRacD Activity

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16 Apr 2016
publication

Biophysical measurements in 2D and 3D live cell imaging using fluid dynamics and optical flow

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26 Feb 2016
publication

Intracellular traffic of the lysine and glutamic acid rich protein KERP1 reveals features of endomembrane organization in Entamoeba histolytica

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10 Feb 2016
publication

Human Liver Infection in a Dish: Easy-To-Build 3D Liver Models for Studying Microbial Infection

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21 Jan 2016
publication

Multinucleation and Polykaryon Formation is Promoted by the EhPC4 Transcription Factor in Entamoeba histolytica

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13 Oct 2015
publication

Amoeboid movement in protozoan pathogens

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11 Sep 2015
software

GRAAL: genome assembly from chromosome contact frequencies

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06 Jul 2015
publication

In Entamoeba histolytica, a BspA family protein is required for chemotaxis toward tumour necrosis factor

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06 Jun 2015
project

Imaging and mathematical modelling of cell morphology and motility

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18 Feb 2015
publication

Maintenance of intracellular hypoxia and adequate heat shock response are essential requirements for pathogenicity and virulence of Entamoeba histolytica

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02 Dec 2014
team

Biological Image Analysis

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07 Oct 2014
publication

The parasite Entamoeba histolytica exploits the activities of human matrix metalloproteinases to invade colonic tissue

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11 Sep 2014
publication

A new human 3D-liver model unravels the role of galectins in liver infection by the parasite Entamoeba histolytica

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11 Sep 2014
publication

Gene expression profiling in Entamoeba histolytica identifies key components in iron uptake and metabolism

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03 Sep 2014
publication

Data set for the proteomics analysis of the endomembrane system from the unicellular Entamoeba histolytica

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07 Aug 2014
publication

Cellular and proteomics analysis of the endomembrane system from the unicellular Entamoeba histolytica

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02 Jul 2014
publication

Proteomic analysis identifies endoribouclease EhL-PSP and EhRRP41 exosome protein as novel interactors of EhCAF1 deadenylase

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09 Apr 2014
publication

Infection biology: Nibbled to death

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08 Apr 2014
publication

Proteomic profiling reveals that EhPC4 transcription factor induces cell migration through up-regulation of the 16-kDa actin-binding protein EhABP16 in Entamoeba histolytica

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09 Jan 2014
publication

Bioassay-guided fractionation of extracts from Codiaeum variegatum against Entamoeba histolytica discovers compounds that modify expression of ceramide biosynthesis related genes

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19 Dec 2013
publication

Identification of the virulence landscape essential for Entamoeba histolytica invasion of the human colon

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01 Feb 2013
publication

Quantification of stochastic noise of splicing and polyadenylation in Entamoeba histolytica

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30 Jan 2013
publication

The α-helical regions of KERP1 are important in Entamoeba histolytica adherence to human cells

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22 Oct 2012
publication

Identification of dihydropyrimidine dehydrogenase as a virulence factor essential for the survival of Entamoeba histolytica in glucose-poor environments

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24 Sep 2012
publication

mRNA decay proteins are targeted to poly(A)+ RNA and dsRNA-containing cytoplasmic foci that resemble P-bodies in Entamoeba histolytica

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20 Aug 2012
publication

A functional study of nucleocytoplasmic transport signals of the EhNCABP166 protein from Entamoeba histolytica

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16 Jun 2012
publication

Virulence and virulence factors in Entamoeba histolytica, the agent of human amoebiasis

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24 Feb 2012
publication

Endoplasmic reticulum stress-sensing mechanism is activated in Entamoeba histolytica upon treatment with nitric oxide

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15 Feb 2012
publication

Newly visualized fibrillar collagen scaffolds dictate Entamoeba histolytica invasion route in the human colon

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12 Jan 2012
publication

Porcine colon explants in the study of innate immune response to Entamoeba histolytica

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21 Dec 2011
publication

Towards the establishment of a porcine model to study human amebiasis

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02 Aug 2011
publication

Glucose starvation boosts Entamoeba histolytica virulence

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30 May 2011
publication

Human liver sinusoidal endothelial cells respond to interaction with Entamoeba histolytica by changes in morphology, integrin signalling and cell death

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05 Apr 2011
publication

A proteomic and cellular analysis of uropods in the pathogen Entamoeba histolytica

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01 Mar 2011
publication

New insights into host-pathogen interactions during Entamoeba histolytica liver infection

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30 Dec 2010
publication

3-D active meshes: fast discrete deformable models for cell tracking in 3-D time-lapse microscopy

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27 Oct 2010
publication

Dynamic instability of the intracellular pressure drives bleb-based motility

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06 Jan 2010
publication

Epithelial induction of porcine suppressor of cytokine signaling 2 (SOCS2) gene expression in response to Entamoeba histolytica

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23 Dec 2009
publication

Use of bacterially expressed dsRNA to downregulate Entamoeba histolytica gene expression

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17 Nov 2009
publication

An ex-vivo human intestinal model to study Entamoeba histolytica pathogenesis

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08 Jul 2009
publication

DNA repair mechanisms in eukaryotes: Special focus in Entamoeba histolytica and related protozoan parasites

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01 Jan 2009
publication

Host-microbe interactions and defense mechanisms in the development of amoebic liver abscesses

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24 Dec 2008
publication

Effects of DNA damage induced by UV irradiation on gene expression in the protozoan parasite Entamoeba histolytica

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24 Dec 2008
publication

Broad early immune response of porcine epithelial jejunal IPI-2I cells to Entamoeba histolytica

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09 Aug 2008
publication

Putative DEAD and DExH-box RNA helicases families in Entamoeba histolytica

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16 Apr 2008
publication

Chemotaxis of Entamoeba histolytica towards the pro-inflammatory cytokine TNF is based on PI3K signalling, cytoskeleton reorganization and the Galactose/N-acetylgalactosamine lectin activity

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12 Apr 2008
publication

In silico analysis of EST and genomic sequences allowed the prediction of cis-regulatory elements for Entamoeba histolytica mRNA polyadenylation

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11 Mar 2008
publication

Calcium-binding protein 1 of Entamoeba histolytica transiently associates with phagocytic cups in a calcium-independent manner

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13 Feb 2008
publication

Bioinformatics and functional analysis of an Entamoeba histolytica mannosyltransferase necessary for parasite complement resistance and hepatical infection

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01 Jan 2008
publication

Silencing genes by RNA interference in the protozoan parasite Entamoeba histolytica

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04 Dec 2007
publication

Trichostatin A regulates peroxiredoxin expression and virulence of the parasite Entamoeba histolytica

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19 Nov 2007
publication

The endoplasmic reticulum chaperone calreticulin is recruited to the uropod during capping of surface receptors in Entamoeba histolytica

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01 Nov 2007
publication

Novel structural and functional findings of the ehFLN protein from Entamoeba histolytica

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17 Aug 2007
publication

The lysine- and glutamic acid-rich protein KERP1 plays a role in Entamoeba histolytica liver abscess pathogenesis

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01 Jan 2007
publication

Structure and content of the Entamoeba histolytica genome

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21 Nov 2006
publication

Initiation of inflammation and cell death during liver abscess formation by Entamoeba histolytica depends on activity of the galactose/N-acetyl-D-galactosamine lectin

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01 May 2006
publication

Stress by heat shock induces massive down regulation of genes and allows differential allelic expression of the Gal/GalNAc lectin in Entamoeba histolytica

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01 Feb 2006
publication

Human tumor necrosis factor is a chemoattractant for the parasite Entamoeba histolytica

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01 Feb 2006
publication

Host tissue invasion by Entamoeba histolytica is powered by motility and phagocytosis

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10 Jan 2006
publication

Signaling through the phosphatidylinositol 3-kinase regulates mechanotaxis induced by local low magnetic forces in Entamoeba histolytica

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28 Nov 2005
publication

Genomic and proteomic approaches highlight phagocytosis of living and apoptotic human cells by the parasite Entamoeba histolytica

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02 Nov 2005
publication

The ABP-120 C-end region from Entamoeba histolytica interacts with sulfatide, a new lipid target

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01 Oct 2005
publication

Signalization and cytoskeleton activity through myosin IB during the early steps of phagocytosis in Entamoeba histolytica: a proteomic approach

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01 Apr 2005
publication

A lysine- and glutamic acid-rich protein, KERP1, from Entamoeba histolytica binds to human enterocytes

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01 Mar 2005
publication

Roles of cell adhesion and cytoskeleton activity in Entamoeba histolytica pathogenesis: a delicate balance

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24 Feb 2005
publication

The genome of the protist parasite Entamoeba histolytica

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12 Feb 2005
publication

Acto-myosin cytoskeleton dependent viscosity and shear-thinning behavior of the amoeba cytoplasm

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26 Jan 2005
publication

Entamoeba histolytica: inhibition of cellular functions by overexpression of EhGEF1, a novel Rho/Rac guanine nucleotide exchange factor

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01 Jan 2005
publication

Myosin II and the Gal-GalNAc lectin play a crucial role in tissue invasion by Entamoeba histolytica

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01 Nov 2004
publication

Double-stranded RNA mediates homology-dependent gene silencing of gamma-tubulin in the human parasite Entamoeba histolytica

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15 Jul 2004
publication

Calcium binding protein 1 of the protozoan parasite Entamoeba histolytica interacts with actin and is involved in cytoskeleton dynamics

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01 Jul 2004
publication

Overexpression of myosin IB in living Entamoeba histolytica enhances cytoplasm viscosity and reduces phagocytosis

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01 May 2004
publication

Signal transduction through the Gal-GalNAc lectin of Entamoeba histolytica involves a spectrin-like protein

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01 Apr 2003
publication

L10 ribosomal protein from Entamoeba histolytica share structural and functional homologies with QM/Jif-1: proteins with extraribosomal functions

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01 Jan 2003
publication

EhPAK, a member of the p21-activated kinase family, is involved in the control of Entamoeba histolytica migration and phagocytosis

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01 Oct 2002
publication

Segmentation and tracking of migrating cells in videomicroscopy with parametric active contours: a tool for cell-based drug testing

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01 Jun 2002
publication

Fate of Entamoeba histolytica during establishment of amoebic liver abscess analyzed by quantitative radioimaging and histology

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01 Dec 2000
publication

Molecular cloning and cellular localization of an unusual bipartite Entamoeba histolytica polypeptide with similarity to actin binding proteins

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01 Jul 2000
publication

DNA cloning of the Entamoeba histolytica PRP6 gene: a putative U4/U6 small nuclear ribonucleoprotein particle (snRNP)

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01 Jul 2000
publication

Cellular and biochemical analysis of phagocytosis in Entamoeba histolytica

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01 Jul 2000
publication

The interplay between receptor capping and cytoskeleton remodeling in Entamoeba histolytica

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01 Jul 2000
publication

Cytoskeleton activities during the interaction of Entamoeba histolytica with epithelial cells

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01 Jul 2000
publication

Distribution of a potential p21-activated serine/threonine kinase (PAK) in Entamoeba histolytica

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01 May 2000
publication

Cell polarization and adhesion in a motile pathogenic protozoan: role and fate of the Entamoeba histolytica Gal/GalNAc lectin

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01 Nov 1999
publication

New insights into the role of the cytoskeleton in phagocytosis of Entamoeba histolytica

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01 Apr 1999
publication

Myosin IB from Entamoeba histolytica is involved in phagocytosis of human erythrocytes

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01 Jul 1998
publication

The pyruvate:ferredoxin oxidoreductase enzyme is located in the plasma membrane and in a cytoplasmic structure in Entamoeba

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01 Jun 1998
publication

Virulence and functions of myosin II are inhibited by overexpression of light meromyosin in Entamoeba histolytica

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01 Jun 1998
publication

Cytoskeletal actin and its associated proteins. Some examples in Protista

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01 Jun 1998
publication

The small GTP-binding protein RacG regulates uroid formation in the protozoan parasite Entamoeba histolytica

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01 Nov 1997
publication

Protection against invasive amebiasis by a single monoclonal antibody directed against a lipophosphoglycan antigen localized on the surface of Entamoeba histolytica

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01 Oct 1997
publication

Interaction between Entamoeba histolytica and intestinal epithelial cells involves a CD44 cross-reactive protein expressed on the parasite surface

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01 May 1997
publication

Molecular characterization of myosin IB from the lower eukaryote Entamoeba histolytica, a human parasite

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01 Jan 1997
publication

The tail domain of Entamoeba histolytica myosin IB bind F-actin

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01 Jan 1997
publication

Rac G, a small GTPase, regulates capping of surface receptors in Entamoeba histolytica

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01 Dec 1996
publication

Identification and cellular localization of the actin-binding protein ABP-120 from Entamoeba histolytica

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01 May 1996
publication

Role of signalling and cytoskeletal rearrangements in the pathogenesis of Entamoeba histolytica

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01 Nov 1995
publication

Myosin II is involved in capping and uroid formation in the human pathogen Entamoeba histolytica

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01 Oct 1993
publication

Cell signalling and motility in Entamoeba histolytica

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01 May 1993
publication

Identification and characterization of a myosin heavy chain gene (mhcA) from the human parasitic pathogen Entamoeba histolytica

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01 Mar 1993
publication

Localization of myosin heavy chain A in the human pathogen Entamoeba histolytica

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01 Jan 1992
publication

Identification of a myosin heavy chain gene from Entamoeba histolytica

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