Timeline
Nancy Guillen
Visiting Scientist
21 Oct 2023
publication
Encystation and Stress Responses under the Control of Ubiquitin-like Proteins in Pathogenic Amoebae
Read more13 May 2023
publication
Live Cells Imaging and Comparative Phosphoproteomics Uncover Proteins from the Mechanobiome in Entamoeba histolytica.
Read more04 Jan 2023
08 Feb 2022
publication
RNA Sequencing Reveals Widespread Transcription of Natural Antisense RNAs in Entamoeba Species
Read more09 Mar 2021
publication
Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator.
Read more12 Jan 2021
08 Jan 2021
project
Understanding the Pathogenicity of Entamoeba Using Comparative Transcriptomics and Phylogenomics – GENAMIBE. Project-ANR-10-GENM-0011
Read more08 Jan 2021
22 Dec 2020
project
Impact of tissue components on cell migration: adhesion strength, cell morpho-dynamics and intracellular biophysics parameters.
Read more23 Nov 2020
publication
Signals and signal transduction pathways in Entamoeba histolytica during the life cycle and when interacting with bacteria or human cells
Read more19 Nov 2020
publication
Genomic determinants for initiation and length of natural antisense transcripts in Entamoeba histolytica.
Read more21 Oct 2020
01 Aug 2020
04 Jun 2020
publication
A Protocol to Quantify Cellular Morphodynamics: From Cell Labelling to Automatic Image Analysis
Read more02 Jun 2020
publication
Human Immune Response Triggered by Entamoeba histolytica in a 3D-Intestinal Model
Read more04 Oct 2019
01 Oct 2019
03 May 2019
publication
The interaction between Entamoeba histolytica and enterobacteria shed light on an ancient antibacterial response
Read more10 Apr 2019
publication
Acetylation is the most abundant actin modification in Entamoeba histolytica and modifications of actin’s amino-terminal domain change cytoskeleton activities
Read more01 Mar 2019
publication
Genetic Diversity and Gene Family Expansions in Members of the Genus Entamoeba
Read more08 Jan 2019
publication
Entamoeba histolytica Up-Regulates MicroRNA-643 to Promote Apoptosis by Targeting XIAP in Human Epithelial Colon Cells
Read more29 Oct 2018
03 Jul 2018
13 Jun 2018
publication
Enteric bacteria boost defences against oxidative stress in Entamoeba histolytica
Read more09 Apr 2018
publication
Targeting the polyadenylation factor EhCFIm25 with RNA aptamers controls survival in Entamoeba histolytica
Read more15 Jan 2018
publication
Activation of human gonadotropin-releasing hormone receptor promotes down regulation of ARHGAP18 and regulates the cell invasion of MDA-MB-231 cells
Read more07 Dec 2017
publication
Crosstalk between Entamoeba histolytica and the human intestinal tract during amoebiasis
Read more12 Oct 2017
publication
Silencing the cleavage factor CFIm25 as a new strategy to control Entamoeba histolytica parasite
Read more23 Aug 2017
publication
BioFlow: a non-invasive, image-based method to measure speed, pressure and forces inside living cells.
Read more01 Dec 2016
publication
The motility of Entamoeba histolytica: finding ways to understand intestinal amoebiasis.
Read more21 Oct 2016
publication
Extensive transcriptome analysis correlates the plasticity of Entamoeba histolytica pathogenesis to rapid phenotype changes depending on the environment
Read more23 Apr 2016
publication
A New Nucleocytoplasmic RhoGAP Protein Contributes to Control the Pathogenicity of Entamoeba histolytica by Regulating EhRacC and EhRacD Activity
Read more16 Apr 2016
publication
Biophysical measurements in 2D and 3D live cell imaging using fluid dynamics and optical flow
Read more26 Feb 2016
publication
Intracellular traffic of the lysine and glutamic acid rich protein KERP1 reveals features of endomembrane organization in Entamoeba histolytica
Read more10 Feb 2016
publication
Human Liver Infection in a Dish: Easy-To-Build 3D Liver Models for Studying Microbial Infection
Read more21 Jan 2016
publication
Multinucleation and Polykaryon Formation is Promoted by the EhPC4 Transcription Factor in Entamoeba histolytica
Read more13 Oct 2015
11 Sep 2015
06 Jul 2015
publication
In Entamoeba histolytica, a BspA family protein is required for chemotaxis toward tumour necrosis factor
Read more06 Jun 2015
18 Feb 2015
publication
Maintenance of intracellular hypoxia and adequate heat shock response are essential requirements for pathogenicity and virulence of Entamoeba histolytica
Read more02 Dec 2014
07 Oct 2014
publication
The parasite Entamoeba histolytica exploits the activities of human matrix metalloproteinases to invade colonic tissue
Read more11 Sep 2014
publication
A new human 3D-liver model unravels the role of galectins in liver infection by the parasite Entamoeba histolytica
Read more11 Sep 2014
publication
Gene expression profiling in Entamoeba histolytica identifies key components in iron uptake and metabolism
Read more03 Sep 2014
publication
Data set for the proteomics analysis of the endomembrane system from the unicellular Entamoeba histolytica
Read more07 Aug 2014
publication
Cellular and proteomics analysis of the endomembrane system from the unicellular Entamoeba histolytica
Read more02 Jul 2014
publication
Proteomic analysis identifies endoribouclease EhL-PSP and EhRRP41 exosome protein as novel interactors of EhCAF1 deadenylase
Read more09 Apr 2014
08 Apr 2014
publication
Proteomic profiling reveals that EhPC4 transcription factor induces cell migration through up-regulation of the 16-kDa actin-binding protein EhABP16 in Entamoeba histolytica
Read more09 Jan 2014
publication
Bioassay-guided fractionation of extracts from Codiaeum variegatum against Entamoeba histolytica discovers compounds that modify expression of ceramide biosynthesis related genes
Read more19 Dec 2013
publication
Identification of the virulence landscape essential for Entamoeba histolytica invasion of the human colon
Read more01 Feb 2013
publication
Quantification of stochastic noise of splicing and polyadenylation in Entamoeba histolytica
Read more30 Jan 2013
publication
The α-helical regions of KERP1 are important in Entamoeba histolytica adherence to human cells
Read more22 Oct 2012
publication
Identification of dihydropyrimidine dehydrogenase as a virulence factor essential for the survival of Entamoeba histolytica in glucose-poor environments
Read more24 Sep 2012
publication
mRNA decay proteins are targeted to poly(A)+ RNA and dsRNA-containing cytoplasmic foci that resemble P-bodies in Entamoeba histolytica
Read more20 Aug 2012
publication
A functional study of nucleocytoplasmic transport signals of the EhNCABP166 protein from Entamoeba histolytica
Read more16 Jun 2012
publication
Virulence and virulence factors in Entamoeba histolytica, the agent of human amoebiasis
Read more24 Feb 2012
publication
Endoplasmic reticulum stress-sensing mechanism is activated in Entamoeba histolytica upon treatment with nitric oxide
Read more15 Feb 2012
publication
Newly visualized fibrillar collagen scaffolds dictate Entamoeba histolytica invasion route in the human colon
Read more12 Jan 2012
publication
Porcine colon explants in the study of innate immune response to Entamoeba histolytica
Read more21 Dec 2011
02 Aug 2011
30 May 2011
publication
Human liver sinusoidal endothelial cells respond to interaction with Entamoeba histolytica by changes in morphology, integrin signalling and cell death
Read more05 Apr 2011
publication
A proteomic and cellular analysis of uropods in the pathogen Entamoeba histolytica
Read more01 Mar 2011
publication
New insights into host-pathogen interactions during Entamoeba histolytica liver infection
Read more30 Dec 2010
publication
3-D active meshes: fast discrete deformable models for cell tracking in 3-D time-lapse microscopy
Read more27 Oct 2010
06 Jan 2010
publication
Epithelial induction of porcine suppressor of cytokine signaling 2 (SOCS2) gene expression in response to Entamoeba histolytica
Read more23 Dec 2009
publication
Use of bacterially expressed dsRNA to downregulate Entamoeba histolytica gene expression
Read more17 Nov 2009
08 Jul 2009
publication
DNA repair mechanisms in eukaryotes: Special focus in Entamoeba histolytica and related protozoan parasites
Read more01 Jan 2009
publication
Host-microbe interactions and defense mechanisms in the development of amoebic liver abscesses
Read more24 Dec 2008
publication
Effects of DNA damage induced by UV irradiation on gene expression in the protozoan parasite Entamoeba histolytica
Read more24 Dec 2008
publication
Broad early immune response of porcine epithelial jejunal IPI-2I cells to Entamoeba histolytica
Read more09 Aug 2008
16 Apr 2008
publication
Chemotaxis of Entamoeba histolytica towards the pro-inflammatory cytokine TNF is based on PI3K signalling, cytoskeleton reorganization and the Galactose/N-acetylgalactosamine lectin activity
Read more12 Apr 2008
publication
In silico analysis of EST and genomic sequences allowed the prediction of cis-regulatory elements for Entamoeba histolytica mRNA polyadenylation
Read more11 Mar 2008
publication
Calcium-binding protein 1 of Entamoeba histolytica transiently associates with phagocytic cups in a calcium-independent manner
Read more13 Feb 2008
publication
Bioinformatics and functional analysis of an Entamoeba histolytica mannosyltransferase necessary for parasite complement resistance and hepatical infection
Read more01 Jan 2008
publication
Silencing genes by RNA interference in the protozoan parasite Entamoeba histolytica
Read more04 Dec 2007
publication
Trichostatin A regulates peroxiredoxin expression and virulence of the parasite Entamoeba histolytica
Read more19 Nov 2007
publication
The endoplasmic reticulum chaperone calreticulin is recruited to the uropod during capping of surface receptors in Entamoeba histolytica
Read more01 Nov 2007
publication
Novel structural and functional findings of the ehFLN protein from Entamoeba histolytica
Read more17 Aug 2007
publication
The lysine- and glutamic acid-rich protein KERP1 plays a role in Entamoeba histolytica liver abscess pathogenesis
Read more01 Jan 2007
21 Nov 2006
publication
Initiation of inflammation and cell death during liver abscess formation by Entamoeba histolytica depends on activity of the galactose/N-acetyl-D-galactosamine lectin
Read more01 May 2006
publication
Stress by heat shock induces massive down regulation of genes and allows differential allelic expression of the Gal/GalNAc lectin in Entamoeba histolytica
Read more01 Feb 2006
publication
Host tissue invasion by Entamoeba histolytica is powered by motility and phagocytosis
Read more01 Feb 2006
publication
Human tumor necrosis factor is a chemoattractant for the parasite Entamoeba histolytica
Read more10 Jan 2006
publication
Signaling through the phosphatidylinositol 3-kinase regulates mechanotaxis induced by local low magnetic forces in Entamoeba histolytica
Read more28 Nov 2005
publication
Genomic and proteomic approaches highlight phagocytosis of living and apoptotic human cells by the parasite Entamoeba histolytica
Read more02 Nov 2005
publication
The ABP-120 C-end region from Entamoeba histolytica interacts with sulfatide, a new lipid target
Read more01 Oct 2005
publication
Signalization and cytoskeleton activity through myosin IB during the early steps of phagocytosis in Entamoeba histolytica: a proteomic approach
Read more01 Apr 2005
publication
A lysine- and glutamic acid-rich protein, KERP1, from Entamoeba histolytica binds to human enterocytes
Read more01 Mar 2005
publication
Roles of cell adhesion and cytoskeleton activity in Entamoeba histolytica pathogenesis: a delicate balance
Read more24 Feb 2005
12 Feb 2005
publication
Acto-myosin cytoskeleton dependent viscosity and shear-thinning behavior of the amoeba cytoplasm
Read more26 Jan 2005
publication
Entamoeba histolytica: inhibition of cellular functions by overexpression of EhGEF1, a novel Rho/Rac guanine nucleotide exchange factor
Read more01 Jan 2005
publication
Myosin II and the Gal-GalNAc lectin play a crucial role in tissue invasion by Entamoeba histolytica
Read more01 Nov 2004
publication
Double-stranded RNA mediates homology-dependent gene silencing of gamma-tubulin in the human parasite Entamoeba histolytica
Read more15 Jul 2004
publication
Calcium binding protein 1 of the protozoan parasite Entamoeba histolytica interacts with actin and is involved in cytoskeleton dynamics
Read more01 Jul 2004
publication
Overexpression of myosin IB in living Entamoeba histolytica enhances cytoplasm viscosity and reduces phagocytosis
Read more01 May 2004
publication
Signal transduction through the Gal-GalNAc lectin of Entamoeba histolytica involves a spectrin-like protein
Read more01 Apr 2003
publication
L10 ribosomal protein from Entamoeba histolytica share structural and functional homologies with QM/Jif-1: proteins with extraribosomal functions
Read more01 Jan 2003
publication
EhPAK, a member of the p21-activated kinase family, is involved in the control of Entamoeba histolytica migration and phagocytosis
Read more01 Oct 2002
publication
Segmentation and tracking of migrating cells in videomicroscopy with parametric active contours: a tool for cell-based drug testing
Read more01 Jun 2002
publication
Fate of Entamoeba histolytica during establishment of amoebic liver abscess analyzed by quantitative radioimaging and histology
Read more01 Dec 2000
publication
Molecular cloning and cellular localization of an unusual bipartite Entamoeba histolytica polypeptide with similarity to actin binding proteins
Read more01 Jul 2000
publication
DNA cloning of the Entamoeba histolytica PRP6 gene: a putative U4/U6 small nuclear ribonucleoprotein particle (snRNP)
Read more01 Jul 2000
01 Jul 2000
publication
The interplay between receptor capping and cytoskeleton remodeling in Entamoeba histolytica
Read more01 Jul 2000
publication
Cytoskeleton activities during the interaction of Entamoeba histolytica with epithelial cells
Read more01 Jul 2000
publication
Distribution of a potential p21-activated serine/threonine kinase (PAK) in Entamoeba histolytica
Read more01 May 2000
publication
Cell polarization and adhesion in a motile pathogenic protozoan: role and fate of the Entamoeba histolytica Gal/GalNAc lectin
Read more01 Nov 1999
publication
New insights into the role of the cytoskeleton in phagocytosis of Entamoeba histolytica
Read more01 Apr 1999
publication
Myosin IB from Entamoeba histolytica is involved in phagocytosis of human erythrocytes
Read more01 Jul 1998
publication
The pyruvate:ferredoxin oxidoreductase enzyme is located in the plasma membrane and in a cytoplasmic structure in Entamoeba
Read more01 Jun 1998
publication
Virulence and functions of myosin II are inhibited by overexpression of light meromyosin in Entamoeba histolytica
Read more01 Jun 1998
01 Jun 1998
publication
The small GTP-binding protein RacG regulates uroid formation in the protozoan parasite Entamoeba histolytica
Read more01 Nov 1997
publication
Protection against invasive amebiasis by a single monoclonal antibody directed against a lipophosphoglycan antigen localized on the surface of Entamoeba histolytica
Read more01 Oct 1997
publication
Interaction between Entamoeba histolytica and intestinal epithelial cells involves a CD44 cross-reactive protein expressed on the parasite surface
Read more01 May 1997
publication
Molecular characterization of myosin IB from the lower eukaryote Entamoeba histolytica, a human parasite
Read more01 Jan 1997
01 Jan 1997
publication
Rac G, a small GTPase, regulates capping of surface receptors in Entamoeba histolytica
Read more01 Dec 1996
publication
Identification and cellular localization of the actin-binding protein ABP-120 from Entamoeba histolytica
Read more01 May 1996
publication
Role of signalling and cytoskeletal rearrangements in the pathogenesis of Entamoeba histolytica
Read more01 Nov 1995
publication
Myosin II is involved in capping and uroid formation in the human pathogen Entamoeba histolytica
Read more01 Oct 1993
01 May 1993
publication
Identification and characterization of a myosin heavy chain gene (mhcA) from the human parasitic pathogen Entamoeba histolytica
Read more01 Mar 1993
publication
Localization of myosin heavy chain A in the human pathogen Entamoeba histolytica
Read more01 Jan 1992