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© Research
Publication : Infection and immunity

Human tumor necrosis factor is a chemoattractant for the parasite Entamoeba histolytica

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Infection and immunity - 01 Feb 2006

Blazquez S, Zimmer C, Guigon G, Olivo-Marin JC, Guillén N, Labruyère E

Link to Pubmed [PMID] – 16428794

Infect. Immun. 2006 Feb;74(2):1407-11

In an analysis of the molecular factors triggering amebiasis, we investigated the chemotaxis of Entamoeba histolytica toward tumor necrosis factor (TNF) in vitro, using quantitative imaging techniques. Our findings enabled us to propose a hitherto unknown role for TNF as a chemokinetic and chemoattractant agent for this parasite.

http://www.ncbi.nlm.nih.gov/pubmed/16428794