Timeline

Hugo Mouquet
Head of Structure
04 Jul 2019
publication

TLR9 Signaling in HCV-Associated Atypical Memory B Cells Triggers Th1 and Rheumatoid Factor Autoantibody Responses

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10 May 2019
event

Groupe de Réflexion SIDA (GRS) meeting: “Mechanisms of HIV antigen presentation”

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09 Apr 2019
publication

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells

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08 Apr 2019
event

Groupe de Reflexion SIDA (GRS) seminar: “Determinants of HIV-1 broadly neutralizing antibody induction”

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04 Mar 2019
event

Groupe de Réflexion SIDA (GRS) meeting: “Mechanisms of restriction of viral entry”

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31 Jan 2019
project

Archive of the Group for AIDS Research

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21 Nov 2018
event

Groupe de Reflexion SIDA (GRS) seminar: “Tissue-like 3D environment shape modes of HIV-spread”

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18 Sep 2018
event

Groupe de Réflexion SIDA (GRS) seminar: “Defining Correlates of Immunology using Systems Serology”

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31 Jul 2018
publication

A human immune system mouse model with robust lymph node development

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29 May 2018
publication

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity

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22 May 2018
event

Groupe de Réflexion SIDA (GRS) meeting: “Humanized mice models for HIV studies”

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09 Apr 2018
publication

Early Antiretroviral Therapy Preserves Functional Follicular Helper T and HIV-Specific B Cells in the Gut Mucosa of HIV-1-Infected Individuals

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27 Feb 2018
event

GRS (Groupe de Réflexion SIDA) meeting: “Immune reconstitution in HIV infection”

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02 Feb 2018
event

Groupe de Réflexion SIDA (GRS) meeting: “Metabolism and HIV”

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30 Nov 2017
publication

Humanized mouse models to study pathophysiology and treatment of HIV infection

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29 Nov 2017
publication

Genetically intact but functionally impaired HIV-1 Env glycoproteins in the T-cell reservoir

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31 Oct 2017
event

Groupe de Réflexion SIDA (GRS) meeting: “HIV vaccination strategies”

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19 Jun 2017
publication

What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Lessons from the Antibody Response to HIV-1

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19 Jun 2017
publication

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

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31 May 2017
publication

HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection

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18 Apr 2017
publication

Hunting Down the HIV-1 Reservoir: A Starring Role for Antibodies?

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06 Apr 2017
event

GRS (Groupe de Reflexion SIDA) meeting: “Residual risk of HIV sexual transmission”

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15 Mar 2017
event

Patrick Wilson seminar

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21 Feb 2017
publication

Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity

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15 Feb 2017
event

Bernardo Reina San Martin seminar

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25 Jan 2017
publication

Lack of ADCC Breadth of Human Nonneutralizing Anti-HIV-1 Antibodies

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16 Jan 2017
publication

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

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14 Dec 2016
publication

Broadly neutralizing antibodies suppress post-transcytosis HIV-1 infectivity

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12 Sep 2016
publication

[Antibodies that kill HIV-1-infected cells]

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29 Jul 2016
publication

Scarcity of autoreactive human blood IgA(+) memory B cells

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03 Mar 2016
news

Antibodies capable of eliminating HIV-infected cells

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03 Mar 2016
publication

Elimination of HIV-1-infected cells by broadly neutralizing antibodies

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01 Mar 2016
publication

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1

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12 Feb 2016
project

Group for AIDS Research

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07 Sep 2015
project

Influence of ART Timing on Mucosal B-cell Responses in HIV-1 Infected Individuals

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07 Sep 2015
project

Clonal B cells in Cryoglobulinemia Vasculitis with Hepatitits C Infection

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29 Jul 2015
project

Antiviral Properties of Broadly Neutralizing HIV-1 Antibodies

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29 Jul 2015
project

ERC-2013-StG HumAntiViruses

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11 Jul 2015
publication

Tailored immunogens for rationally designed antibody-based HIV-1 vaccines

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01 Jul 2015
project

Methodological Approaches for Rapid Antibody Discovery

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11 May 2015
team

Humoral Immunology

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22 Apr 2015
publication

Efficient generation of human IgA monoclonal antibodies

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21 Apr 2015
publication

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

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18 Feb 2015
publication

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

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07 Feb 2015
publication

Amplification of highly mutated human Ig lambda light chains from an HIV-1 infected patient

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18 Jan 2015
center

Center for Translational Science

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12 Dec 2014
publication

HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies

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17 Sep 2014
publication

Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies

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16 Sep 2014
publication

Antibody B cell responses in HIV-1 infection

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25 Aug 2014
publication

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

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13 Jun 2014
publication

[HIV-1 cell-to-cell transmission and broadly neutralizing antibodies]

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25 Nov 2013
publication

Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission

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30 Oct 2013
publication

Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

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16 Sep 2013
publication

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

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13 Sep 2013
publication

Antibodies in HIV-1 vaccine development and therapy

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03 Apr 2013
publication

HIV: Roadmaps to a vaccine

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28 Mar 2013
publication

Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization

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30 Oct 2012
publication

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

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24 Oct 2012
publication

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

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23 Jul 2012
publication

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

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30 Apr 2012
publication

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice

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04 Jan 2012
publication

Enhanced HIV-1 neutralization by antibody heteroligation

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02 Nov 2011
publication

Polyreactive antibodies in adaptive immune responses to viruses

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24 Oct 2011
publication

Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

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08 Sep 2011
publication

Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses

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14 Jul 2011
publication

Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding

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30 Sep 2010
publication

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

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02 Aug 2010
publication

Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness

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10 Mar 2010
publication

Anti-gp41 antibodies cloned from HIV-infected patients with broadly neutralizing serologic activity

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10 Aug 2009
publication

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

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01 May 2009
publication

ELISA testing of anti-desmoglein 1 and 3 antibodies in the management of pemphigus

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15 Mar 2009
publication

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

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25 Dec 2008
publication

A method for identification of HIV gp140 binding memory B cells in human blood

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14 Sep 2008
publication

Detection and characterization of anti-envoplakin linker autoantibodies in paraneoplastic pemphigus using specific bead-based assay

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19 Jun 2008
publication

B-cell depletion immunotherapy in pemphigus: effects on cellular and humoral immune responses

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10 Mar 2008
publication

Expression of pemphigus-autoantigen desmoglein 1 in human thymus

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01 Aug 2007
publication

A single cycle of rituximab for the treatment of severe pemphigus

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01 Nov 2006
publication

Immunogenetics of pemphigus: an update

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01 Nov 2006
publication

A truncated alternative spliced isoform of human desmoglein 1 contains a specific T cell epitope binding to the pemphigus foliaceus-associated HLA class II DRbeta1*0102 molecule

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01 Sep 2006
publication

Proteomic analysis of the autoantibody response following immunization with a single autoantigen

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01 Jun 2005
publication

Genetic factors in pemphigus

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01 Mar 2005
publication

[Molecular advances in pathogenesis of autoimmune blistering skin diseases]

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01 Jul 2004
publication

Anti-desmoglein 1 antibodies in Tunisian healthy subjects: arguments for the role of environmental factors in the occurrence of Tunisian pemphigus foliaceus

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01 Feb 2003
publication

Paraneoplastic pemphigus is associated with the DRB1*03 allele

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