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  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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© Research
Event

Groupe de Reflexion SIDA (GRS) seminar: “Functional and structural studies of the T cell response against two major human viruses: HIV-1 and SARS-CoV-2”

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
30
Aug 2022
Time
12:00:00
Address
Building: Lwoff Room: 14
Location
2022-08-30 12:00:00 2022-08-30 13:00:00 Europe/Paris Groupe de Reflexion SIDA (GRS) seminar: “Functional and structural studies of the T cell response against two major human viruses: HIV-1 and SARS-CoV-2” Pr. Stéphanie GRAS (La Trobe University, Australia) will discuss the structural determinants that condition T cell responses directed at SARS-CoV-2. Pr. Gras is a specialist of T cell receptor  (TCR)  structure and has recently […] Lisa Chakrabarti lisa.chakrabarti@pasteur.fr

About

Pr. Stéphanie GRAS (La Trobe University, Australia) will discuss the structural determinants that condition T cell responses directed at SARS-CoV-2. Pr. Gras is a specialist of T cell receptor  (TCR)  structure and has recently elucidated a mechanisms involved in the cross-reactivity of SARS-CoV-2-specific CD8+ T cells for seasonal coronaviruses (Lineburg KE et al. Immunity, 2021).

In the second part of the seminar, Demetra CHATZILEONTIADOU, postdoctoral fellow in the GRAS laboratory, will present recent findings on the structure of HIV-specific TCRs. She will discuss how the structural plasticity of TCRs that enable the recognition of the same HIV epitope presented by multiple HLA-DR alleles.

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