About
The overall goal of our research is to better understand the fundamental mechanisms behind inter-individual differences in immune responses, and apply these discoveries to relevant clinical questions. To do this we use cellular mechanistic models, population immunology cohorts, and experimental clinical studies in infection and autoimmunity. By working closely with clinical collaborators we hope that our research will help to develop new patient management
Members
Groups
Group

Group : Milieu Intérieur

Darragh Duffy
Former Members
2000
2000
Name
Position
2015
2019
LLIBRE SERRADELL Alba
Post doc
2018
2018
BOCQUENTIN Juliette
Master student
2019
2019
GOEL Naina
Master student
2020
2020
OMRAN Maha
Master student
2021
2021
BELOV Artem
Master student
2016
2021
POSSEME Céline
PhD student / Post-doc
2022
2022
ZUCCO Adrian
undergraduate student
Transversal Project
Fundings
Publications
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2022Rhesus negative males have an enhanced IFNγ-mediated immune response to influenza A virus., Genes Immun 2022 Apr; (): .
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2022Activation of NLRP3 Inflammasome in the Skin of Patients with Systemic and Cutaneous Lupus Erythematosus., Acta Derm Venereol 2022 Mar; (): .
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2022Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes., Genome Med 2022 Mar; 14(1): 28.
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2022Efficacy and tolerance of corticosteroids and methotrexate in patients with juvenile dermatomyositis: a retrospective cohort study., Rheumatology (Oxford) 2022 Feb; (): .
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2022Defects in mucosal immunity and nasopharyngeal dysbiosis in HSC transplanted SCID patients with IL2RG/JAK3 deficiency., Blood 2022 02; (): .
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2022Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old., EBioMedicine 2022 Feb; 76(): 103852.
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2022The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies., Res Sq 2022 Jan; (): .
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2021Human immune diversity: from evolution to modernity., Nat Immunol 2021 Dec; 22(12): 1479-1489.
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2021Type I interferon response and vascular alteration in chilblain-like lesions during the COVID-19 outbreak., Br J Dermatol 2021 12; 185(6): 1176-1185.
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2021Severe COVID-19 is associated with hyperactivation of the alternative complement pathway., J Allergy Clin Immunol 2021 Nov; (): .
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