Lluis Quintana-Murci

21 Members

Protected: Pasteur Human Genome

Thomas Bourgeron (PI)

There is no excerpt because this is a protected post.

7 Members

ERC-2011-StG EVOIMMUNOPOP

Human Evolutionary Immunogenomics: population genetic variation in immune responses Recent genome-wide association studies have successfully identified rare and common variants that correlate with complex traits. However, they have provided us with little insight into […]

4 Members

The footprints of natural selection in the human genome

The wide range of phenotypic variation in human populations may reflect distinctive processes of selection/adaptation to variable environmental conditions (e.g. climate, pathogens, nutritional resources). The advent of genome-wide datasets allows testing different hypotheses concerning […]

2 Members

Evolutionary genomics of innate immunity in humans

Inferences concerning the action of selection provide a powerful tool for predicting regions of the genome associated with disease. As infectious diseases exert strong selection pressures, the identification of immunity-related genes targeted by selection […]

5 Members

Genetics of gene expression in immunity to infection

By integrating cutting-edge knowledge and technology in the fields of genomics, population genetics, immunology and bioinformatics, our aim is to establish a thorough understanding of how variable the human immune response is in the […]

3 Members

Human lifestyle and genetic and epigenetic variation

The most important cultural innovation witnessed by modern humans has probably been the transition from a hunter-gatherer nomadic mode of subsistence to an agricultural sedentary lifestyle. This transition occurred in many parts of the […]