Lluis Quintana-Murci

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Human Evolutionary Immunogenomics: population genetic variation in immune responsesRecent genome-wide association studies have successfully identified rare and common variants that correlate with complex traits. However, they have provided us with little insight into the […]

The wide range of phenotypic variation in human populations may reflect distinctive processes of selection/adaptation to variable environmental conditions (e.g. climate, pathogens, nutritional resources). The advent of genome-wide datasets allows testing different hypotheses concerning […]

Inferences concerning the action of selection provide a powerful tool for predicting regions of the genome associated with disease. As infectious diseases exert strong selection pressures, the identification of immunity-related genes targeted by selection […]

By integrating cutting-edge knowledge and technology in the fields of genomics, population genetics, immunology and bioinformatics, our aim is to establish a thorough understanding of how variable the human immune response is in the […]

The most important cultural innovation witnessed by modern humans has probably been the transition from a hunter-gatherer nomadic mode of subsistence to an agricultural sedentary lifestyle. This transition occurred in many parts of the […]

The LISTERIAGEN project aims to identify host genetic factors associated with susceptibility to listeriosis.