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  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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© Research
Scientific Fields
Diseases
Organisms
Applications
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Projects

Project
Ongoing
3 Members

TYK2 variants in cytokine signaling and autoimmune diseases

Sandra Pellegrini (PI)

TYK2 belongs to the Janus/JAK family of protein tyrosine kinases and is involved in signaling of immunoregulatory cytokines (type I and type III IFNs, IL-6, IL-10 and IL-12 families) that contribute to a balanced […]
Project
Ongoing
2 Members

Fine-tuning of IFN-I response by USP18

Sandra Pellegrini (PI)

The type I IFN system needs to be regulated not only at the level of its production, but also at the level of responses. We have shown that cells that have responded to IFN-I […]

Publications

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