Enteric Bacterial Pathogens

5 Members

The SARA project: Surveillance of Antibiotic Resistance in Africa, an integrative project of the Pasteur Network

Sylvain Brisse (PI)

Antibiotic resistance is one of the most serious threats to global health. The misuse of antimicrobials in humans and animals accelerates this process, and the consequences for human health are particularly severe in low-resource […]

5 Members

Evolutionary history of the classical biotype of Vibrio cholerae O1

The classical biotype of Vibrio cholerae O1 was responsible for the first six cholera pandemics, but is relatively unknown, with only 20 genome sequences (50% of which come from the same geographic area) for […]

6 Members

Genomic insights into the 2016-2017 cholera epidemic in Yemen

Cholera is thought by many to be a disease of the Victorian era. However, Yemen has recently experienced one of the largest ever cholera epidemics. The first cases were declared in September 2016, and […]

3 Members

Historical antibiotic-resistant populations of S. enterica serotype Typhimurium

Little is known about the emergence and spread of the first antibiotic-resistant populations. It is believed, for example, that the very common penicillinase gene, blaTEM-1, discovered for the first time in E. coli in Greece […]

8 Members

Oxford Nanopore sequencing for detection and surveillance of pathogens

Sylvain Brisse (PI)

This project intends to share expertise, developments, equipement and bioinformatics tools to apply Oxford Nanopore Technology sequencing to the detection, diagnostic and characterization of pathogens of public health importance. It corresponds to a collaboration […]

4 Members

Phylodynamics of Vibrio cholerae O1 in Africa (1970-2014)

In 1970, ten years after the beginning of the 7th pandemic (Indonesia, 1961), cholera hit Africa, where it has remained entrenched. Three decades later, the reported incidence of indigenous cholera in sub-Saharan Africa was […]

16 Members

Phylogenomics of Shiga’s epidemic dysentery bacillus (Shigella dysenteriae type 1)

The agent of epidemic dysentery, the bacterium Shigella dysenteriae type 1, was isolated in Japan in 1897 by Dr Kyoshi Shiga during a massive epidemic of bloody diarrhea that caused 20,000 deaths over a […]

19 Members

Escherichia coli-Shigella-Salmonella

The Unit includes two National Reference Centers (CNR) and a WHO Collaborating Center. Our interests are the population dynamics of bacterial enteric pathogens such Salmonella, Shigella/Escherichia coli and Vibrio, with a special focus on […]

Transversal Project

Fighting Antibiotic Resistance

Antibiotics are highly efficient drugs to kill pathogenic bacteria with low side effects. For more than 70 years, the massive use of these miracle drugs has saved millions of human and animal lives. Unfortunately […]

The institut Carnot Pasteur MS

Carnot, label of excellence Founded in 2006, the Carnot Label, granted by the French government, was designed to develop partnership-based research, meaning research conducted by public laboratories in partnership with socio-economic players, primarily industry […]

LabEx IBEID – Integrative Biology of Emerging Infectious Diseases

Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart, is to develop a structure to anticipate and tackle emerging infectious diseases (EIDs). […]

Tools

Tool

4 Members

Salmonella CRISPR Typing