Evolutionary history of the classical biotype of Vibrio cholerae O1
The classical biotype of Vibrio cholerae O1 was responsible for the first six cholera pandemics, but is relatively unknown, with only 20 genome sequences (50% of which come from the same geographic area) for […]
Genomic insights into the 2016-2017 cholera epidemic in Yemen
Cholera is thought by many to be a disease of the Victorian era. However, Yemen has recently experienced one of the largest ever cholera epidemics. The first cases were declared in September 2016, and […]
Oxford Nanopore sequencing for detection and surveillance of pathogens
This project intends to share expertise, developments, equipement and bioinformatics tools to apply Oxford Nanopore Technology sequencing to the detection, diagnostic and characterization of pathogens of public health importance. It corresponds to a collaboration […]
Phylodynamics of Vibrio cholerae O1 in Africa (1970-2014)
In 1970, ten years after the beginning of the 7th pandemic (Indonesia, 1961), cholera hit Africa, where it has remained entrenched. Three decades later, the reported incidence of indigenous cholera in sub-Saharan Africa was […]
Phylogenomics of Shiga’s epidemic dysentery bacillus (Shigella dysenteriae type 1)
The agent of epidemic dysentery, the bacterium Shigella dysenteriae type 1, was isolated in Japan in 1897 by Dr Kyoshi Shiga during a massive epidemic of bloody diarrhea that caused 20,000 deaths over a […]
The Unit includes two National Reference Centers (CNR) and a WHO Collaborating Center. Our interests are the population dynamics of bacterial enteric pathogens such Salmonella, Shigella/Escherichia coli and Vibrio, with a special focus on […]
2019Genomic insights into the 2016-2017 cholera epidemic in Yemen, Nature 2019 Jan;.
2017Integrated view of Vibrio cholerae in the Americas, Science 2017 11;358(6364):789-793.
2017Genomic history of the seventh pandemic of cholera in Africa, Science 2017 11;358(6364):785-789.
2016Erratum: Global phylogeography and evolutionary history of Shigella dysenteriae type 1, Nat Microbiol 2016 10;1(11):16209.
2016Global phylogeography and evolutionary history of Shigella dysenteriae type 1, Nat Microbiol 2016 03;1:16027.
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