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About

The Ecology and Emergence of Arthropod-borne Pathogens (EEAP) Unit is an UMR Institut Pasteur-CNRS and an USC Institut Pasteur-INRAE that focuses on vector-borne diseases by studying two groups of vectors in particular: mosquitoes and ticks. ~60% of emerging infectious diseases are zoonotic and most emerging infectious disease events over the past few decades have been caused by zoonoses. Arthropod-borne pathogens are particularly important, causing some of the most dramatic outbreaks that have occurred during the last 25 years. In addition to mosquito-borne pathogens, tick-borne pathogens pose a considerable risk for transmission of zoonoses. In the current context of climate change, land use modifications and urban greening, the epidemiology of arthropod-borne pathogens is altering. At the community scale, our group works on quantifying the zoonotic risk associated with environmental changes and ascertaining the underlying key features behind spill-over events, with a particular focus on arthropod-borne RNA viruses, and with the ultimate objectives of developing effective monitoring and control strategies. At the individual level, we continue our studies on vaccinology and host immune responses to infection, extending our current work on dengue and Zika virus infection to address that of the short and long-term human immune responses to Rift Valley Fever and Crimean-Congo Haemorrhagic Fever viruses.

Former Members

liste anciens membres GFMI

2000
2000
Name
Position
2011
2014
Olivier Telle
Postdoc
2011
2014
Laura Grange
PhD Student
2012
2014
Worachart Lert-Itthiporn
PhD Student
2012
2017
Etienne Simon-Lorière
Researcher expert
2012
2018
Christian Roussilhon
Research expert
2013
2015
Chalisa Louicharoen
Postodc
2013
2015
Audrey Grant
Postdoc
2013
2013
Chloé Colas
Graduate Student
2013
2017
Iryna Nikolayeva
PhD Student
2013
2014
Ingfar Soontarawirat
PhD Student
2014
2014
Diana Saravia
Graduate Student
2014
2015
Marion Barbet
PhD Student apprentice
2014
2014
Anne-Claire Andries
PhD Student
2014
2015
Ingfar Soontarawirat
PhD Student
2014
2017
Matthieu Prot
Technician
2014
2018
Marisa Oliveira
PhD Student
2014
201
Diana Saravia
Graduate Student
2014
2014
Wilawan Chan Inn
PhD Student
2015
2020
Noémie Courtejoie
PhD Student
2015
2020
Yoann Teissier
PhD Student
2015
2016
Sabine Duchatelet
Postdoc
2015
2017
Hubert Buczkowski
Postdoc
2015
2018
Jessy Marlène Goupeyou Youmsi
PhD Student
2015
2017
Stéphane Gangnard
Postdoc
2015
2017
Felix Giovanni Delgado Tiria
Postodc
2015
2020
Olivier Bomme
Technician
2016
2016
Thiery Nirina Jean Jose Nepomichene
PhD Student
2016
2019
Marina Penova
PhD Student
2016
2017
Maxime Chazal
Technician
2016
2016
Julien Dessap
Graduate Student
2016
2016
Fumihiko Matsuda
Invited Researcher
2016
2016
Maria Celeste Toress
Graduate Student
2016
2017
Fanny Koeth
Graduate Student apprentice
2016
2018
Bernard Cazelles
Professor UPMC
2016
2017
Kwansiri NINPAN
Invited researcher
2017
2021
Benjamin Vguyen-Van-Yen
PhD Student
2017
2018
Lucia Etheve
Undergraduate Student
2018
2018
Clovis Nicodeme Gatsi
Undergraduate Student apprentice
2017
2020
Majoline Tchioffo Tsapi
Postdoc
2017
2018
Louis Lebreton
Pharmacist
2017
2017
Pau Rodo de Yebra
Graduate Student
2017
2017
Philippe Travers
Graduate Student
2018
2018
Seydou Bâ Diallo
Graduate Student
2018
2019
Suganya Yongkiettrakul
Visiting Scientist
2019
2019
Nihad Bourqia
Graduate Student
2019
2019
Rojina Karki
Graduate Student
2019
2019
Andrea Lavarello Schettini
Graduate Student
2019
2020
Silvia Vidal
Invited researcher
2019
2019
Edward English
Graduate Student
2019
2019
Garima Joshi
Graduate Student
2019
2021
Tsarasoa Andrianinarivomanana
PhD Student
2019
2020
Pavlos Papadoulos
Graduate Student
2019
2019
Evelina Stastna
Graduate Student
2020
2020
Okechukwu Ochulor
Graduate Student
2020
2020
Rafael Deo Estanislao
Graduate Student
2020
2020
Stefania Porcelli
Graduate Student
2021
2021
Adèle Lefevre
Graduate Student
2021
2021
Bastien Enjalbert
Graduate Student
2021
2021
Nour El Hachem
Graduate Student
2021
2021
Léa Partaux
Graduate Student
2021
2021
Anis Ait Ali Yahia
Graduate Student
2022
2022
Ruben Ayala
PhD Student
2022
2022
Nileesh Gunalan
Graduate Student
2014
2022
Catherine Bourgouin
Head of group
2014
2022
Nicolas Puchot
Technician
2021
2022
Laura Goncalvez Pereira
Graduate Student
2016
2022
Marie-Thérèse Lecoq
Technician
2022
2022
Jean-Elie Cluzel
Technician
2021
2022
Emma Bezot
Graduate Student
2022
2023
Alexandre Cébeillac
Postdoct
2023
2023
Milos NIKOLIC
Master2
2023
2023
Prince Tardeh
licence
2024
2024
Margot Kowalik
BTS 1ère année
2024
2024
Tania Levitan
école d'ingénieur
2024
2024
Mila Noré
Master 1
2024
2024
Evan Bouton
master 2
2024
2024
Alexiane Boyfini
BTS 1ère année
2025
2025
Margot Kowalik
BTS 2ème année
2025
2025
Appoline Charron
prépa ingénieur
Show all

Projects

Project
Completed
4 Members

Microbiological monitoring: new horizons for tick-borne diseases

Sarah Bonnet (PI)

Sorry, this entry is only available in FR.
Project
Ongoing
5 Members

PREPARE-TID: Pipeline for Rapid Diagnostics of Emergency Transboundary Infectious Diseases

PREPARE-TID: Pipeline for Rapid Diagnostics of Emergency Transboundary Infectious Diseases (PI)

Sorry, this entry is only available in FR.
Project
Ongoing
3 Members

He-Farm: Healthy environmental-friendly and resilient farm to fork

He-Farm: Healthy environmental-friendly and resilient farm to fork (PI)

Sorry, this entry is only available in FR.
Project
Ongoing
3 Members

BIOMATICK: Identification of biomarkers of tick bite exposure for both humans and animals

Sarah Bonnet (PI)

Sorry, this entry is only available in FR.
Project
Ongoing
8 Members

Exploring mechanisms of TBEV infection and transmission in mouse-tick models

Caroline Manet (PI)

Tick-borne encephalitis virus (TBEV) is a flavivirus transmitted primarily by Ixodes ricinus ticks and is an emerging public health concern in Europe, including France, where cases are rising despite available vaccines. Each year, TBEV […]
Project
Ongoing
5 Members

Study of immune crosstalk in COVID-19 COVIMUNE

Anavaj Sakuntabhai (PI)

Our overall goal is to understand the cellular and molecular aspects of immune response to SARS-CoV-2 virus in terms of activation of over-reactive immunity and induction of immune protection. COVIMUNE is designed to target […]
Project
Ongoing
8 Members

Host genetic susceptibility to Zika virus

Caroline Manet (PI)

Zika virus is an arbovirus responsible for recent epidemics in Polynesia and in the Americas. Clinical descriptions range from mild flu-like syndromes to rare but severe neurological complications such as Guillain-Barré syndrome and encephalitis […]
Project
Ongoing
3 Members

miRNA involvement in resistance to infection by Dengue virus : miRNA transcriptome on monocytes of individuals “Susceptible” or “Resistant” following in vitro infection by DENV2

Isabelle Casademont (PI)

We performed miRNome on monocytes from healthy donors living in Bangkok, previously checked for their antibodies against DENV. We hypothesized that individuals without antibodies against any serotype of DENV may represent a DENV-resistant population, […]
Project
Ongoing
2 Members

Analyzing SKAP2 Interactome to pinpoint its Functions

Jean-François Bureau (PI)

The SRC Kinase Adaptor Phosphoprotein 2 (SKAP2), a broadly expressed protein recruiting protein partners to specific subcellular domains, plays a central role in multiple processes including TGFb response, integrin signalling, and cell migration. It […]
Project
Ongoing
2 Members

T cell immunity to dengue virus infection in transgenic mice expressing human HLA molecules

Claude Roth (PI)

Based on the recent identification of the non-structural proteins NS3, NS4B and NS5 of dengue virus (DENV) as the main targets for T cell responses in humans, we have designed a minimal DENV antigen, […]
Project
Ongoing
4 Members

Effect of host-parasite interaction on the outcome of malaria infection

Anavaj Sakuntabhai (PI)

It is well accepted that the outcome of infection in malaria depends upon interaction between the human host and Plasmodium spp. This is the result of forces of selection and escape acting on the […]
Project
Completed
7 Members

DENFREE consortium – Dengue Framework for Resisting Epidemics in Europe

Anavaj Sakuntabhai (PI)

The main objective of the programme is to focus on finding key factors determining dengue transmission and dynamics in order to develop new tools and strategies for controlling dengue transmission. We will estimate the […]
Project
Completed
5 Members

LeiSHield – A new collaborative action to determine prevalence, anticipate emergence and assess urbanization of cutaneous and visceral leishmaniasis in LeishRIIP partner countries

Gérald Spaeth (PI)

Protozoan parasites of the genus Leishmania generate severe human diseases termed Leishmaniases. Due to their frequency and the severity of certain clinical forms, these diseases represent a major public health problem and limit the […]

Transversal Project

Center for Vaccinology and Immunotherapy (CVI)

Vaccines and immunotherapies have had a major positive impact on public health world-wide through disease prevention and treatment that can be measured in millions of lives saved. Despite the successes, we still face major […]

Emerging Infectious Diseases

Ever since its very early days, the Institut Pasteur has been committed to tackling emerging infections, and its work has left an extraordinary legacy. Many emerging infectious diseases are zoonoses, in which an animal […]

INCEPTION – Institut Convergence for the study of Emergence of Pathology Through Individuals and Populations

INCEPTION Goal The Inception aims to develop a core structure to mobilize data resources, numerical sciences, and fundamental experimental biology in various health issues (Official website here: https://www.inception-program.fr/en). The inception program uses Integrative Biology, […]

LabEx Milieu Intérieur

The Milieu Intérieur project provides insight into the core of human diversity by dissecting the interplay between genetics and environment and their impact on the immune system. The Milieu Intérieur Project While the immune […]

LabEx IBEID – Integrative Biology of Emerging Infectious Diseases

Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart and currently coordinated by Carla Saleh and Philippe Bastin, is to develop a […]

Patents

A Zika virus chimeric polyepitope comprising non-structural proteins and its use in immunogenic composition (EP 17 306553.3)

The present invention is directed to a Zika virus (ZIKV) chimeric polyepitope composed of fragments of structural and non-structural proteins and its use in an immunogenic composition. The present invention provides means, in particular […]

A dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection (E14305984.8)

The present invention is directed to a dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection. The present invention provides means, in […]

Publications

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Contact

Phone: 33 1 44 38 91 03 Email: anavaj@pasteur.fr Address: 28 Rue du Docteur Roux, 75015 Paris, France