• 2022
  Marie Flamme, Steven Hanlon, Irene Marzuoli, Kurt Püntener, Filippo Sladojevich and Marcel Hollenstein*, Evaluation of 3′-phosphate as a transient protecting group for controlled enzymatic synthesis of DNA and XNA oligonucleotides, Commun. Chem. 2022, 5, 68.
• 2022
  Sabat, N.; Zhou, W.; Gandon, V.; Guinchard, X.; Vincent, G., Unbiased C3-Electrophilic Indoles: Triflic Acid Mediated C3-Regioselective Hydroarylation of N-H Indoles, Angew. Chem. Int. Ed. 2022, 61, e2022044.
• 2022
  Zhang, Z.; Sabat, N.; Frison, G.; Marinetti, A.; Guinchard, X., Enantioselective Au(I)-Catalyzed Multicomponent Annulation via Tethered Counterion-Directed Catalysis, ACS Catal. 2022, 12, 4046 - 4053.
• 2022
  Sabat, N.; Ouarti, A.; Migianu-Griffoni, E.; Lecouvey, M.; Ferraris, O.; Gallier, F.; Peyrefitte, C.; Lubin-Germain, N.; Uziel, J., Synthesis, antiviral and antitumor activities investigations of a series of Ribavirin C-nucleoside analogue prodrugs, Bioorg. Chem. 2022, 122, 105723.
• 2022
  Fabienne Levi-Acobas, Luke K. McKenzie, and Marcel Hollenstein*, Towards polymerase-mediated synthesis of artificial RNA–DNA metal base pairs, New J. Chem., 2022, 46, 4871-4876.
• 2022
  Soualmia, F.; Guillot, A.; Sabat, N.; Brewee, C.; Haumann, M.; Guinchard, X.; Benjdia, A.; Berteau, O., Biochemical and XAS investigation of TsrM, a B12-dependent Radical SAM Enzyme Catalyzing Non-radical reaction, Chem. Eur. J. 2022, 28, e2022006.
• 2022
  Luke K. McKenzie‡, Marie Flamme‡, Patrick S. Felder, Johannes Karges, Frederic Bonhomme, Albert Gandioso, Christian Malosse, Gilles Gasser* and Marcel Hollenstein*, A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy, RSC Chem. Biol., 2022, 3, 85-95.
• 2021
  Fabienne Levi-Acobas, Luke K. McKenzie, Marcel Hollenstein*, Polymerase-mediated synthesis of artificial RNA-DNA metal base pairs, ChemRxiv 2021, 10.26434/chemrxiv-2021-2d0h6.
• 2021
  Luke K. McKenzie, Marie Flamme, Patrick S. Felder, Johannes Karges, Frederic Bonhomme, Albert Gandioso, Christian Malosse, Gilles Gasser, Marcel Hollenstein, A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy, RSC Chemical Biology.
• 2021
  Luke K. McKenzie, Marie Flamme, Patrick S. Felder, Johannes Karges, Frederic Bonhomme, Albert Gandioso, Christian Malosse, Gilles Gasser*, Marcel Hollenstein*, A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy, ChemRxiv 2021, 10.33774/chemrxiv-2021-5n9xv.
• 2021
  Marie Flamme, Steven Hanlon, Hans Iding, Kurt Puentener, Filippo Sladojevich, Marcel Hollenstein*, Towards the enzymatic synthesis of phosphorothioate containing LNA oligonucleotides, Bioorg. Med. Chem. Lett. 48 (2021) 128242.
• 2021
  Sleiman D, Garcia PS, Lagune M, Loc'h J, Haouz A, Taib N, Röthlisberger P, Gribaldo S, Marlière P, Kaminski PA, A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes., Science 2021 04; 372(6541): 516-520.
• 2021
  Marie Flamme, Chiara Figazzolo, Gilles Gasser and Marcel Hollenstein∗, Enzymatic construction of metal-mediated nucleic acid base pairs, Metallomics, 2021, 13, mfab016.
• 2021
  Luke K. McKenzie, Roberto El-Khoury, James D. Thorpe, Masad J. Damha* and Marcel Hollenstein*, Recent progress in non-native nucleic acid modifications, Chem. Soc. Rev. 2021, 50, 5126–5164.
• 2021
  Tom Baladi, Jesper R. Nilsson, Audrey Gallud, Emanuele Celauro, Cécile Gasse, Fabienne Levi-Acobas, Ivo Sarac, Marcel R. Hollenstein, Anders Dahlén, Elin K. Esbjörner*, and L. Marcus Wilhelmsson*, Stealth Fluorescence Labeling for Live Microscopy Imaging of mRNA Delivery, J. Am. Chem. Soc. 2021, 143, 5413−5424.
• 2020
  Marie Flamme, Pascal Röthlisberger, Fabienne Levi-Acobas, Mohit Chawla, Romina Oliva, Luigi Cavallo, Gilles Gasser, Philippe Marlière, Piet Herdewijn, and Marcel Hollenstein*, Enzymatic Formation of an Artificial Base Pair Using a Modified Purine Nucleoside Triphosphate, ACS Chem. Biol. 2020, 15, 2872-2884.
• 2020
  Marie Flamme, Fabienne Levi‐Acobas, Susanne Hensel, Shuvankar Naskar, Pascal Röthlisberger, Ivo Sarac, Gilles Gasser, Jens Müller, Marcel Hollenstein*, Enzymatic Construction of Artificial Base Pairs: The Effect of Metal Shielding, ChemBioChem 2020, 21, 3398-3409.
• 2020
  Milcendeau, P.; Sabat, N.; Ferry, A.; Guinchard, X., Gold-Catalyzed Enantioselective Functionalizations of Indoles, Org. Biomol. Chem. 2020, 18, 6006 – 6017.
• 2020
  Cheung YW, Röthlisberger P, Mechaly AE, Weber P, Levi-Acobas F, Lo Y, Wong AWC, Kinghorn AB, Haouz A, Savage GP, Hollenstein M*, Tanner JA*, , Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker., Proc. Natl. Acad. Sci. U.S.A. 2020 Jul; (): .
• 2020
  Tom Baladi, Jesper R. Nilsson, Audrey Gallud, Emanuele Celauro, Cécile Gasse, Fabienne Levi-Acobas, Ivo Sarac, Marcel Hollenstein, Anders Dahlen, Elin K. Esbjörner, Marcus Wilhelmsson*, Stealth fluorescence labeling for live microscopy imaging of mRNA delivery, BioxRiv, 2020, 172767 (doi: 10.1101/2020.07.01.172767).
• 2020
  John C. Chaput*, Piet Herdewijn*, Marcel Hollenstein*, Orthogonal Genetic Systems, ChemBioChem 2020, 21, 1408-1411.
• 2020
  Sabat, N.; Soualmia, F.; Retailleau, P.; Bendjdia, A.; Berteau, O.; Guinchard, X., Gold-Catalyzed Spirocyclization Reactions of N-propargyl Tryptamines and Tryptophanes in Aqueous Media, Org. Lett. 2020, 22, 4344 – 4349.
• 2020
  Pascal Röthlisberger, Fabienne Levi-Acobas, Christian J. Leumann, Marcel Hollenstein*, Enzymatic synthesis of biphenyl-DNA oligonucleotides, Biorg. Med. Chem. 2020, 28, 115487.
• 2020
  Diego Carnevale*, Marcel Hollenstein, and Geoffrey Bodenhausen, Self‐Assembly of DNA and RNA Building Blocks Explored by Nitrogen‐14 NMR Crystallography: Structure and Dynamics, ChemPhysChem 2020, 21, 1044-1051.
• 2020
  Nancy Soliman, Luke K. McKenzie, Johannes Karges, Emilie Bertrand, Mickaël Tharaud, Marta Jakubaszek, Vincent Guérineau, Bruno Goud, Marcel Hollenstein, Gilles Gasser * and Christophe M. Thomas *, Ruthenium-initiated polymerization of lactide: a route to remarkable cellular uptake for photodynamic therapy of cancer, Chem. Sci., 2020, 11, 2657-2663.
• 2019
  Marie Flamme, Pascal Röthlisberger, Fabienne Levi-Acobas, Mohit Chawla, Romina Oliva, Luigi Cavallo, Gilles Gasser, Philippe Marlière, Piet Herdewijn, and Marcel Hollenstein*, Enzymatic Formation of an Artificial Base Pair Using a Modified Adenine Nucleoside Triphosphate, ChemRxiv 2019, doi: 10.26434/chemrxiv.11427459.v1.
• 2019
  Sabat, N.; Migianu-Griffoni, E.; Tudela, T.; Lecouvey, M.; Kellouche, S.; Carreiras, F.; Gallier, F.; Uziel, J.; Lubin-Germain, N., Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin, Eur. J. Med. Chem. 2020, 188, 112009.
• 2019
  Fabienne Levi-Acobas, Pascal Röthlisberger, Ivo Sarac, Philippe Marlière, Piet Herdewijn, and Marcel Hollenstein*, On the Enzymatic Formation of Metal Base Pairs with Thiolated and pKa-Perturbed Nucleotides, ChemBioChem 2019, 20, 3032 – 3040.
• 2019
  M. M. Pichon, D. Hazelard, P. Compain, Metal-Free Deoxygenation of α-Hydroxy Carbonyl Compounds and Beyond, Eur JOC, 2019, 37, 6320-6332.
• 2019
  Fabienne Levi-Acobas, Adam Katolik, Pascal Röthlisberger, Thomas Cokelaer, Ivo Sarac, Masad J. Damha, Christian J. Leumann and Marcel Hollenstein*, Compatibility of 5-ethynyl-2’F-ANA UTP with in vitro selection for the generation of base-modified, nuclease resistant aptamers, Org. Biomol. Chem. 2019, 17, 8083 - 8087.
• 2019
  Marcel Hollenstein*, Nucleic acid enzymes based on functionalized nucleosides, Curr. Opin. Chem. Biol. 2019, 52, 93-101.
• 2019
  M. M. Pichon, F. Stauffert, A. Bodlenner, P. Compain, Tight-binding inhibition of jack bean α-mannosidase by glycoimidazole clusters, Org. Biomol. Chem., 2019, 17, 5801-5817.
• 2019
  Stella Diafa, Damien Evéquoz, Christian J. Leumann, and Marcel Hollenstein*, Synthesis and Enzymatic Characterization of Sugar-Modified Nucleoside Triphosphate Analogs, Methods Mol. Biol. 2019, 1973, 1-13.
• 2019
  MarieFlamme, Luke K McKenzie, IvoSarac, Marcel Hollenstein*, Chemical methods for the modification of RNA, Methods 2019, 161, 64-82.
• 2019
  Ivo Sarac, Marcel Hollenstein*, Terminal Deoxynucleotidyl Transferase in the Synthesis and Modification of Nucleic Acids, ChemBioChem 2019, 20, 860 – 871.
• 2019
  Pascal Röthlisberger, Fabienne Levi-Acobas, Ivo Sarac, Philippe Marlière, Piet Herdewijn, Marcel Hollenstein*, Towards the enzymatic formation of artificial metal base pairs with a carboxy-imidazole-modified nucleotide, J. Inorg. Biochem. 2019, 191, 154-163.
• 2018
  Pascal Röthlisberger, Fabienne Levi-Acobas, Ivo Sarac, Rémy Ricoux, Jean-Pierre Mahy, Piet Herdewijn, Philippe Marlière, Marcel Hollenstein*, Incorporation of a minimal nucleotide into DNA, Tetrahedron Lett. 2018, 59, 4241-4244.
• 2018
  Kyoung-Ran Kim, Pascal Röthlisberger, Seong Jae Kang, Kihwan Nam, Sangyoup Lee, Marcel Hollenstein, and Dae-Ro Ahn, Shaping Rolling Circle Amplification Products into DNA Nanoparticles by Incorporation of Modified Nucleotides and Their Application to In Vitro and In Vivo Delivery of a Photosensitizer, Molecules 2018, 23, 1833.
• 2018
  Hien Bao Dieu Thai, Fabienne Levi-Acobas, Soo-Young Yum, Goo Jang, Marcel Hollenstein and Dae-Ro Ahn, Tetrahedral DNAzymes for enhanced intracellular gene-silencing activity, Chem. Commun., 2018,54, 9410-9413 .
• 2018
  Marie Flamme, Emma Clarke, Gilles Gasser*, and Marcel Hollenstein*, Applications of Ruthenium Complexes Covalently Linked to Nucleic Acid Derivatives, Molecules, 2018, 23, 1515.
• 2018
  Sabat, N.; Poštová Slavětínská, L.; Klepetářová, B.; Hocek, M., C-H Imidation of 7-Deazapurines., ACS Omega. 2018, 3, 4674 – 4678.
• 2018
  Pascal Röthlisberger and Marcel Hollenstein*, Aptamer chemistry, Adv. Drug Deliv. Rev. 2018, 134, 3–21.
• 2018
  M. M. Pichon, F. Stauffert, L. G. Addante-Moya, A. Bodlenner, P. Compain, Metal-Free Iodine-Mediated Deoxygenation of Alcohols in the Position α to Electron-Withdrawing Groups, Eur. JOC, 2018, 13, 1538-1545.
• 2018
  Marcel Hollenstein*, DNA Synthesis by Primer Exchange Reaction Cascades, ChemBioChem, 2018, 19, 422-424.
• 2017
  Pascal Röthlisberger, Cécile Gasse,* and Marcel Hollenstein*, Nucleic Acid Aptamers: Emerging Applications in Medical Imaging, Nanotechnology, Neurosciences, and Drug Delivery, Int. J. Mol. Sci. 2017, 18, 2430.
• 2017
  Pascal Röthlisberger, Fabienne Levi-Acobas, Ivo Sarac, Bruno Baron, Patrick England, Philippe Marlière, Piet Herdewijn, and Marcel Hollenstein, Facile immobilization of DNA using an enzymatic his-tag mimic, Chem. Commun., 2017, 53, 13031-13034.
• 2017
  Sabat, N.; Smolén. S.; Nauš, P.; Perlíková. P.; Cebová. M.; Poštová Slavětínská, L.; Hocek, M., Synthesis of 2,6-Substituted-7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted-5-(Het)aryl-pyrrolo[2,3-d]pyrimidines, Synthesis. 2017, 49, 4623 – 4650.
• 2017
  D. Hazelard, M. L. Lepage, J. P. Schneider, M. M. Pichon, F. Massicot, P. Compain, Large Scale Synthesis of 2,3,4,6-Tetra-O-Benzyl-1-Deoxynojirimycin, Carbohydrates Chemistry: ProvenSyntheticMethods, Vol.4, 2017, 303-314.
• 2017
  S. Diafa, D. Evéquoz, C. J. Leumann, M. Hollenstein, Enzymatic Synthesis of 7’,5’-Bicyclo-DNA Oligonucleotides, Chem. Asian J. 2017, 12, 1347-1352.
• 2017
  Röthlisberger, P.; Fabienne Levi-Acobas, F.; Sarac, I.; Marlière, P.; Herdewijn, P.; Hollenstein, M., On the enzymatic incorporation of an imidazole nucleotide into DNA, Org. Biomol. Chem. 2017, 15, 4449-4455.
• 2017
  Pascal Röthlisberger, Fabienne Levi-Acobas, Marcel Hollenstein, New synthetic route to ethynyl-dUTP: A means to avoid formation of acetyl and chloro vinyl base-modified triphosphates that could poison SELEX experiments, Bioorg. Med. Chem. Lett. 2017, 27, 897-900.
• 2016
  Marcel Hollenstein, Masad J. Damha, Rolling circle amplification with chemically modified nucleoside triphosphates, Curr. Protoc. Nucleic Acid Chem. 2016, 67, 7.26.1-7.26.15.
• 2016
  Sabat, N.; Nauš, P.; Matyašovský, J.; Dziuba, D.; Poštová Slavetínská, L.; Hocek, M., Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions, Synthesis. 2016, 48, 1029 – 1045.
• 2016
  Sabat N, Poštová Slavětínská L, Klepetářová B, Hocek M, , C-H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7- and 9-Deazapurine-8-phosphonate Derivatives., J. Org. Chem. 2016, 81, 9507 – 9514.
• 2016
  F. Stauffert, M. L. Lepage, M. M. Pichon, D. Hazelard, A. Bodlenner, P. Compain, A Convenient, Gram-Scale Synthesis of 1-Deoxymannojirimycin, Synthesis, 2016, 48, 1177-1180.
• 2015
  Hollenstein M, DNA Catalysis: The Chemical Repertoire of DNAzymes, Molecules 2015;20(11):20777-804.
• 2015
  Sabat, N.; Poštová Slavětínská, L.; Klepetářová, B.; Hocek, M., Ir-catalyzed C–H silylations of phenyldeazapurines., Tetrahedron Lett. 2015, 49, 6860 – 6862.
• 2015
  Hollenstein M, Generation of long, fully modified, and serum-resistant oligonucleotides by rolling circle amplification, Org. Biomol. Chem. 2015 Oct;13(38):9820-4.
• 2015
  Diafa S, Hollenstein M, Generation of Aptamers with an Expanded Chemical Repertoire, Molecules 2015;20(9):16643-71.
• 2015
  Räz MH, Hollenstein M, Probing the effect of minor groove interactions on the catalytic efficiency of DNAzymes 8-17 and 10-23, Mol Biosyst 2015 May;11(5):1454-61.
• 2015
  Renders M, Miller E, Hollenstein M, Perrin D, A method for selecting modified DNAzymes without the use of modified DNA as a template in PCR, Chem. Commun. (Camb.) 2015 Jan;51(7):1360-2.
• 2014
  Sabat, N.; Klečka, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M., Direct C–H amination and C–H chloroamination of 7-deazapurines., RSC Adv. 2014, 4, 62140 – 62143.
• 2014
  Hollenstein M, Leumann CJ, Synthesis and biochemical characterization of tricyclothymidine triphosphate (tc-TTP), Chembiochem 2014 Sep;15(13):1901-4.
• 2014
  Hollenstein M, Smith CC, Räz M, Nucleoside triphosphates–from synthesis to biochemical characterization, J Vis Exp 2014;(86).
• 2013
  Hollenstein M, Deoxynucleoside triphosphates bearing histamine, carboxylic acid, and hydroxyl residues–synthesis and biochemical characterization, Org. Biomol. Chem. 2013 Aug;11(31):5162-72.
• 2013
  Hollenstein M, Hipolito CJ, Lam CH, Perrin DM, Toward the combinatorial selection of chemically modified DNAzyme RNase A mimics active against all-RNA substrates, ACS Comb Sci 2013 Apr;15(4):174-82.
• 2012
  Hollenstein M, Nucleoside triphosphates–building blocks for the modification of nucleic acids, Molecules 2012;17(11):13569-91.
• 2012
  Hollenstein M, Synthesis of deoxynucleoside triphosphates that include proline, urea, or sulfonamide groups and their polymerase incorporation into DNA, Chemistry 2012 Oct;18(42):13320-30.
• 2012
  Hollenstein M, Wojciechowski F, Leumann CJ, Polymerase incorporation of pyrene-nucleoside triphosphates, Bioorg. Med. Chem. Lett. 2012 Jul;22(13):4428-30.
• 2011
  Lam CH, Hipolito CJ, Hollenstein M, Perrin DM, A divalent metal-dependent self-cleaving DNAzyme with a tyrosine side chain, Org. Biomol. Chem. 2011 Oct;9(20):6949-54.
• 2011
  Hipolito CJ, Hollenstein M, Lam CH, Perrin DM, Protein-inspired modified DNAzymes: dramatic effects of shortening side-chain length of 8-imidazolyl modified deoxyadenosines in selecting RNaseA mimicking DNAzymes, Org. Biomol. Chem. 2011 Apr;9(7):2266-73.
• 2011
  Hollenstein M, Expanding the catalytic repertoire of DNAzymes by modified nucleosides, Chimia (Aarau) 2011;65(10):770-5.
• 2009
  Hollenstein M, Hipolito CJ, Lam CH, Perrin DM, A DNAzyme with three protein-like functional groups: enhancing catalytic efficiency of M2+-independent RNA cleavage, Chembiochem 2009 Aug;10(12):1988-92.
• 2009
  Hollenstein M, Hipolito CJ, Lam CH, Perrin DM, A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M2+), Nucleic Acids Res. 2009 Apr;37(5):1638-49.
• 2008
  Hollenstein M, Hipolito C, Lam C, Perrin D, In vitro selection of a DNAzyme with three modified nucleotides, Nucleic Acids Symp Ser (Oxf) 2008;(52):73-4.
• 2008
  Hollenstein M, Hipolito C, Lam C, Dietrich D, Perrin DM, A highly selective DNAzyme sensor for mercuric ions, Angew. Chem. Int. Ed. Engl. 2008;47(23):4346-50.
• 2005
  Hollenstein M, Leumann CJ, Fluorinated olefinic peptide nucleic acid: synthesis and pairing properties with complementary DNA, J. Org. Chem. 2005 Apr;70(8):3205-17.
• 2003
  Hollenstein M, Leumann CJ, Synthesis and incorporation into PNA of fluorinated olefinic PNA (F-OPA) monomers, Org. Lett. 2003 May;5(11):1987-90.
• 2003
  Hollenstein M, Gautschi D, Leumann CJ, Fluorinated peptide nucleic acid, Nucleosides Nucleotides Nucleic Acids 2003 May-Aug;22(5-8):1191-4.
• 2000
  D. Franz, M. Hollenstein, Ch. Hollenstein, Diborane nitrogenrammonia plasma chemistry investigated by infrared absorption spectroscopy, Thin Solid Films 2000, 379, 37-44.