Darragh Duffy

Contexte et objectifs de l’étude PERT-SEVERE II La coqueluche est une infection bactérienne respiratoire, très contagieuse et d’évolution longue. Elle peut être grave chez le petit nourrisson, mais nous ne comprenons pas bien les […]

Hidradenitis Suppurativa (HS), also known as Verneuil’s disease and acne inversa, is an incurable skin disease manifesting as recurrent, invalidating abscesses. In addition to causing intense pain, HS is commonly associated with disability, depression […]

Rationnel La polypose adénomateuse familiale se manifeste par l’apparition dans l’intestin de nombreuses excroissances dénommées polypes adénomateux et susceptibles d‘évoluer en cancers en l’absence de prise en charge. Il s’agit d’une maladie génétique, le […]

Biomarker discovery We are interested in the discovery of biomarkers that can be used to guide the clinical management of patients, and can also inform us about basic disease pathogenesis. The lab’s interest in […]

Systems approaches for the study of immune signaling pathways have been traditionally based on selected purified cell types or cultured cell lines. However, in vivo responses involve the coordinated action of multiple cell types, […]

The objective of our project is to establish feasibility for a new generation of in vitro diagnostic (IVDs) tools, applied to proof-of-concept studies in Mycobacterium tuberculosis (MTB) infected persons and patients with TB disease. […]