Darragh Duffy leads the Translational Immunology unit at the Institut Pasteur, Paris and is co-coordinator of the LabEx Milieu Interieur project. The overall goal of his research is to better understand the fundamental mechanisms behind inter-individual differences in immune responses, and apply these discoveries to relevant clinical questions. To do this they use cellular mechanistic models, population immunology cohorts, and experimental clinical studies in infection and autoimmunity. They work closely with clinical collaborators with the goal that the research findings will help to develop new patient management strategies. For fundamental questions related to understanding immune variability they apply systems immunology approaches to diverse phenotypes and integrate with genetic and environmental factors.
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10th HKU-Pasteur Immunology Course: December 2-15, 2018
‘Quantitative Immunology’ will be the theme of the 10th anniversary of the HKU-Pasteur Immunology Course. We will explore the ongoing transition from reductionist studies, based on the application of genetic approaches in animal models, […]
2018-12-02 09:00:00
2018-12-15 18:00:00
Europe/Paris
10th HKU-Pasteur Immunology Course: December 2-15, 2018
‘Quantitative Immunology’ will be the theme of the 10th anniversary of the HKU-Pasteur Immunology Course. We will explore the ongoing transition from reductionist studies, based on the application of genetic approaches in animal models, […]
HKU-Pasteur Research Centre, Hong Kong
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2025IFN-α levels correlate with muscle disease activity only in juvenile dermatomyositis patients with anti-MDA5+ autoantibodies., Rheumatology (Oxford) 2025 Oct; (): .
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2025Dazukibart for the treatment of severe TIF1γ-positive juvenile dermatomyositis., J Eur Acad Dermatol Venereol 2025 Sep; (): .
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2025Altered DNA methylation of the ABO gene is associated with differential plasma levels of von willebrand factor and E-selectin., Transfusion 2025 Sep; 65(9): 1693-1706.
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2025Impaired cytotoxic function and exhausted phenotype of natural killer cells in VEXAS syndrome., Blood 2025 Jul; (): .
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2025Enhanced TLR7-dependent production of type I interferon by pDCs underlies pandemic chilblains., J Exp Med 2025 Jul; 222(7): .
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2025Steroid hormone levels vary with sex, aging, lifestyle, and genetics, Science Advances , 2025, 11 (13), pp.eadu6094. ⟨10.1126/sciadv.adu6094⟩.
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2025Autoinflammatory encephalopathy due to PTPN1 haploinsufficiency: a case series., Lancet Neurol 2025 Mar; 24(3): 218-229.
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2025Efficacy of Ruxolitinib in Severe Pediatric Intra-Alveolar Hemorrhages Unrelated to COPA Mutations., Pediatr Pulmonol 2025 Jan; 60(1): e27481.
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2025Ultrasensitive interferons quantification reveals different cytokine profile secretion in inflammatory myopathies and can serve as biomarkers of activity in dermatomyositis., Front Immunol 2025 ; 16(): 1529582.
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2025Comment on: Inflammatory plasma protein levels are elevated years before sarcoidosis diagnosis: a nested case-control study in Sweden., Eur Respir J 2025 Jan; 65(1): .
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