Darragh Duffy leads the Translational Immunology unit at the Institut Pasteur, Paris and is co-coordinator of the LabEx Milieu Interieur project. The overall goal of his research is to better understand the fundamental mechanisms behind inter-individual differences in immune responses, and apply these discoveries to relevant clinical questions. To do this they use cellular mechanistic models, population immunology cohorts, and experimental clinical studies in infection and autoimmunity. They work closely with clinical collaborators with the goal that the research findings will help to develop new patient management strategies. For fundamental questions related to understanding immune variability they apply systems immunology approaches to diverse phenotypes and integrate with genetic and environmental factors.
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10th HKU-Pasteur Immunology Course: December 2-15, 2018
‘Quantitative Immunology’ will be the theme of the 10th anniversary of the HKU-Pasteur Immunology Course. We will explore the ongoing transition from reductionist studies, based on the application of genetic approaches in animal models, […]
2018-12-02 09:00:00
2018-12-15 18:00:00
Europe/Paris
10th HKU-Pasteur Immunology Course: December 2-15, 2018
‘Quantitative Immunology’ will be the theme of the 10th anniversary of the HKU-Pasteur Immunology Course. We will explore the ongoing transition from reductionist studies, based on the application of genetic approaches in animal models, […]
HKU-Pasteur Research Centre, Hong Kong
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2024The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies., Immunity 2024 Jul; 57(7): 1696-1709.e10.
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2024Impact of socioeconomic status on healthy immune responses in humans., Immunol Cell Biol 2024 Jun; (): .
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2024MANOCCA: a robust and computationally efficient test of covariance in high-dimension multivariate omics data., Brief Bioinform 2024 May; 25(4): .
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2024Increased levels of GM-CSF and CXCL10 and low CD8+ memory stem T Cell count are markers of immunosenescence and severe COVID-19 in older people., Immun Ageing 2024 May; 21(1): 28.
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2024Sarcoidosis immunopathogenesis – a new concept of maladaptive trained immunity, Trends Immunol. 2024 May 24:S1471-4906(24)00101-7.
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2024Systems vaccinology studies – achievements and future potential., Microbes Infect 2024 Mar; (): 105318.
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2024Smoking changes adaptive immunity with persistent effects., Nature 2024 Feb; 626(8000): 827-835.
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2024Standardized high-dimensional spectral cytometry protocol and panels for whole blood immune phenotyping in clinical and translational studies., Cytometry A 2024 Feb; 105(2): 124-138.
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2024VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation., Nat Commun 2024 Jan; 15(1): 910.
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2024Deciphering the relationship between temperature and immunity., Discov Immunol 2024 ; 3(1): kyae001.
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