Single cell gene expression and beyond
Course Overview The course aims at providing theoretical and hands-on training for all steps of high-throughput single cell profiling, from single-cell sample and library preparation to data analysis, using state-of-the-art technological solutions. Program This […]
Single Cell Resources Initiative at Institut Pasteur
Introduction. Cell-to-cell variation affects all biological systems and processes, from stem cells and development, to immunology or cancer. Conventional population (bulk) measurements provide averaged information that does not reveal cellular individuality and masks extreme […]
Single cell projects
Numerous research groups from the Institut Pasteur, from the Pasteur International Network (RIIP) and from various external academic and clinical institutions benefit from the single cell resources of the Institut Pasteur. The groups with […]
Single Cell Transcriptomics
The single cell transcriptomics, epigenetic and genomics are supported by collaborative effort of the CB UTechS and Biomics. The CB UTechS gathers expertise and high-end instrumentation for single cell phenotyping and sorting, single cell […]
2022Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry., Nat Commun 2022 Jan; 13(1): 521.
2021Single-Cell and Bulk RNA-Sequencing Reveal Differences in Monocyte Susceptibility to Influenza A Virus Infection Between Africans and Europeans., Front Immunol 2021 ; 12(): 768189.
2018Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors., Nat Immunol 2018 03; 19(3): 302-314.
2016Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses, DOI: http://dx.doi.org/10.1016/j.celrep.2016.08.011 show.
2016Protein biomarkers discriminate Leishmania major-infected and non-infected individuals in areas endemic for cutaneous leishmaniasis, BMC Infect. Dis. 2016;16:138.
2015Automated flow cytometric analysis across large numbers of samples and cell types, Clin. Immunol. 2015 Apr;157(2):249-60.
2014Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli, Immunity 2014 Mar;40(3):436-50.