Timeline

Rachel Legendre
Research Engineer
09 Mar 2024
publication

Comparative analysis of rabies pathogenic and vaccine strains detection by RIG-I-like receptors.

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01 Mar 2024
publication

Prosaposin maintains adult neural stem cells in a state associated with deep quiescence

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15 Feb 2024
course

12ème Ecole de bioinformatique AVIESAN – IFB – Inserm Niveau1 (2023)

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30 Nov 2023
publication

Transcriptome profiling of human col\onic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus.

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06 Oct 2023
news

New publication – Depletion of slow-cycling PDGFRα+ADAM12+ mesenchymal cells promotes antitumor immunity by restricting macrophage efferocytosis.

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05 Oct 2023
publication

Depletion of slow-cycling PDGFRα+ADAM12+ mesenchymal cells promotes antitumor immunity by restricting macrophage efferocytosis.

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29 Nov 2022
course

2ème Ecole de Bioinformatique AVIESAN – IFB – INSERM Niveau 2

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29 Nov 2022
course

11ème école de bioinformatique AVIESAN-INSERM-IFB

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27 Aug 2022
publication

IRF8 regulates efficacy of therapeutic anti-CD20 monoclonal antibodies.

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15 Jul 2022
publication

Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1

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10 Jun 2022
software

ePeak

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01 Jun 2022
publication

ePeak: from replicated chromatin profiling data to epigenomic dynamics.

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06 May 2022
news

New publication – PDGFRα-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms

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05 May 2022
publication

PDGFRα-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms.

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15 Apr 2022
news

A recent study by the team of Laurent Debarbieux has been highlighted in the BIP (15/04/2022)

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13 Apr 2022
publication

The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection.

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01 Mar 2022
publication

Mosquito-bacteria interactions during larval development trigger metabolic changes with carry-over effects on adult fitness.

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01 Mar 2022
publication

Experimental evolution links post-transcriptional regulation to Leishmania fitness gain.

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25 Feb 2022
publication

Trained ILC3 responses promote intestinal defense.

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03 Feb 2022
course

Multiple roles of RNAs

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31 Jan 2022
course

1ere école EBAII Assemblage & Annotation

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22 Dec 2021
publication

sgDI-tector: defective interfering viral genome bioinformatics for detection of coronavirus subgenomic RNAs

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14 Dec 2021
project

Towards understanding of immunostimulatory properties of SARS-CoV-2 RNAs

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13 Dec 2021
publication

Early Transcriptional Changes in Rabies Virus-Infected Neurons and Their Impact on Neuronal Functions.

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01 Dec 2021
publication

The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence.

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17 Oct 2021
publication

Role of the major determinant of polar flagellation FlhG in the endoflagella-containing spirochete Leptospira.

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01 Sep 2021
publication

The CovR regulatory network drives the evolution of Group B Streptococcus virulence.

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27 Jul 2021
publication

HP1γ binding pre-mRNA intronic repeats modulates RNA splicing decisions.

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10 Jun 2021
publication

Transcriptional adaptation of Mycobacterium ulcerans in an original mouse model: New insights into the regulation of mycolacton

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18 May 2021
publication

Functional Genomic and Biochemical Analysis Reveals Pleiotropic Effect of Congo Red on Aspergillus fumigatus.

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16 Apr 2021
course

1ème Ecole de Bioinformatique AVIESAN – IFB – INSERM Niveau 2

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09 Mar 2021
publication

Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator.

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24 Feb 2021
publication

SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity.

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18 Feb 2021
publication

Tissue damage induces a conserved stress response that initiates quiescent muscle stem cell activation.

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12 Jan 2021
project

Insights into amebiasis using a human 3D-intestinal model (ANR-14-IFEC-0001-02)

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06 Jan 2021
publication

Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring.

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04 Jan 2021
publication

Systemic viral spreading and defective host responses are associated with fatal Lassa fever in macaques.

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01 Jan 2021
publication

CD32+CD4+ T Cells Sharing B Cell Properties Increase With Simian Immunodeficiency Virus Replication in Lymphoid Tissues.

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02 Dec 2020
publication

4-Methylcytosine DNA modification is critical for global epigenetic regulation and virulence in the human pathogen Leptospira interrogans.

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01 Nov 2020
publication

Functionally distinct resident macrophage subsets differentially shape responses to infection in the bladder.

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06 Oct 2020
publication

The transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress.

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24 Sep 2020
course

Bioinformatics program for PhD students 2020-2021

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01 Aug 2020
publication

Insights into amebiasis using a human 3D-intestinal model.

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02 Jun 2020
publication

Human Immune Response Triggered by Entamoeba histolytica in a 3D-Intestinal Model

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14 May 2020
publication

BAHD1 haploinsufficiency results in anxiety-like phenotypes in male mice

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04 May 2020
publication

Intracellular Staphylococcus aureus persisters upon antibiotic exposure

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13 Apr 2020
publication

Transcytosis subversion by M cell-to-enterocyte spread promotes Shigella flexneri and Listeria monocytogenes  intracellular bacterial dissemination

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08 Nov 2019
publication

Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

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21 Oct 2019
publication

Non-specific interference of cobalt with siderophore-dependent iron uptake pathways

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02 Aug 2019
team

Biomics – Dry-Lab

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15 May 2019
publication

Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid

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19 Jul 2018
project

Bioconvert

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06 Jul 2018
publication

Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries

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13 Jun 2018
publication

Enteric bacteria boost defences against oxidative stress in Entamoeba histolytica

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16 May 2018
course

7ème école de bioinformatique AVIESAN-IFB

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28 Mar 2018
team

Expertise group: GORE – Genome Organization Regulation and Expression

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19 Jan 2018
publication

Sequanix: A Dynamic Graphical Interface for Snakemake Workflows

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16 Nov 2017
publication

A missense variant in the coil1A domain of the keratin 25 gene is associated with the dominant curly hair coat trait (Crd) in horse

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14 Nov 2017
publication

In Situ Fixation Redefines Quiescence and Early Activation of Skeletal Muscle Stem Cells

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31 Oct 2017
course

Hands-on course on High Throughput Sequencing data analysis: Genomics, Transcriptomics, Epigenomics

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19 Apr 2017
course

6ème école de bioinformatique AVIESAN-IFB

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02 Feb 2017
project

Deciphering the virulence factors of Mycobacterium abscessus activated in the presence of environmental amoebae

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31 Jan 2017
project

Transcriptome of different quiescence sub-states of neural stem cells in adult zebrafish

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31 Jan 2017
project

The role of lncRNA H19 in Thymopoiesis

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24 Jan 2017
event

Journée ChIP-seq WP2.6 France Génomique

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29 Nov 2016
course

5ème école de bioinformatique AVIESAN-IFB

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22 Nov 2016
software

Sequana: a set of flexible NGS pipelines

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12 Oct 2016
event

5th school of bioinformatics AVIESAN-IFB

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22 Sep 2016
course

Workshop: Bacterial RNAseq

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15 Jun 2016
publication

GH16 and GH81 family β-(1,3)-glucanases in Aspergillus fumigatus are essential for conidial cell wall morphogenesis

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18 May 2016
project

Gene expression profiling in germinal center B cells

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26 Apr 2016
event

Training: analysis of the transcriptome by RNAseq

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20 Apr 2016
course

Training: analysis of the transcriptome by RNAseq

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02 Jan 2016
publication

Translation Analysis at the Genome Scale by Ribosome Profiling

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01 Jan 2016
publication

Global translational impacts of the loss of the tRNA modification t6A in yeast

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14 Sep 2015
project

HIV signature on RIG-I-like receptors

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08 Sep 2015
project

Dynamic regulation of chromatin and transcription by HP1 Heterochromatin Proteins in relationship with RNA.

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07 Sep 2015
publication

VING: a software for visualization of deep sequencing signals

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26 Jun 2015
team

Bioinformatics and Biostatistics HUB

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18 Mar 2015
team

Biomics

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15 Mar 2015
publication

RiboTools: a Galaxy toolbox for qualitative ribosome profiling analysis

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31 Jan 2015
project

Régulation transcriptionnelle par l’Enhancer de Trithorax et Polycomb Corto et la Protéine Ribosomique L12.

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17 Sep 2014
publication

Next-generation sequencing identifies equine cartilage and subchondral bone miRNAs and suggests their involvement in osteochondrosis physiopathology

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24 Jul 2014
publication

Genome-wide translational changes induced by the prion [PSI+]

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20 Mar 2014
publication

Involvement of mitochondrial dysfunction and ER-stress in the physiopathology of equine osteochondritis dissecans (OCD)

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05 Oct 2012
publication

Hyperstructure interactions influence the virulence of the type 3 secretion system in yersiniae and other bacteria

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19 Mar 2012
publication

Evolution of class A G-protein-coupled receptors: implications for molecular modeling

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