Timeline

Catherine Werts
Group Leader
04 Dec 2018
project

PTR66-2017 Role of Toll-Like and Nod-Like Receptors in the activation and functions of phagocytes infected with pathogenic Leptospira

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13 Feb 2018
publication

Recent findings related to immune responses against leptospirosis and novel strategies to prevent infection

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19 Jan 2018
publication

Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages

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01 Jan 2018
publication

Interaction of Leptospira with the Innate Immune System

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06 Dec 2017
publication

LipL21 lipoprotein binding to peptidoglycan enables Leptospira interrogans to escape NOD1 and NOD2 recognition

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25 Aug 2017
publication

Pre-treatment with Lactobacillus plantarum prevents severe pathogenesis in mice infected with Leptospira interrogans and may be associated with recruitment of myeloid cells

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21 Feb 2017
publication

Animal Models of Leptospirosis: Of Mice and Hamsters

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08 Apr 2016
event

Journées du Département de Microbiologie

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14 Sep 2015
project

ERC-2007-Stg-202283-PGNfromSHAPEtoVIR

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16 Jul 2015
team

Group: Innate Immunity and Leptospira

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10 Jul 2015
publication

Common Cell Shape Evolution of Two Nasopharyngeal Pathogens

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02 Jul 2015
project

Biology and Genetics of Bacterial Cell Wall

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11 May 2015
team

Biology and Genetics of Bacterial Cell Wall

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02 Apr 2015
publication

CCL20 Displays Antimicrobial Activity Against Cryptosporidium parvum, but Its Expression Is Reduced During Infection in the Intestine of Neonatal Mice

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04 Dec 2014
publication

Live imaging of bioluminescent leptospira interrogans in mice reveals renal colonization as a stealth escape from the blood defenses and antibiotics

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23 May 2014
publication

Flagellin/TLR5 signalling activates renal collecting duct cells and facilitates invasion and cellular translocation of uropathogenic Escherichia coli

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30 Jan 2014
publication

Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways

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30 Jan 2014
publication

Calcineurin/NFAT signaling and innate host defence: a role for NOD1-mediated phagocytic functions

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06 Sep 2013
publication

Poly(I:C)-induced protection of neonatal mice against intestinal Cryptosporidium parvum infection requires an additional TLR5 signal provided by the gut flora

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17 Jun 2013
publication

LIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis

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12 Jun 2013
publication

Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis

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31 Jan 2013
publication

Cyclosporine A impairs nucleotide binding oligomerization domain (Nod1)-mediated innate antibacterial renal defenses in mice and human transplant recipients

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20 Mar 2012
publication

The effect of bulgecin A on peptidoglycan metabolism and physiology of Helicobacter pylori

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08 Feb 2012
publication

Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome

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07 Jun 2011
publication

Nod-like receptors in intestinal homeostasis, inflammation, and cancer

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01 Nov 2010
publication

Leptospirosis: a Toll road from B lymphocytes

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19 May 2010
publication

TLR9-dependent induction of intestinal alpha-defensins by Toxoplasma gondii

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12 Mar 2010
publication

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury

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27 Jul 2009
publication

TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans

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05 Mar 2009
publication

Heat shock protein gp96 interacts with protein phosphatase 5 and controls toll-like receptor 2 (TLR2)-mediated activation of extracellular signal-regulated kinase (ERK) 1/2 in post-hypoxic kidney cells

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01 Mar 2008
publication

The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals

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01 Feb 2008
publication

[Molecular cross talk between Toxoplasma gondii and the host immune system]

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01 Sep 2007
publication

Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway

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27 Jan 2007
publication

Role of Nods in bacterial infection

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19 Jan 2007
publication

Simple method for repurification of endotoxins for biological use

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01 Oct 2006
publication

Renal collecting duct epithelial cells react to pyelonephritis-associated Escherichia coli by activating distinct TLR4-dependent and -independent inflammatory pathways

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01 Sep 2006
publication

Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape

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01 May 2006
publication

TIR, CARD and PYRIN: three domains for an antimicrobial triad

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01 Nov 2005
publication

Differential TLR recognition of leptospiral lipid A and lipopolysaccharide in murine and human cells

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22 Aug 2005
publication

The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists

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01 Aug 2005
publication

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists

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10 Sep 2004
publication

Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition

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24 Mar 2004
publication

A methylated phosphate group and four amide-linked acyl chains in leptospira interrogans lipid A. The membrane anchor of an unusual lipopolysaccharide that activates TLR2

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24 Mar 2004
publication

Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3″-hydroxyl group

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22 Oct 2003
publication

Helicobacter pylori heat shock protein 60 mediates interleukin-6 production by macrophages via a toll-like receptor (TLR)-2-, TLR-4-, and myeloid differentiation factor 88-independent mechanism

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08 May 2003
publication

Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation

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20 Feb 2003
publication

Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway

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01 Aug 2002
publication

TNF-alpha, inefficient by itself, potentiates IL-1beta-induced PGHS-2 expression in human pulmonary microvascular endothelial cells: requirement of NF-kappaB and p38 MAPK pathways

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24 Jul 2001
publication

First evidence for a restriction-modification system in Leptospira sp

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01 Apr 2001
publication

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism

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01 Jun 1994
publication

A role for residue 151 of LamB in bacteriophage lambda adsorption: possible steric effect of amino acid substitutions

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01 Feb 1994
publication

Adsorption of bacteriophage lambda on the LamB protein of Escherichia coli K-12: point mutations in gene J of lambda responsible for extended host range

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01 May 1993
publication

Construction and first characterization of two reciprocal hybrids between LamB from Escherichia coli K12 and Klebsiella pneumoniae

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01 Apr 1993
publication

Immunological relatedness of the LamB proteins among members of Enterobacteriaceae

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01 Jun 1992
publication

DNA sequence analysis of the lamB gene from Klebsiella pneumoniae: implications for the topology and the pore functions in maltoporin

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01 Feb 1991
publication

A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis

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01 Jan 1991
publication

Permissive sites and topology of an outer membrane protein with a reporter epitope

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