Ligne de temps

Catherine Werts
Chef(fe) de Groupe
06 févr. 2024
project

Étude de la réponse immunitaire innée au cours de la Leptopirose : LEPTBLOOD (2023-029)

Lire plus
09 déc. 2023
publication

Leptospiral lipopolysaccharide dampens inflammation through upregulation of autophagy adaptor p62 and NRF2 signaling in macrophages.

Lire plus
04 janv. 2023
publication

Leptospira interrogans Prevents Macrophage Cell Death and Pyroptotic IL-1β Release through Its Atypical Lipopolysaccharide.

Lire plus
20 janv. 2022
team

Interactions hôte-microbes et pathophysiologie

Lire plus
01 janv. 2022
publication

Pathogenic Leptospires Limit Dendritic Cell Activation Through Avoidance of TLR4 and TRIF Signaling.

Lire plus
01 janv. 2022
publication

Alive Pathogenic and Saprophytic Leptospires Enter and Exit Human and Mouse Macrophages With No Intracellular Replication.

Lire plus
07 sept. 2021
publication

Recent findings related to immune responses against leptospirosis and novel strategies to prevent infection.

Lire plus
07 sept. 2021
publication

Interaction of Leptospira with the Innate Immune System.

Lire plus
07 sept. 2021
publication

Leptospirosis: a Toll road from B lymphocytes.

Lire plus
01 mars 2021
publication

Anti-Leptospira immunoglobulin profiling in mice reveals strain specific IgG and persistent IgM responses associated with virulence and renal colonization.

Lire plus
01 août 2020
publication

Leptospiral LPS escapes mouse TLR4 internalization and TRIF‑associated antimicrobial responses through O antigen and associated lipoproteins.

Lire plus
01 janv. 2020
publication

Role of TLR4 in Persistent Leptospira interrogans Infection: A Comparative In Vivo Study in Mice.

Lire plus
01 janv. 2020
publication

Phagocyte Escape of Leptospira: The Role of TLRs and NLRs.

Lire plus
01 janv. 2020
publication

In Vivo Imaging of Bioluminescent Leptospires.

Lire plus
01 janv. 2020
publication

The route of infection with Leptospira interrogans serovar Copenhageni affects the kinetics of bacterial dissemination and kidney colonization.

Lire plus
01 janv. 2020
publication

Escape of TLR5 Recognition by Leptospira spp.: A Rationale for Atypical Endoflagella.

Lire plus
01 janv. 2020
publication

Purification of LPS from Leptospira.

Lire plus
01 mai 2019
publication

Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection.

Lire plus
04 déc. 2018
project

PTR66-2017 Role of Toll-Like and Nod-Like Receptors in the activation and functions of phagocytes infected with pathogenic Leptospira

Lire plus
01 janv. 2018
publication

Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages.

Lire plus
01 déc. 2017
publication

LipL21 lipoprotein binding to peptidoglycan enables Leptospira interrogans to escape NOD1 and NOD2 recognition.

Lire plus
01 août 2017
publication

Pre-treatment with Lactobacillus plantarum prevents severe pathogenesis in mice infected with Leptospira interrogans and may be associated with recruitment of myeloid cells.

Lire plus
15 mai 2017
publication

LIM-Only Protein FHL2 Is a Negative Regulator of Transforming Growth Factor β1 Expression.

Lire plus
01 janv. 2017
publication

Animal Models of Leptospirosis: Of Mice and Hamsters.

Lire plus
08 avr. 2016
event

Journées du Département de Microbiologie

Lire plus
15 oct. 2015
publication

CCL20 Displays Antimicrobial Activity Against Cryptosporidium parvum, but Its Expression Is Reduced During Infection in the Intestine of Neonatal Mice.

Lire plus
14 sept. 2015
project

ERC-2007-Stg-202283-PGNfromSHAPEtoVIR

Lire plus
16 juil. 2015
team

Groupe: Innate immunity and Leptospira

Lire plus
02 juil. 2015
project

Biology and Genetics of Bacterial Cell Wall

Lire plus
01 juil. 2015
publication

Common Cell Shape Evolution of Two Nasopharyngeal Pathogens.

Lire plus
11 mai 2015
team

Biologie et Génétique de la Paroi Bactérienne

Lire plus
01 déc. 2014
publication

Live imaging of bioluminescent leptospira interrogans in mice reveals renal colonization as a stealth escape from the blood defenses and antibiotics.

Lire plus
23 mai 2014
publication

Flagellin/TLR5 signalling activates renal collecting duct cells and facilitates invasion and cellular translocation of uropathogenic Escherichia coli

Lire plus
30 janv. 2014
publication

Calcineurin/NFAT signaling and innate host defence: a role for NOD1-mediated phagocytic functions

Lire plus
01 janv. 2014
publication

Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways.

Lire plus
06 sept. 2013
publication

Poly(I:C)-induced protection of neonatal mice against intestinal Cryptosporidium parvum infection requires an additional TLR5 signal provided by the gut flora

Lire plus
01 août 2013
publication

LIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis.

Lire plus
12 juin 2013
publication

Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis.

Lire plus
31 janv. 2013
publication

Cyclosporine A impairs nucleotide binding oligomerization domain (Nod1)-mediated innate antibacterial renal defenses in mice and human transplant recipients

Lire plus
01 janv. 2013
publication

Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice.

Lire plus
01 juin 2012
publication

The effect of bulgecin A on peptidoglycan metabolism and physiology of Helicobacter pylori.

Lire plus
15 mars 2012
publication

Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome.

Lire plus
01 sept. 2011
publication

Nod-like receptors in intestinal homeostasis, inflammation, and cancer.

Lire plus
19 mai 2010
publication

TLR9-dependent induction of intestinal alpha-defensins by Toxoplasma gondii

Lire plus
12 mars 2010
publication

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury

Lire plus
27 juil. 2009
publication

TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans

Lire plus
05 mars 2009
publication

Heat shock protein gp96 interacts with protein phosphatase 5 and controls toll-like receptor 2 (TLR2)-mediated activation of extracellular signal-regulated kinase (ERK) 1/2 in post-hypoxic kidney cells

Lire plus
27 nov. 2008
publication

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis.

Lire plus
01 mars 2008
publication

The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals

Lire plus
01 févr. 2008
publication

[Molecular cross talk between Toxoplasma gondii and the host immune system].

Lire plus
01 sept. 2007
publication

Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway.

Lire plus
01 avr. 2007
publication

Role of Nods in bacterial infection.

Lire plus
19 janv. 2007
publication

Simple method for repurification of endotoxins for biological use

Lire plus
01 oct. 2006
publication

Toxoplasma gondii and subversion of the immune system.

Lire plus
01 oct. 2006
publication

Renal collecting duct epithelial cells react to pyelonephritis-associated Escherichia coli by activating distinct TLR4-dependent and -independent inflammatory pathways

Lire plus
01 sept. 2006
publication

Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape.

Lire plus
01 mai 2006
publication

TIR, CARD and PYRIN: three domains for an antimicrobial triad

Lire plus
01 nov. 2005
publication

Differential TLR recognition of leptospiral lipid A and lipopolysaccharide in murine and human cells.

Lire plus
22 août 2005
publication

The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists

Lire plus
01 août 2005
publication

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.

Lire plus
01 oct. 2004
publication

Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition.

Lire plus
24 mars 2004
publication

A methylated phosphate group and four amide-linked acyl chains in leptospira interrogans lipid A. The membrane anchor of an unusual lipopolysaccharide that activates TLR2

Lire plus
24 mars 2004
publication

Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3″-hydroxyl group

Lire plus
02 janv. 2004
publication

Helicobacter pylori heat shock protein 60 mediates interleukin-6 production by macrophages via a toll-like receptor (TLR)-2-, TLR-4-, and myeloid differentiation factor 88-independent mechanism.

Lire plus
15 juil. 2003
publication

Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation.

Lire plus
20 févr. 2003
publication

Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway.

Lire plus
01 août 2002
publication

TNF-alpha, inefficient by itself, potentiates IL-1beta-induced PGHS-2 expression in human pulmonary microvascular endothelial cells: requirement of NF-kappaB and p38 MAPK pathways.

Lire plus
24 juil. 2001
publication

First evidence for a restriction-modification system in Leptospira sp

Lire plus
01 avr. 2001
publication

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism

Lire plus
01 juin 1994
publication

A role for residue 151 of LamB in bacteriophage lambda adsorption: possible steric effect of amino acid substitutions

Lire plus
01 févr. 1994
publication

Adsorption of bacteriophage lambda on the LamB protein of Escherichia coli K-12: point mutations in gene J of lambda responsible for extended host range

Lire plus
01 mai 1993
publication

Construction and first characterization of two reciprocal hybrids between LamB from Escherichia coli K12 and Klebsiella pneumoniae

Lire plus
01 avr. 1993
publication

Immunological relatedness of the LamB proteins among members of Enterobacteriaceae

Lire plus
01 juin 1992
publication

DNA sequence analysis of the lamB gene from Klebsiella pneumoniae: implications for the topology and the pore functions in maltoporin

Lire plus
01 févr. 1991
publication

A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis

Lire plus
01 janv. 1991
publication

Permissive sites and topology of an outer membrane protein with a reporter epitope

Lire plus