Ligne de temps
Catherine Werts
Chef(fe) de Groupe
06 févr. 2024
project
Étude de la réponse immunitaire innée au cours de la Leptopirose : LEPTBLOOD (2023-029)
Lire plus09 déc. 2023
publication
Leptospiral lipopolysaccharide dampens inflammation through upregulation of autophagy adaptor p62 and NRF2 signaling in macrophages.
Lire plus04 janv. 2023
publication
Leptospira interrogans Prevents Macrophage Cell Death and Pyroptotic IL-1β Release through Its Atypical Lipopolysaccharide.
Lire plus20 janv. 2022
01 janv. 2022
publication
Pathogenic Leptospires Limit Dendritic Cell Activation Through Avoidance of TLR4 and TRIF Signaling.
Lire plus01 janv. 2022
publication
Alive Pathogenic and Saprophytic Leptospires Enter and Exit Human and Mouse Macrophages With No Intracellular Replication.
Lire plus07 sept. 2021
publication
Recent findings related to immune responses against leptospirosis and novel strategies to prevent infection.
Lire plus07 sept. 2021
07 sept. 2021
01 mars 2021
publication
Anti-Leptospira immunoglobulin profiling in mice reveals strain specific IgG and persistent IgM responses associated with virulence and renal colonization.
Lire plus01 août 2020
publication
Leptospiral LPS escapes mouse TLR4 internalization and TRIF‑associated antimicrobial responses through O antigen and associated lipoproteins.
Lire plus01 janv. 2020
publication
Role of TLR4 in Persistent Leptospira interrogans Infection: A Comparative In Vivo Study in Mice.
Lire plus01 janv. 2020
01 janv. 2020
01 janv. 2020
publication
The route of infection with Leptospira interrogans serovar Copenhageni affects the kinetics of bacterial dissemination and kidney colonization.
Lire plus01 janv. 2020
publication
Escape of TLR5 Recognition by Leptospira spp.: A Rationale for Atypical Endoflagella.
Lire plus01 janv. 2020
01 mai 2019
publication
Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection.
Lire plus04 déc. 2018
project
PTR66-2017 Role of Toll-Like and Nod-Like Receptors in the activation and functions of phagocytes infected with pathogenic Leptospira
Lire plus01 janv. 2018
publication
Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages.
Lire plus01 déc. 2017
publication
LipL21 lipoprotein binding to peptidoglycan enables Leptospira interrogans to escape NOD1 and NOD2 recognition.
Lire plus01 août 2017
publication
Pre-treatment with Lactobacillus plantarum prevents severe pathogenesis in mice infected with Leptospira interrogans and may be associated with recruitment of myeloid cells.
Lire plus15 mai 2017
publication
LIM-Only Protein FHL2 Is a Negative Regulator of Transforming Growth Factor β1 Expression.
Lire plus01 janv. 2017
08 avr. 2016
15 oct. 2015
publication
CCL20 Displays Antimicrobial Activity Against Cryptosporidium parvum, but Its Expression Is Reduced During Infection in the Intestine of Neonatal Mice.
Lire plus14 sept. 2015
16 juil. 2015
02 juil. 2015
01 juil. 2015
11 mai 2015
01 déc. 2014
publication
Live imaging of bioluminescent leptospira interrogans in mice reveals renal colonization as a stealth escape from the blood defenses and antibiotics.
Lire plus23 mai 2014
publication
Flagellin/TLR5 signalling activates renal collecting duct cells and facilitates invasion and cellular translocation of uropathogenic Escherichia coli
Lire plus30 janv. 2014
publication
Calcineurin/NFAT signaling and innate host defence: a role for NOD1-mediated phagocytic functions
Lire plus01 janv. 2014
publication
Leptospira Interrogans induces fibrosis in the mouse kidney through Inos-dependent, TLR- and NLR-independent signaling pathways.
Lire plus06 sept. 2013
publication
Poly(I:C)-induced protection of neonatal mice against intestinal Cryptosporidium parvum infection requires an additional TLR5 signal provided by the gut flora
Lire plus01 août 2013
publication
LIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis.
Lire plus12 juin 2013
publication
Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis.
Lire plus31 janv. 2013
publication
Cyclosporine A impairs nucleotide binding oligomerization domain (Nod1)-mediated innate antibacterial renal defenses in mice and human transplant recipients
Lire plus01 janv. 2013
publication
Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice.
Lire plus01 juin 2012
publication
The effect of bulgecin A on peptidoglycan metabolism and physiology of Helicobacter pylori.
Lire plus15 mars 2012
publication
Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome.
Lire plus01 sept. 2011
19 mai 2010
12 mars 2010
publication
Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury
Lire plus27 juil. 2009
publication
TLR4- and TLR2-mediated B cell responses control the clearance of the bacterial pathogen, Leptospira interrogans
Lire plus05 mars 2009
publication
Heat shock protein gp96 interacts with protein phosphatase 5 and controls toll-like receptor 2 (TLR2)-mediated activation of extracellular signal-regulated kinase (ERK) 1/2 in post-hypoxic kidney cells
Lire plus27 nov. 2008
publication
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis.
Lire plus01 mars 2008
publication
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals
Lire plus01 févr. 2008
01 sept. 2007
01 avr. 2007
19 janv. 2007
01 oct. 2006
01 oct. 2006
publication
Renal collecting duct epithelial cells react to pyelonephritis-associated Escherichia coli by activating distinct TLR4-dependent and -independent inflammatory pathways
Lire plus01 sept. 2006
publication
Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape.
Lire plus01 mai 2006
01 nov. 2005
publication
Differential TLR recognition of leptospiral lipid A and lipopolysaccharide in murine and human cells.
Lire plus22 août 2005
publication
The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists
Lire plus01 août 2005
publication
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
Lire plus01 oct. 2004
publication
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition.
Lire plus24 mars 2004
publication
A methylated phosphate group and four amide-linked acyl chains in leptospira interrogans lipid A. The membrane anchor of an unusual lipopolysaccharide that activates TLR2
Lire plus24 mars 2004
publication
Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3″-hydroxyl group
Lire plus02 janv. 2004
publication
Helicobacter pylori heat shock protein 60 mediates interleukin-6 production by macrophages via a toll-like receptor (TLR)-2-, TLR-4-, and myeloid differentiation factor 88-independent mechanism.
Lire plus15 juil. 2003
publication
Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation.
Lire plus20 févr. 2003
publication
Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway.
Lire plus01 août 2002
publication
TNF-alpha, inefficient by itself, potentiates IL-1beta-induced PGHS-2 expression in human pulmonary microvascular endothelial cells: requirement of NF-kappaB and p38 MAPK pathways.
Lire plus24 juil. 2001
01 avr. 2001
publication
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism
Lire plus01 juin 1994
publication
A role for residue 151 of LamB in bacteriophage lambda adsorption: possible steric effect of amino acid substitutions
Lire plus01 févr. 1994
publication
Adsorption of bacteriophage lambda on the LamB protein of Escherichia coli K-12: point mutations in gene J of lambda responsible for extended host range
Lire plus01 mai 1993
publication
Construction and first characterization of two reciprocal hybrids between LamB from Escherichia coli K12 and Klebsiella pneumoniae
Lire plus01 avr. 1993
publication
Immunological relatedness of the LamB proteins among members of Enterobacteriaceae
Lire plus01 juin 1992
publication
DNA sequence analysis of the lamB gene from Klebsiella pneumoniae: implications for the topology and the pore functions in maltoporin
Lire plus01 févr. 1991
publication
A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis
Lire plus01 janv. 1991
publication