Timeline

Nathalie Aulner

Head of Facility

31 Jul 2023

event

Inauguration new BSL2 imaging lab

24 Feb 2023

event

Symposium and Workshop “Pushing the frontiers of dynamic imaging”

23 Jun 2022

event

Open Microscopy Symposium

09 May 2022

event

Combination of spectroscopy with microscopy enables new dimensions in quantitative biology – Leonel Malacrida, IP Montevideo

07 Dec 2021

news

New two-photon microscope open for new projects at Photonic Bio Imaging Facility

07 Dec 2021

news

New Super Resolution microscope open for new projects at Photonic Bio Imaging at PBI

18 Nov 2021

event

CANCELLED – Demonstration Aquifer Imaging Machine

02 Jul 2021

publication

LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images.

17 May 2021

program_project

Advanced Light Microscopy initiative

19 Feb 2021

event

C2RT TECHNOLOGICAL SEMINARS : The ACQUIFER Imaging Machine

01 Jan 2021

publication

Corrigendum: Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

14 Dec 2020

news

Season Greetings 2023/24

25 Jun 2020

publication

A Role for Taok2 in Listeria monocytogenes Vacuolar Escape.

11 Feb 2020

publication

Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response.

01 Jan 2020

publication

Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

12 Nov 2019

tool

Single Cell Phenotyping – Microscopy

01 Oct 2019

news

PBI User satisfaction Survey 2019

10 Sep 2019

news

Pascal

10 Jul 2019

news

SUMMER 2019 @ PBI

09 Jul 2019

publication

Author Correction: Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening.

05 Jun 2019

publication

Next-Generation Phenotypic Screening in Early Drug Discovery for Infectious Diseases

24 Jan 2019

publication

Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening.

13 Jun 2018

news

Demonstration of new Light-Sheet microscope: Alpha3 light sheet microscope

13 Jun 2018

news

Thursday, July 12 : Presentation from Zeiss compagny on “Machine learning, intelligent imaging, multi-scale correlative: the innovations of the ZEN software to gain autonomy”

01 Jun 2018

publication

Fluorescence imaging host pathogen interactions: fifteen years benefit of hindsight….

27 Feb 2018

event

Rémi Galland, University of Bordeaux, Interdisciplinary Institute for Neurosciences

27 Feb 2018

event

Alain Chedotal, Institut de la Vision, Paris

27 Feb 2018

event

Fluorescence Microscopy Workshop III/on cutting-technologies

27 Feb 2018

event

Fluorescence Microscopy Workshop III/on cutting-edge technologies

05 Dec 2017

news

Microscopy Core OpenDesk

17 Aug 2017

team

Photonic BioImaging (UTechS PBI)

01 Jan 2017

publication

Assessing Vacuolar Escape of Listeria Monocytogenes

12 Sep 2016

publication

Screening out irrelevant cell-based models of disease.

01 May 2016

publication

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.

10 Apr 2016

tool

Dual microscopy assay to discriminate Listeria cellular entry & vacuolar escape

23 Oct 2015

publication

A Dual Microscopy-Based Assay To Assess Listeria monocytogenes Cellular Entry and Vacuolar Escape

07 Sep 2015

project

FP7 Targeting the Leishmania kinome for the development of novel anti-parasitic strategies (LeishDrug)

07 Sep 2015

project

PTR 496 – Investigating the reciprocal relationship between macrophage inflammasome activity and intracellular Leishmania infection

08 Oct 2014

publication

Shigella subverts the host recycling compartment to rupture its vacuole

01 Jan 2014

publication

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.

21 Oct 2013

publication

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors

04 Apr 2013

publication

High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery

16 Dec 2009

publication

HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes

12 Oct 2009

publication

Intracellular bacteria encode inhibitory SNARE-like proteins

30 Jan 2009

publication

Potent inhibitors of Huntingtin protein aggregation in a cell-based assay

01 Jan 2009

publication

Cell-based assays to probe the ERK MAP kinase pathway in endothelial cells

25 Dec 2008

publication

Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation

30 Oct 2007

publication

Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation

01 Jan 2006

publication

Cell-based assays using primary endothelial cells to study multiple steps in inflammation

01 Jun 2005

publication

Sequence characteristics of functional siRNAs

01 Mar 2005

publication

Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice

15 Dec 2004

publication

CXCR4-tropic HIV-1 envelope glycoprotein functions as a viral chemokine in unstimulated primary CD4+ T lymphocytes

01 Apr 2004

publication

Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene

16 Dec 2002

publication

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.

15 Jul 2002

publication

Modification of position-effect variegation by competition for binding to Drosophila satellites

01 Feb 2002

publication

The AT-hook protein D1 is essential for Drosophila melanogaster development and is implicated in position-effect variegation

15 May 2000

publication

Induction of early transcription in one-cell mouse embryos by microinjection of the nonhistone chromosomal protein HMG-I

01 Oct 1999

publication

The Drosophila poly(A)-binding protein II is ubiquitous throughout Drosophila development and has the same function in mRNA polyadenylation as its bovine homolog in vitro

A little guide for advanced search:

Inauguration new BSL2 imaging lab

Symposium and Workshop “Pushing the frontiers of dynamic imaging”

Open Microscopy Symposium

Combination of spectroscopy with microscopy enables new dimensions in quantitative biology – Leonel Malacrida, IP Montevideo

New two-photon microscope open for new projects at Photonic Bio Imaging Facility

New Super Resolution microscope open for new projects at Photonic Bio Imaging at PBI

CANCELLED – Demonstration Aquifer Imaging Machine

LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images.

Advanced Light Microscopy initiative

C2RT TECHNOLOGICAL SEMINARS : The ACQUIFER Imaging Machine

Corrigendum: Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

Season Greetings 2023/24

A Role for Taok2 in Listeria monocytogenes Vacuolar Escape.

Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response.

Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

Single Cell Phenotyping – Microscopy

PBI User satisfaction Survey 2019

Pascal

SUMMER 2019 @ PBI

Author Correction: Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening.

Next-Generation Phenotypic Screening in Early Drug Discovery for Infectious Diseases

Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening.

Demonstration of new Light-Sheet microscope: Alpha3 light sheet microscope

Thursday, July 12 : Presentation from Zeiss compagny on “Machine learning, intelligent imaging, multi-scale correlative: the innovations of the ZEN software to gain autonomy”

Fluorescence imaging host pathogen interactions: fifteen years benefit of hindsight….

Rémi Galland, University of Bordeaux, Interdisciplinary Institute for Neurosciences

Alain Chedotal, Institut de la Vision, Paris

Fluorescence Microscopy Workshop III/on cutting-technologies

Fluorescence Microscopy Workshop III/on cutting-edge technologies

Microscopy Core OpenDesk

Photonic BioImaging (UTechS PBI)

Assessing Vacuolar Escape of Listeria Monocytogenes

Screening out irrelevant cell-based models of disease.

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.

Dual microscopy assay to discriminate Listeria cellular entry & vacuolar escape

A Dual Microscopy-Based Assay To Assess Listeria monocytogenes Cellular Entry and Vacuolar Escape

FP7 Targeting the Leishmania kinome for the development of novel anti-parasitic strategies (LeishDrug)

PTR 496 – Investigating the reciprocal relationship between macrophage inflammasome activity and intracellular Leishmania infection

Shigella subverts the host recycling compartment to rupture its vacuole

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors

High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery

HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes

Intracellular bacteria encode inhibitory SNARE-like proteins

Potent inhibitors of Huntingtin protein aggregation in a cell-based assay

Cell-based assays to probe the ERK MAP kinase pathway in endothelial cells

Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation

Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation

Cell-based assays using primary endothelial cells to study multiple steps in inflammation

Sequence characteristics of functional siRNAs

Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice

CXCR4-tropic HIV-1 envelope glycoprotein functions as a viral chemokine in unstimulated primary CD4+ T lymphocytes

Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.

Modification of position-effect variegation by competition for binding to Drosophila satellites

The AT-hook protein D1 is essential for Drosophila melanogaster development and is implicated in position-effect variegation

Induction of early transcription in one-cell mouse embryos by microinjection of the nonhistone chromosomal protein HMG-I

The Drosophila poly(A)-binding protein II is ubiquitous throughout Drosophila development and has the same function in mRNA polyadenylation as its bovine homolog in vitro