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© Research
Publication : Infection and immunity

Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice

Team: Archived: Experimental neuropathology
Team: Photonic BioImaging (UTechS PBI)
Member:
Member: Nathalie Aulner
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Infection and immunity - 01 Mar 2005

González-Zorn B, Senna JP, Fiette L, Shorte S, Testard A, Chignard M, Courvalin P, Grillot-Courvalin C

Link to Pubmed [PMID] – 15731086

Infect. Immun. 2005 Mar;73(3):1847-51

Nasal carriage is a major risk factor for Staphylococcus aureus infection, especially for methicillin-resistant strains (MRSA). Using a mouse model of nasal carriage, we have compared several S. aureus strains and demonstrated increased colonization levels by MRSA in cystic fibrosis transmembrane conductance regulator-deficient mice and Toll-like receptor 2 (TLR2)-deficient mice but not TLR4-deficient mice.