Environment and Infectious Risks

EVA-GLOBAL objective is to generate the largest accessible collection of human, animal and plant viruses in the world and move beyond the current state-of-the-art to provide an increasingly valuable resource and service to the […]

This project intends to share expertise, developments, equipement and bioinformatics tools to apply Oxford Nanopore Technology sequencing to the detection, diagnostic and characterization of pathogens of public health importance. It corresponds to a collaboration […]

This project (part of Divide and ConqueR/INTERCEPT project coordinated by Marco Vignuzzi) pertains to the study, construction and use of defective viral genomes in order to combat viral infections. Neurotropic Flaviviruses, for which no […]

This project examines the impact of dynein inhibition on Japanese encephalitis virus (JEV) infectious cycle. Several Flaviviruses (JEV, West Nile virus, yellow fever virus, Zika virus) show alteration of their infectious cycle in the […]

Le projet EBO-SURSY est financé par l’Union Européenne (UE) à hauteur de 8 millions d’euros. Il a été lancé le 15 janvier 2017 dans 10 pays prioritaires pour une période de 5 ans.   […]

Flaviviruses such as Japanese encephalitis virus (JEV), West Nile virus (WNV), Yellow Fever virus (YFV) and Zika virus, can infect neuronals cells and cause neuronal damages, when given access to the central nervous system […]

Neurotropic flaviviruses are human pathogens responsible for numerous viral encephalitic diseases. West Nile and Japanese encephalitis flaviviruses infect the adult brain and are also responsible for congenital infections that impact fetal brain development. Zika […]

Arthropod-borne viruses (arboviruses) include numerous human and animal pathogens that are important global health threats. Flaviviruses are arboviruses belonging to the Flaviviridae family. They include neurotropic viruses such as West Nile (WNV), Japanese encephalitis […]

Despite intensive research efforts on arthropod-borne viruses (arboviruses), many aspects related to immunological consequences of arthropod vector-derived salivary factors are unknown, especially those occurring at the injection site. During a blood meal, arboviruses are […]

Pathogen detection and characterization methods in public health infectious disease surveillance rely on the identification of agents that are already known to be associated with a particular clinical syndrome. Metagenomics, as an emerging field […]

Flavivirus pre-membrane (prM) protein is important in assembly of viral particles. Its ectodomain is well conserved among flaviviruses. Previous work has shown that expression of this domain can trigger apoptosis in mammalian cells and […]

Groupe Arbovirus (GA) de l’Unité Environnement et Risques Infectieux a été créé en 2014. Le GA travaille sur les virus transmis par les arthropodes (Arbovirus), avec un intérêt pour les arbovirus émergents ou réémergents […]

Summary of the project More than 60% of infectious diseases in humans are caused by pathogens likewise circulating in domestic animals and wildlife. Most of these pathogens are viruses whose genome is an RNA […]

About PREDEMICS Infectious diseases have always been a threat to the human population, but since the end of World War II, medical progress fostered the hope that pathogens could be controlled if not eradicated […]

Le PIV est le pôle de virologie de la CIBU. Créé depuis 2003, il intervient dans plusieurs domaines : L’investigation de cas cliniques particuliers, à la demande de l’Institut de Veille Sanitaire (InVS), de la […]

Le PIB est le pôle bactériologique de la CIBU de l’Institut Pasteur. Anciennement appelé Centre d’Identification Moléculaire des Bactéries (CIMB), le laboratoire prend le nom de PIB en 2008. La particularité du PIB est […]

The Genotyping of Pathogens Pole, the centre for microbial genomics of the Environment and Infectious Risks Research and Expertise Unit, provides skills with genotyping and genomics technologies for the characterization of sensitive pathogens and/or […]

The use of light from the abyss in life sciences   In the last decades, bioluminescent systems based on the expression of a luciferase and the addition of a luciferin to monitor the emission […]

Preventing vector-borne diseases around the mediterranean and black sea regions by creating a One Health network of laboratories Countries of the Mediterranean and Black Sea regions share common public health issues and threats.  The MediLabSecure […]