Vector-borne diseases (malaria, dengue, chikungunya fever, Rift Valley, Lyme disease …) are a major concern for human health as well as animal health in a world where the environment is gradually changing. They are among the leading causes of morbidity and mortality in humans and animals. Traditional means of controlling these vector-borne diseases are either inaccessible or have become ineffective. It is therefore necessary to develop new methods to block the transmission of vector-borne diseases, approaches that take into account the complex interaction between the vector, the pathogen and the vertebrate host in order to identify new targets to inhibit transmission. In addition, for several years we have been surprised by the emergence or re-emergence of arboviruses (chikungunya, Zika, yellow fever…) for which we have been slow to implement all the measures necessary to understand the disease, its transmission, its prevention and its possible treatment. These last epidemics have shown our vulnerability and the need to implement new strategies to improve the capacity of health systems to anticipate, prevent and respond to these challenges represented by the low-level circulation of arboviruses in the sensitive areas of emergence that represent the tropical zones at the global level. In addition, temperate zones are no longer immune to these emergences due to the modification of the distribution of vectors. It is in this complex context that we develop several projects concerning ticks and tick-borne diseases and the deciphering of the pathophysiology of emerging arboviruses.
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