On the cover: Type IV pili (T4P), long and flexible appendages at the surface of many bacteria, are critical virulence factors. Pili of enterohemorrhagic E. coli (EHEC), an important human pathogen, are polymers of […]
In the Cell, Proteins and Nucleic Acid assemble into larger structures, called macromolecular complexes. These complexes are specialized biological machineries that accomplish fundamental tasks that are at the basis of life. I employ computer modeling […]
My work focuses on the interplay between the organisation of genomes arising by the chromosomal interactions of cellular processes and the recombination processes generating adaptive genetic variation. Genetic elements tend to be organized in […]
I have concentrated my past and current work on three main research topics: (i) the genetic history of human populations with distinct modes of subsistence, (ii) the role of admixture in genetic adaptation, and […]
SCIENTIFIC POSITIONS Head of Auditory Therapies Innovation Laboratory at the Hearing Institute (an Institut Pasteur Center), Paris Professor “Classe Exceptionnelle” at Institut Pasteur, Paris Professor Emeritus at Collège de France, Chair of Genetics […]
Having begun my research career investigating mitochondria in plants and then neurological diseases, I discovered the first mutations of the NLGN3, NLGN4X and SHANK3 genes in autism highlighting the main role of the synapse […]
Hugo Varet is a biostatistician engineer from the Ensai (Ecole Nationale de la Statistique et de l’Analyse de l’Information) and has been recruited in 2013 by the Transcriptome & Epigenome Platform of the Biomics […]
Jean-Yves background lies in experimental physics and biophysics. He completed his PhD in sensory biophysics, workings on the hair cells of the inner hear in the lab of Pascal Martin, Institut Curie, Paris. He […]
Bioproduction and biomaterials. Microfluidic chips and devices. Project Management. Expertise and advice in robotic and automation projects. (Droplets microarray)
Bernd Jagla is a chemist turned bioinformatician currently working on a R/Shiny application for single-cell RNAseq data analysis called SCHNAPPs, as well as unsupervised cytometry data analysis concentrating on the application of self-organizing maps […]
Jean-Christophe Olivo-Marin is the Head of the Bioimage Analysis unit and the director of the institut Carnot Pasteur Microbes et Santé. He chaired the Cell Biology and Infection Department (2010-2014) and was CTO and […]