Listeria monocytogenes invasion of the central nervous system
We study the host and bacterial factors involved in Listeria monocytogenes invasion of the central nervous system. To this end, we combine in vivo, ex vivo and in vitro systems, as well as imaging, […]
Genomic taxonomy of bacterial strains: universal nomenclatures for epidemiology and population biology
High-throughput sequencing has revolutionized our abilities to track and characterize novel bacterial strains as they emerge and disseminate globally. Genome-based epidemiological typing systems provide ultimate resolution for strain discrimination. Genome sequences may also be […]
Bioinformatics of genome sequencing applied to epidemiological surveillance of infectious agents
The Institut Pasteur has voluminous activities of microbial strain characterisation, in the context of epidemiological surveillance, biological resource centres collections management, and research. These activities involve National Reference Centers, WHO-collaborative centers, biological resources centers […]
Human and ruminant neurolisteriosis: a comparative study (Swiss National Science Foundation, Sinergia)
Neurolisteriosis is a common and frequently fatal complication of Listeria monocytogenes infection in human and ruminants. It has a high impact on human and animal health, but only little is known about its pathogenesis. […]
The LISTERIAGEN project aims to identify host genetic factors associated with susceptibility to listeriosis.
MONALISA: A Multicentric Observational National Analysis on Listeriosis and Listeria (PHRC)
MONALISA is a prospective national study on invasive listeriosis. It aims to identify risk and prognostic factors for invasive listeriosis and to dissect the clinical and biological features of each form of infection (septicemia, central nervous […]
2022Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence., Nature volume 603, pages 900–906 (2022).
2022Neonatal Listeriosis Presentation and Outcome: A Prospective Study of 189 Cases., Clin Infect Dis 2022 01; 74(1): 8-16.
2021Ruminant-associated Listeria monocytogenes isolates belong preferentially to dairy-associated hypervirulent clones: a longitudinal study in 19 farms., Environ Microbiol 2021 Dec; (): .
2021Emergence and global spread of Listeria monocytogenes main clinical clonal complex., Sci Adv 2021 Dec; 7(49): eabj9805.
2021Listeria monocytogenes faecal carriage is common and depends on the gut microbiota., Nat Commun 2021 11; 12(1): 6826.
2017Real-Time Whole-Genome Sequencing for Surveillance of Listeria monocytogenes, France, Emerging Infect. Dis. 2017 09;23(9):1462-1470.
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