A population biology study of Listeria ushers in a new era in listeriosis surveillance
Listeria monocytogenes invasion of the placenta
We study the host and bacterial factors involved in Listeria monocytogenes invasion of the placenta. To this end, we combine in vivo, ex vivo and in vitro systems, as well as imaging, cell biology, […]
Human and ruminant neurolisteriosis: a comparative study (Swiss National Science Foundation, Sinergia)
Neurolisteriosis is a common and frequently fatal complication of Listeria monocytogenes infection in human and ruminants. It has a high impact on human and animal health, but only little is known about its pathogenesis. […]
Genomic and nomenclature databases of pathogenic bacterial strains
The genomic and nomenclature databases of strains of pathogenic bacterial species are available through the Institut Pasteur BIGSdb portal: http://bigsdb.pasteur.fr. The portal is powered by the Bacterial Isolates Genome Sequence DataBase (BIGSdb) tool developed […]
2011: PhD Biology, University of Aveiro, Aveiro, Portugal (approved unanimously).
2004: BSc Biology, University of Aveiro, Aveiro, Portugal (final classification of 16 out of 20).
Complementary Education in Computational Biology
2013: GTPB Course on Automated and Reproducible Analysis of NGS data – Instituto Gulbenkian de Ciência, Oeiras, Portugal.
2012: GTPB Course on Bioinformatics using Python – Instituto Gulbenkian de Ciência, Oeiras, Portugal.
2011: EMBO Course on Bioinformatics and Comparative Genomic Analysis – Institut Pasteur, Paris, France.
2014-present: Contract Researcher, Biology of Infection Unit & Evolutionary Microbial Genomics Unit, Institut Pasteur, Paris, France.
2011-2014: Postdoctoral Fellow, Centre for Environmental and Marine Studies, University of Aveiro, Portugal & Institute of Biomedical Research, University of Lleida, Spain. “Genomic signatures of environmental adaptation in prokaryotes” (SFRH/BPD/72256/2010).
2010-2011: Research Student, Centre for Neuroscience and Cell Biology, University of Coimbra, Portugal. “Reconstruction and systems analysis of the reaction networks of reactive oxygen, nitrogen and sulfur species in representative physiological systems” (PTDC/QUI/70523/2006/BI7).
2009-2010: Research Student, Institute of Biomedical Research, University of Lleida, Spain. “Reconstruction and systems analysis of the reaction networks of reactive oxygen, nitrogen and sulfur species in representative physiological systems” (PTDC/QUI/70523/2006/BI3).
2009: Supplemental Training on Plasmid Transfer and Replicon Typing, Julius Kühn Institute – Institute for Epidemiology and Pathogens Diagnostics, Braunschweig, Germany.
2005-2009: PhD student, Centre for Environmental and Marine Studies, Department of Biology, University of Aveiro, Portugal. “Molecular diversity and transferability of integrons in wastewater environments” (SFRH/BD/19433/2004).
2004: Research Student, Centre for Environmental and Marine Studies, Department of Biology, University of Aveiro, Portugal.“The prokaryotic flexible gene pool: integrons from environmental origin” (POCTI/BME/45881/2002/BI).
2003-2004: Trainee, Department of Biology, University of Aveiro, Portugal.“Abundance and diversity of bacterial communities in natural environments.”
2003-2004: Technician, Centre for Coastal and Maritime Zones, Department of Biology, University of Aveiro, Portugal. “Monitoring of water quality in Ria de Aveiro estuarine system.”
2002-2003: Final Year Project in Microbiology and Genetics, Department of Biology, University of Aveiro, Portugal. “Environmental metagenomes as antibiotic resistance reservoirs: development and validation of a PCR- and hybridization-based detection systems for beta-lactamase genes”, “Genomic location of beta-lactam resistance genes in Serratia fonticola UTAD54.”
Membership of scientific societies
Since 2012: Member of European Society of Clinical Microbiology and Infectious Diseases.
Since 2012: Member of American Society for Microbiology.
Since 2010: Member of International Society for Computational Biology.
Since 2004: Member of Society for General Microbiology.
Commissions of trust
Since 2012: Invited editor for Dataset Papers in Science (Bioinformatics section).
Since 2007: Regular invited reviewer for Nucleic Acids Research, Database, Journal of Antimicrobial Chemotherapy, Trends in Ecology & Evolution, Scientific Reports, Bioresource Technology, International Journal of Infectious Diseases, Journal of Hazardous Materials, Water Research, Ecological Indicators, Applied and Environmental Microbiology, PLoS One, International Journal of Molecular Sciences, Marine Drugs, FEMS Microbial Ecology, Environmental Science and Pollution Research, Applied Microbiology and Biotechnology, Antonie van Leeuwenhoek Journal of Microbiology, Current Microbiology, Archives of Environmental and Occupational Health, African Journal of Biotechnology, African Journal of Microbiology Research, Annals of Clinical Microbiology and Antimicrobials.
19 ISI papers; 800+ citations; h-index 13 [link]
2016Whole genome-based population biology and epidemiological surveillance of Listeria monocytogenes, Nat Microbiol 2016 Oct;2:16185.
2014The contribution of Escherichia coli from human and animal sources to the integron gene pool in coastal waters, Front Microbiol 2014;5:419.
2013Relative amino acid composition signatures of organisms and environments, PLoS ONE 2013;8(10):e77319.
2013Co-resistance to different classes of antibiotics among ESBL-producers from aquatic systems, Water Res. 2014 Jan;48:100-7.
2013Comparative genomics of IncP-1ε plasmids from water environments reveals diverse and unique accessory genetic elements, Plasmid 2013 Nov;70(3):412-9.
2012Diversity of gene cassette promoters in class 1 integrons from wastewater environments, Appl. Environ. Microbiol. 2012 Aug;78(15):5413-6.
2012Broad diversity of conjugative plasmids in integron-carrying bacteria from wastewater environments, FEMS Microbiol. Lett. 2012 May;330(2):157-64.
2011Novel gene cassettes and integrons in antibiotic-resistant bacteria isolated from urban wastewaters, Res. Microbiol. 2012 Feb;163(2):92-100.
2009Wastewater bacterial communities bring together broad-host range plasmids, integrons and a wide diversity of uncharacterized gene cassettes, Res. Microbiol. 2010 Jan-Feb;161(1):58-66.
2009Changes in the bacterial community structure in two-stage constructed wetlands with different plants for industrial wastewater treatment, Bioresour. Technol. 2009 Jul;100(13):3228-35.
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