The Unit of Biology of Emerging Viral Infections (UBIVE) was created in 2001 to develop expertise in research, surveillance, diagnosis and prevention of viral zoonoses inducing mostly hemorrhagic fevers in humans. In metropolitan France, UBIVE is the only Institut Pasteur (IP) Unit out of the Parisian campus. It is located in Lyon because of the presence of the BSL4 Laboratory Jean Mérieux-Inserm. UBIVE hosts the National Reference Center (NRC) for Viral Hemorrhagic Fevers and the NRC for Hantavirus.
Project: Immune responses and pathogenesis of Lassa fever
-Summary of the previous studies The main research effort of UBIVE is devoted to Lassa fever (LF), a viral hemorrhagic fever (VHF) endemic in West Africa and responsible for 300,000 cases and 5,000 deaths […]
2019Immune parameters and outcomes during Ebola virus disease, JCI Insight. 2019 Jan 10;4(1). pii: 125106.
2015Severe Ebola Virus Infection With Encephalopathy: Evidence for Direct Virus Involvement, Clin. Infect. Dis. 2015 Jul;.
2015Towards deep insight into Ebola virus disease, Lancet Infect Dis 2015 Jul;.
2015Ebola virus in West Africa: new conquered territories and new risks-or how I learned to stop worrying and (not) love Ebola virus, Curr Opin Virol 2015 Feb;10:70-6.
2015Identification of essential outstanding questions for an adequate European laboratory response to Ebolavirus Zaire West Africa 2014, J. Clin. Virol. 2015 Jan;62:124-34.
2014Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014, Viruses 2014 Nov;6(11):4760-99.
2014Ebola: should we consider influenza vaccination?, Lancet 2014 Dec;384(9959):2023-4.
2014Exonuclease domain of the Lassa virus nucleoprotein is critical to avoid RIG-I signaling and to inhibit the innate immune response, J. Virol. 2014 Dec;88(23):13923-7.
2014The exonuclease domain of Lassa virus nucleoprotein is involved in antigen-presenting-cell-mediated NK cell responses, J. Virol. 2014 Dec;88(23):13811-20.
2014Emergence of Zaire Ebola virus disease in Guinea, N. Engl. J. Med. 2014 Oct;371(15):1418-25.
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