Timeline

Pablo Pereira Esteva

Permanent Researcher

04 Sep 2023

team

Group : Hematopoietic Development

03 Mar 2023

publication

Assembling the layers of the hematopoietic system: A window of opportunity for thymopoiesis in the embryo.

06 Sep 2020

publication

A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner.

01 Jan 2020

publication

Hematopoiesis: A Layered Organization Across Chordate Species.

26 Apr 2019

publication

New Molecular Insights into Immune Cell Development

21 Aug 2017

publication

Asynchronous lineage priming determines commitment to T cell and B cell lineages in fetal liver

15 Sep 2016

publication

Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments

20 May 2016

publication

Fetal B cell development

01 Jul 2015

project

T cell development

09 Jun 2015

publication

Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays

02 Dec 2014

publication

Conformational changes in the T cell receptor differentially determine T cell subset development in mice

08 Dec 2013

publication

Two waves of distinct hematopoietic progenitor cells colonize the fetal thymus

05 Aug 2013

publication

Origin, trafficking, and intraepithelial fate of gut-tropic T cells

12 Jul 2013

publication

Critical role of TCR specificity in the development of Vγ1Vδ6.3+ innate NKTγδ cells

23 May 2012

publication

Differential requirement of RasGRP1 for γδ T cell development and activation

01 May 2012

publication

Innate NKTγδ and NKTαβ cells exert similar functions and compete for a thymic niche

11 Jan 2012

publication

Temporal predisposition to αβ and γδ T cell fates in the thymus

07 Mar 2011

publication

Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy

01 Oct 2010

publication

Cutting edge: Thymic NK cells develop independently from T cell precursors

19 Feb 2010

publication

Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent “innate” gammadelta T cells

28 Dec 2009

publication

Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3

15 Jul 2009

publication

TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity

01 Jul 2009

publication

Mechanisms determining cell membrane expression of different gammadelta TCR chain pairings

01 Mar 2007

publication

Reply to ‘Alice Dautry’ profile

01 Apr 2005

publication

Antigen recognition determinants of gammadelta T cell receptors

01 Apr 2005

publication

Mechanisms controlling termination of V-J recombination at the TCRgamma locus: implications for allelic and isotypic exclusion of TCRgamma chains

29 Dec 2004

publication

Stochastic modeling of T cell receptor gamma gene rearrangement

01 Sep 2004

publication

Rates of recombination and chain pair biases greatly influence the primary gammadelta TCR repertoire in the thymus of adult mice

15 Aug 2004

publication

Early expression of a functional TCRbeta chain inhibits TCRgamma gene rearrangements without altering the frequency of TCRgammadelta lineage cells

01 Sep 2003

publication

Most IL-4-producing gamma delta thymocytes of adult mice originate from fetal precursors

01 Oct 2002

publication

T cell receptor-gamma allele-specific selection of V gamma 1/V delta 4 cells in the intestinal epithelium

01 Jan 2001

publication

Strain-specific TCR repertoire selection of IL-4-producing Thy-1 dull gamma delta thymocytes

01 Jul 2000

publication

Genetic mapping of two murine loci that influence the development of IL-4-producing Thy-1dull gamma delta thymocytes

01 Jul 2000

publication

Developmentally regulated and lineage-specific rearrangement of T cell receptor Valpha/delta gene segments

15 Sep 1999

publication

IL-4-producing gamma delta T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen

01 Nov 1998

publication

The homogeneity of the TCRdelta repertoire expressed by the Thy-1dull gammadelta T cell population is due to cellular selection

22 May 1998

publication

Requirement for gammadelta T cells in allergic airway inflammation

20 Oct 1997

publication

The common cytokine receptor gamma chain controls survival of gamma/delta T cells

27 May 1997

publication

The T cell receptor repertoire of intestinal intraepithelial gammadelta T lymphocytes is influenced by genes linked to the major histocompatibility complex and to the T cell receptor loci

01 Feb 1997

publication

A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire

10 Dec 1996

publication

Expression of alpha v and beta 3 integrin chains on murine lymphocytes

01 Aug 1996

publication

Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium

01 Jan 1996

publication

Rearrangement and expression of Vzeta1, Vzeta2 and Vzeta3 TCR zeta genes in C57BL/6 mice

01 Dec 1995

publication

Ontogenic development and tissue distribution of V gamma 1-expressing gamma/delta T lymphocytes in normal mice

01 Sep 1995

publication

Regulatory T cells in thymic epithelium-induced tolerance. I. Suppression of mature peripheral non-tolerant T cells

15 Sep 1993

publication

Gamma delta T cells differentiate into a functional but nonproliferative state during a normal immune response

01 Jan 1992

publication

Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice

01 Nov 1991

publication

Post- thymic in vivo expansion of mature alpha beta T cells

01 Aug 1991

publication

Selective expansion of idiotype sharing T and B cells in cyclosporin A-mediated autoimmunity

01 Oct 1990

publication

A monoclonal anti-idiotypic antibody against the antigen-combining site of anti-factor VIII autoantibodies defines and idiotope that is recognized by normal human polyspecific immunoglobulins for therapeutic use (IVIg)

01 Dec 1989

publication

I-E-linked control of spontaneous rheumatoid factor production in normal mice

01 Nov 1989

publication

Further evidence for coelomic-associated B lymphocytes

01 Oct 1989

publication

Major histocompatibility complex-linked and T cell-dependent selection of antibody repertoires. Quantitation of I-E-related specificities in normal mice

01 May 1989

publication

Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

01 Jan 1989

publication

Preferential expansion of Ly-1 B and CD4- CD8- T cells in the polyclonal lymphocyte responses to murine T. cruzi infection

01 Jan 1989

publication

Selection of lymphocyte repertoires: the limits of clonal versus network organization

01 Jan 1989

publication

A model system for the analysis of B-cell activation and effector T-cell functions. T cell-dependent B-cell responses facilitated by anti-I-A antibodies

01 Jan 1989

publication

V-region connectivity in T cell repertoires

01 Dec 1988

publication

Back-stimulation of B lymphocytes binding to helper T cell surface antigens

01 Nov 1988

publication

Most B cells in acute Trypanosoma cruzi infection lack parasite specificity

01 Oct 1988

publication

T cell dependence of the “natural” autoreactive B cell activation in the spleen of normal mice

01 Jul 1988

publication

B cell participation in the recursive selection of T cell repertoires

01 Jun 1988

publication

Suppressor versus cytolytic CD8+ T lymphocytes: where are the artefacts?

01 Mar 1988

publication

The origin of “natural antibodies” and the internal activity in the immune system

01 Jan 1988

publication

The participation of B cells and antibodies in the selection and maintenance of T cell repertoires

01 Sep 1987

publication

A common idiotope on T cell receptors and antibodies expressed in the absence of network selection

15 Jul 1987

publication

Suppression of polyclonal antibody production in Trypanosoma cruzi-infected mice by treatment with anti-L3T4 antibodies

01 Jul 1987

publication

“In vivo” activated splenic T cells are refractory to interleukin 2 growth “in vitro”

01 Jun 1987

publication

A functional idiotypic network of T helper cells and antibodies, limited to the compartment of “naturally” activated lymphocytes in normal mice

01 Jun 1987

publication

Turning (Ir gene) low responders into high responders by antibody manipulation of the developing immune system

01 Jan 1987

publication

Sporadic idiotypic cross-reactivities between antibodies and T helper cells: one example of aleatory expression of T cell idiotypes

01 Jun 1986

publication

Autonomous activation of B and T cells in antigen-free mice

01 Apr 1986

publication

The role of immunoglobulin receptors in “cognate” T-B cell collaboration

01 Apr 1986

publication

The basis for major histocompatibility complex (MHC) and immunoglobulin gene control of helper T cell idiotopes

01 Jan 1986

publication

The mutual selective influences of T- and B-cell repertoires: the idiotypic net (at) work

01 Jan 1986

publication

Functional and biochemical evidence for the recognition of T cell receptors by monoclonal antibodies to an immunoglobulin idiotype

01 Nov 1985

publication

Natural effector T lymphocytes in normal mice

24 Oct 1985

publication

Establishment of idiotypic helper T-cell repertoires early in life

01 Sep 1985

publication

Interactions of small B lymphocytes with unprimed noncytolytic T cells: dissociation between “presentation” and growth induction

01 Apr 1985

publication

Modulation of cytolytic T cell function by lectins

01 Jul 1984

publication

Internal complementarities in the immune system: regulation of the expression of helper T-cell idiotypes

01 Apr 1984

publication

A little guide for advanced search:

Group : Hematopoietic Development

Assembling the layers of the hematopoietic system: A window of opportunity for thymopoiesis in the embryo.

A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner.

Hematopoiesis: A Layered Organization Across Chordate Species.

New Molecular Insights into Immune Cell Development

Asynchronous lineage priming determines commitment to T cell and B cell lineages in fetal liver

Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments

Fetal B cell development

T cell development

Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays

Conformational changes in the T cell receptor differentially determine T cell subset development in mice

Two waves of distinct hematopoietic progenitor cells colonize the fetal thymus

Origin, trafficking, and intraepithelial fate of gut-tropic T cells

Critical role of TCR specificity in the development of Vγ1Vδ6.3+ innate NKTγδ cells

Differential requirement of RasGRP1 for γδ T cell development and activation

Innate NKTγδ and NKTαβ cells exert similar functions and compete for a thymic niche

Temporal predisposition to αβ and γδ T cell fates in the thymus

Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy

Cutting edge: Thymic NK cells develop independently from T cell precursors

Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent “innate” gammadelta T cells

Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3

TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity

Mechanisms determining cell membrane expression of different gammadelta TCR chain pairings

Reply to ‘Alice Dautry’ profile

Antigen recognition determinants of gammadelta T cell receptors

Mechanisms controlling termination of V-J recombination at the TCRgamma locus: implications for allelic and isotypic exclusion of TCRgamma chains

Stochastic modeling of T cell receptor gamma gene rearrangement

Rates of recombination and chain pair biases greatly influence the primary gammadelta TCR repertoire in the thymus of adult mice

Early expression of a functional TCRbeta chain inhibits TCRgamma gene rearrangements without altering the frequency of TCRgammadelta lineage cells

Most IL-4-producing gamma delta thymocytes of adult mice originate from fetal precursors

T cell receptor-gamma allele-specific selection of V gamma 1/V delta 4 cells in the intestinal epithelium

Strain-specific TCR repertoire selection of IL-4-producing Thy-1 dull gamma delta thymocytes

Genetic mapping of two murine loci that influence the development of IL-4-producing Thy-1dull gamma delta thymocytes

Developmentally regulated and lineage-specific rearrangement of T cell receptor Valpha/delta gene segments

IL-4-producing gamma delta T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen

The homogeneity of the TCRdelta repertoire expressed by the Thy-1dull gammadelta T cell population is due to cellular selection

Requirement for gammadelta T cells in allergic airway inflammation

The common cytokine receptor gamma chain controls survival of gamma/delta T cells

The T cell receptor repertoire of intestinal intraepithelial gammadelta T lymphocytes is influenced by genes linked to the major histocompatibility complex and to the T cell receptor loci

A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire

Expression of alpha v and beta 3 integrin chains on murine lymphocytes

Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium

Rearrangement and expression of Vzeta1, Vzeta2 and Vzeta3 TCR zeta genes in C57BL/6 mice

Ontogenic development and tissue distribution of V gamma 1-expressing gamma/delta T lymphocytes in normal mice

Regulatory T cells in thymic epithelium-induced tolerance. I. Suppression of mature peripheral non-tolerant T cells

Gamma delta T cells differentiate into a functional but nonproliferative state during a normal immune response

Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice

Post- thymic in vivo expansion of mature alpha beta T cells

Selective expansion of idiotype sharing T and B cells in cyclosporin A-mediated autoimmunity

A monoclonal anti-idiotypic antibody against the antigen-combining site of anti-factor VIII autoantibodies defines and idiotope that is recognized by normal human polyspecific immunoglobulins for therapeutic use (IVIg)

I-E-linked control of spontaneous rheumatoid factor production in normal mice

Further evidence for coelomic-associated B lymphocytes

Major histocompatibility complex-linked and T cell-dependent selection of antibody repertoires. Quantitation of I-E-related specificities in normal mice

Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

Preferential expansion of Ly-1 B and CD4- CD8- T cells in the polyclonal lymphocyte responses to murine T. cruzi infection

Selection of lymphocyte repertoires: the limits of clonal versus network organization

A model system for the analysis of B-cell activation and effector T-cell functions. T cell-dependent B-cell responses facilitated by anti-I-A antibodies

V-region connectivity in T cell repertoires

Back-stimulation of B lymphocytes binding to helper T cell surface antigens

Most B cells in acute Trypanosoma cruzi infection lack parasite specificity

T cell dependence of the “natural” autoreactive B cell activation in the spleen of normal mice

B cell participation in the recursive selection of T cell repertoires

Suppressor versus cytolytic CD8+ T lymphocytes: where are the artefacts?

The origin of “natural antibodies” and the internal activity in the immune system

The participation of B cells and antibodies in the selection and maintenance of T cell repertoires

A common idiotope on T cell receptors and antibodies expressed in the absence of network selection

Suppression of polyclonal antibody production in Trypanosoma cruzi-infected mice by treatment with anti-L3T4 antibodies

“In vivo” activated splenic T cells are refractory to interleukin 2 growth “in vitro”

A functional idiotypic network of T helper cells and antibodies, limited to the compartment of “naturally” activated lymphocytes in normal mice

Turning (Ir gene) low responders into high responders by antibody manipulation of the developing immune system

Sporadic idiotypic cross-reactivities between antibodies and T helper cells: one example of aleatory expression of T cell idiotypes

Autonomous activation of B and T cells in antigen-free mice

The role of immunoglobulin receptors in “cognate” T-B cell collaboration

The basis for major histocompatibility complex (MHC) and immunoglobulin gene control of helper T cell idiotopes

The mutual selective influences of T- and B-cell repertoires: the idiotypic net (at) work

Functional and biochemical evidence for the recognition of T cell receptors by monoclonal antibodies to an immunoglobulin idiotype

Natural effector T lymphocytes in normal mice

Establishment of idiotypic helper T-cell repertoires early in life

Interactions of small B lymphocytes with unprimed noncytolytic T cells: dissociation between “presentation” and growth induction