Timeline

Paulo Vieira

Group Leader

26 Oct 2021

publication

Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis.

06 Sep 2020

publication

A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner.

01 Jun 2020

publication

Beware of whom you live with: Your intestinal IgA may depend on it.

14 Oct 2019

publication

Biology and therapeutic potential of interleukin-10

07 May 2019

event

Department of Immunology seminar: Franck J. Barrat, TLRs and pDCs in inflammation and Disease

12 Jun 2018

event

The consequences of not being good whiskey : IL-7 in leukomogenesis

01 Mar 2018

publication

The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis

01 Oct 2017

publication

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

21 Aug 2017

publication

Asynchronous lineage priming determines commitment to T cell and B cell lineages in fetal liver

06 Jun 2017

publication

Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune system

15 Mar 2017

event

Dinis Calado seminar

13 Feb 2017

publication

Essential role of immobilized chemokine CXCL12 in the regulation of the humoral immune response

20 May 2016

publication

Fetal B cell development

18 May 2016

project

Gene expression profiling in germinal center B cells

09 Sep 2015

project

The role of a gradient of the chemokine CXCL12 in hematopoietic development and in a normal immune response. (Collaboration with F. Arenzana-Seisdedos, granted ANR funding)

16 Jul 2015

team

Group: Humoral Immunity

01 Jul 2015

project

Deregulation of hematopoiesis by Interleukin-10 over-expression (Joint project with the University of Minho, Portugal, granted ANR international funding)

11 Mar 2015

publication

Immune quiescence of the brain is set by astroglial connexin 43

17 Dec 2014

publication

Independent recruitment of Igh alleles in V(D)J recombination

11 Jun 2014

publication

Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis

25 Jan 2014

publication

Hematopoiesis during embryonic development

08 Dec 2013

publication

Two waves of distinct hematopoietic progenitor cells colonize the fetal thymus

03 Oct 2012

publication

Homeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions

12 Sep 2012

publication

Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors

16 Apr 2010

publication

CpG inhibits pro-B cell expansion through a cathepsin B-dependent mechanism

13 Mar 2010

publication

Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age

08 Feb 2010

publication

IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors

19 May 2009

publication

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7

18 Apr 2008

publication

IL-10 modulates depressive-like behavior

15 Nov 2007

publication

The Bw cells, a novel B cell population conserved in the whole genus Mus

01 Sep 2007

publication

Regula’ten’ the gut

01 Jun 2007

publication

T(H)1 cells control themselves by producing interleukin-10

01 Mar 2007

publication

Reply to ‘Alice Dautry’ profile

01 Dec 2006

publication

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals

08 Jun 2006

publication

Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7

14 Mar 2005

publication

Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors

01 Nov 2004

publication

IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage

27 Sep 2004

publication

Regulatory potential and control of Foxp3 expression in newborn CD4+ T cells

01 Aug 2004

publication

Regulatory T cells and mechanisms of immune system control

19 Jul 2004

publication

Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment

01 Jan 2004

publication

Differentiation of B lymphocytes from hematopoietic stem cells

01 Oct 2003

publication

Organogenesis of peripheral lymphoid organs

20 Jul 2003

publication

Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development

01 Apr 2003

publication

Twenty-first century Foxp3

31 Mar 2003

publication

Monoallelic expression of the murine gene encoding Toll-like receptor 4

01 Dec 2002

publication

Lymphocyte commitment during embryonic development, in the mouse

01 Nov 2002

publication

Evidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55Pro

15 Oct 2001

publication

Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice

25 Jan 2001

publication

Organismos (Eucariotas) geneticamente manipulados

15 May 1995

publication

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells

01 Apr 1995

publication

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine

01 Jan 1993

publication

Interleukin-10

01 Apr 1992

publication

Polymerase chain reaction for detection of cytokine gene expression

15 May 1991

publication

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells

15 Feb 1991

publication

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI

01 Nov 1990

publication

Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1

01 Jun 1990

publication

Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI

25 Jan 1990

publication

Molecular biology of mouse and human cytokine synthesis inhibitory factor (CSIF; IL-10)

01 Jan 1990

publication

Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10

01 Jan 1990

publication

Persistence of memory B cells in mice deprived of T cell help

01 May 1989

publication

Membrane-bound IgM obstructs B cell development in transgenic mice

25 Jan 1989

publication

Heterogeneity of mouse helper T cells and cross-regulation of Th1 and Th2 clones.

01 Jan 1989

publication

Growth and selection of B cells in vivo

01 Jan 1989

publication

Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse

15 Dec 1988

publication

Effects of surgical stress on lymphoid populations of mice

01 Feb 1988

publication

The half-lives of serum immunoglobulins in adult mice

01 Jun 1987

publication

The majority of “natural” immunoglobulin-secreting cells are short-lived and the progeny of cycling lymphocytes

01 Nov 1986

publication

Effects of hydroxyurea in vivo treatment on the antibody response in mice

01 Jul 1986

publication

A little guide for advanced search:

Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis.

A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner.

Beware of whom you live with: Your intestinal IgA may depend on it.

Biology and therapeutic potential of interleukin-10

Department of Immunology seminar: Franck J. Barrat, TLRs and pDCs in inflammation and Disease

The consequences of not being good whiskey : IL-7 in leukomogenesis

The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Asynchronous lineage priming determines commitment to T cell and B cell lineages in fetal liver

Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune system

Dinis Calado seminar

Essential role of immobilized chemokine CXCL12 in the regulation of the humoral immune response

Fetal B cell development

Gene expression profiling in germinal center B cells

The role of a gradient of the chemokine CXCL12 in hematopoietic development and in a normal immune response. (Collaboration with F. Arenzana-Seisdedos, granted ANR funding)

Group: Humoral Immunity

Deregulation of hematopoiesis by Interleukin-10 over-expression (Joint project with the University of Minho, Portugal, granted ANR international funding)

Immune quiescence of the brain is set by astroglial connexin 43

Independent recruitment of Igh alleles in V(D)J recombination

Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis

Hematopoiesis during embryonic development

Two waves of distinct hematopoietic progenitor cells colonize the fetal thymus

Homeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions

Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors

CpG inhibits pro-B cell expansion through a cathepsin B-dependent mechanism

Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age

IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7

IL-10 modulates depressive-like behavior

The Bw cells, a novel B cell population conserved in the whole genus Mus

Regula’ten’ the gut

T(H)1 cells control themselves by producing interleukin-10

Reply to ‘Alice Dautry’ profile

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals

Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7

Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors

IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage

Regulatory potential and control of Foxp3 expression in newborn CD4+ T cells

Regulatory T cells and mechanisms of immune system control

Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment

Differentiation of B lymphocytes from hematopoietic stem cells

Organogenesis of peripheral lymphoid organs

Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development

Twenty-first century Foxp3

Monoallelic expression of the murine gene encoding Toll-like receptor 4

Lymphocyte commitment during embryonic development, in the mouse

Evidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55Pro

Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice

Organismos (Eucariotas) geneticamente manipulados

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine

Interleukin-10

Polymerase chain reaction for detection of cytokine gene expression

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI

Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1

Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI

Molecular biology of mouse and human cytokine synthesis inhibitory factor (CSIF; IL-10)

Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10

Persistence of memory B cells in mice deprived of T cell help

Membrane-bound IgM obstructs B cell development in transgenic mice

Heterogeneity of mouse helper T cells and cross-regulation of Th1 and Th2 clones.

Growth and selection of B cells in vivo

Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse

Effects of surgical stress on lymphoid populations of mice

The half-lives of serum immunoglobulins in adult mice

The majority of “natural” immunoglobulin-secreting cells are short-lived and the progeny of cycling lymphocytes

Effects of hydroxyurea in vivo treatment on the antibody response in mice

The bulk of endogenously produced IgG2a is eliminated from the serum of adult C57BL/6 mice with a half-life of 6-8 days