Timeline

Michael Nilges
Head of Structure
26 Sep 2024
event

Workshop of The Structural Bioinformatics Unit

Read more
05 Jul 2024
publication

Structure and Dynamics of Type 4a Pili and Type 2 Secretion System Endopili

Read more
30 Apr 2024
event

Roles of core facilities in institutional and regional R&D&I, and management practices

Read more
20 Apr 2024
publication

A comprehensive dataset of protein-protein interactions and ligand binding pockets for advancing drug discovery

Read more
25 Aug 2023
event

DBSC workshop “Optimal Prediction of Protein Complex Structures with AlphaFold Made Easy” on September 26th

Read more
22 Jun 2023
event

Single-Domain Antibodies 2023

Read more
02 Feb 2023
publication

Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.

Read more
01 Feb 2023
news

Bacterial pathogenicity: improving understanding of an essential process – molecule secretion

Read more
27 Jan 2023
event

NMR: a tool for biology XIIIth

Read more
13 Sep 2022
publication

Building Protein Atomic Models from Cryo-EM Density Maps and Residue Co-Evolution.

Read more
11 Sep 2022
project

Energir: Energy dependent iron import by Gram-negative bacteria

Read more
28 Apr 2022
publication

Secondary structure and 1H, 15 N & 13C resonance assignments of the periplasmic domain of OutG, major pseudopilin from Dickeya dadantii type II secretion system.

Read more
14 Apr 2022
publication

Bat coronaviruses related to SARS-CoV-2 and infectious for human cells.

Read more
16 Mar 2022
event

Half-day Latest innovations and Applications in CryoEM& CryoET

Read more
15 Dec 2021
publication

InDeep: 3D fully convolutional neural networks to assist in silico drug design on protein-protein interactions.

Read more
01 Oct 2021
publication

1 H, 15 N and 13 C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system

Read more
11 Sep 2021
publication

Computational and biochemical analysis of type IV pilus dynamics and stability.

Read more
14 Jul 2021
publication

Host-Pathogen Adhesion as the Basis of Innovative Diagnostics for Emerging Pathogens.

Read more
08 Jan 2021
publication

The iPPI-DB initiative: a community-centered database of protein-protein interaction modulators.

Read more
22 Jun 2020
event

NMR: a tool for Biology XIIth

Read more
21 Apr 2020
tool

ARIAweb: a server for automated NMR structure calculation

Read more
19 Nov 2019
event

Thesis defense: Borja Rodriguez de Francisco – “Self-assembly into functional amyloids of Aspergillus fumigatus hydrophobins”

Read more
03 Oct 2019
event

Department of Structural Biology and Chemistry seminar: James Conway, Probing the common architectures of bacteriophage T5 and herpesvirus by cryo-electron microscopy

Read more
31 Jul 2019
project

Synergy_T2SS

Read more
23 May 2019
publication

Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches

Read more
09 Apr 2019
publication

Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus.

Read more
26 Jan 2019
event

11th Conference “NMR: a tool for Biology”, 28-30 Jan 2019

Read more
24 Jan 2019
patent

Docking method based on saturation transfer difference NMR data, and means for its implementation WO 2019/011987

Read more
01 Jan 2019
publication

Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling

Read more
18 Dec 2018
publication

Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR.

Read more
04 Sep 2018
event

Binless: bayesian normalization of Hi-C data provides significant interaction and difference detection independently of resolution

Read more
29 May 2018
event

Half-Day Symposium “NMR Beyond Protein Structures”

Read more
16 Mar 2018
publication

Ordering Protein Contact Matrices

Read more
09 Mar 2018
publication

Tuning interval Branch-and-Prune for protein structure determination

Read more
28 Nov 2017
project

ViBrANT (Viral and Bacterial Adhesin Network Training)

Read more
15 May 2017
event

“NMR in drug discovery” – Dr Wolfgang JAHNKE

Read more
13 Mar 2017
event

Jane Clarke seminar

Read more
10 Mar 2017
event

Pr. Timothy DAFFORN seminar

Read more
02 Mar 2016
project

ARIA for hybrid structure determination on the cloud

Read more
05 Jan 2016
publication

Structure determination of helical filaments by solid-state NMR spectroscopy

Read more
16 Oct 2015
project

AEGIS (Accelerated Early staGe drug dIScovery)

Read more
08 Oct 2015
team

Tech Lab

Read more
14 Sep 2015
publication

Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation

Read more
31 Aug 2015
project

Binding mode of promising antituberculosis clinical compounds to their bacterial target

Read more
23 Jul 2015
software

ARIA (Ambiguous Restraints for Iterative Assignment)

Read more
22 Jul 2015
project

FiberSpace

Read more
22 Jul 2015
publication

Biogenesis and structure of a type VI secretion membrane core complex

Read more
07 Jul 2015
project

ERC-2011-AdG BAYCELLS

Read more
07 Jul 2015
project

Bip:Bip

Read more
07 Jul 2015
project

CACSICE

Read more
11 May 2015
team

Structural Bioinformatics

Read more
11 Apr 2015
publication

Improved reliability, accuracy and quality in automated NMR structure calculation with ARIA

Read more
26 Dec 2014
publication

An automatic tool to analyze and cluster macromolecular conformations based on self-organizing maps

Read more
14 Sep 2014
publication

Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG

Read more
31 May 2012
publication

Efficient modeling of symmetric protein aggregates from NMR data

Read more
01 Jan 2012
publication

ARIA for solution and solid-state NMR

Read more
05 May 2011
publication

Grid computing for improving conformational sampling in NMR structure calculation

Read more
01 Mar 2011
publication

Bayesian estimation of NMR restraint potential and weight: a validation on a representative set of protein structures

Read more
28 Jun 2010
publication

Structural insights into serine-rich fimbriae from Gram-positive bacteria

Read more
09 Jun 2010
publication

Simultaneous use of solution, solid-state NMR and X-ray crystallography to study the conformational landscape of the Crh protein during oligomerization and crystallization

Read more
15 May 2009
publication

Influence of different assignment conditions on the determination of symmetric homodimeric structures with ARIA

Read more
01 Apr 2009
publication

Insights into the enzymatic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei using structural data and molecular dynamics simulation

Read more
10 Sep 2008
publication

Accurate NMR structures through minimization of an extended hybrid energy

Read more
05 Jun 2008
publication

Graphical analysis of NMR structural quality and interactive contact map of NOE assignments in ARIA

Read more
20 Feb 2008
publication

3D structure determination of the Crh protein from highly ambiguous solid-state NMR restraints

Read more
22 Nov 2006
publication

ARIA2: automated NOE assignment and data integration in NMR structure calculation

Read more
22 Nov 2006
publication

Three dimensional structure and implications for the catalytic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei

Read more
01 Sep 2006
publication

Determination of dihedral Psi angles in large proteins by combining NH(N)/C(alpha)H(alpha) dipole/dipole cross-correlation and chemical shifts

Read more
01 Mar 2006
publication

Comparison of different torsion angle approaches for NMR structure determination

Read more
01 Apr 2005
publication

Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

Read more