Timeline
Michael Nilges
Head of Structure
26 Sep 2024
05 Jul 2024
30 Apr 2024
event
Roles of core facilities in institutional and regional R&D&I, and management practices
Read more20 Apr 2024
publication
A comprehensive dataset of protein-protein interactions and ligand binding pockets for advancing drug discovery
Read more25 Aug 2023
event
DBSC workshop “Optimal Prediction of Protein Complex Structures with AlphaFold Made Easy” on September 26th
Read more22 Jun 2023
02 Feb 2023
publication
Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.
Read more01 Feb 2023
news
Bacterial pathogenicity: improving understanding of an essential process – molecule secretion
Read more27 Jan 2023
13 Sep 2022
publication
Building Protein Atomic Models from Cryo-EM Density Maps and Residue Co-Evolution.
Read more11 Sep 2022
28 Apr 2022
publication
Secondary structure and 1H, 15 N & 13C resonance assignments of the periplasmic domain of OutG, major pseudopilin from Dickeya dadantii type II secretion system.
Read more14 Apr 2022
16 Mar 2022
15 Dec 2021
publication
InDeep: 3D fully convolutional neural networks to assist in silico drug design on protein-protein interactions.
Read more01 Oct 2021
publication
1 H, 15 N and 13 C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system
Read more11 Sep 2021
publication
Computational and biochemical analysis of type IV pilus dynamics and stability.
Read more14 Jul 2021
publication
Host-Pathogen Adhesion as the Basis of Innovative Diagnostics for Emerging Pathogens.
Read more08 Jan 2021
publication
The iPPI-DB initiative: a community-centered database of protein-protein interaction modulators.
Read more22 Jun 2020
21 Apr 2020
19 Nov 2019
event
Thesis defense: Borja Rodriguez de Francisco – “Self-assembly into functional amyloids of Aspergillus fumigatus hydrophobins”
Read more03 Oct 2019
event
Department of Structural Biology and Chemistry seminar: James Conway, Probing the common architectures of bacteriophage T5 and herpesvirus by cryo-electron microscopy
Read more31 Jul 2019
23 May 2019
publication
Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches
Read more09 Apr 2019
publication
Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus.
Read more26 Jan 2019
24 Jan 2019
patent
Docking method based on saturation transfer difference NMR data, and means for its implementation WO 2019/011987
Read more01 Jan 2019
publication
Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling
Read more18 Dec 2018
publication
Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR.
Read more04 Sep 2018
event
Binless: bayesian normalization of Hi-C data provides significant interaction and difference detection independently of resolution
Read more29 May 2018
16 Mar 2018
09 Mar 2018
28 Nov 2017
15 May 2017
13 Mar 2017
10 Mar 2017
02 Mar 2016
05 Jan 2016
16 Oct 2015
08 Oct 2015
14 Sep 2015
publication
Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation
Read more31 Aug 2015
project
Binding mode of promising antituberculosis clinical compounds to their bacterial target
Read more23 Jul 2015
22 Jul 2015
22 Jul 2015
07 Jul 2015
07 Jul 2015
07 Jul 2015
11 May 2015
11 Apr 2015
publication
Improved reliability, accuracy and quality in automated NMR structure calculation with ARIA
Read more26 Dec 2014
publication
An automatic tool to analyze and cluster macromolecular conformations based on self-organizing maps
Read more14 Sep 2014
publication
Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG
Read more31 May 2012
01 Jan 2012
05 May 2011
publication
Grid computing for improving conformational sampling in NMR structure calculation
Read more01 Mar 2011
publication
Bayesian estimation of NMR restraint potential and weight: a validation on a representative set of protein structures
Read more28 Jun 2010
09 Jun 2010
publication
Simultaneous use of solution, solid-state NMR and X-ray crystallography to study the conformational landscape of the Crh protein during oligomerization and crystallization
Read more15 May 2009
publication
Influence of different assignment conditions on the determination of symmetric homodimeric structures with ARIA
Read more01 Apr 2009
publication
Insights into the enzymatic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei using structural data and molecular dynamics simulation
Read more10 Sep 2008
05 Jun 2008
publication
Graphical analysis of NMR structural quality and interactive contact map of NOE assignments in ARIA
Read more20 Feb 2008
publication
3D structure determination of the Crh protein from highly ambiguous solid-state NMR restraints
Read more22 Nov 2006
publication
ARIA2: automated NOE assignment and data integration in NMR structure calculation
Read more22 Nov 2006
publication
Three dimensional structure and implications for the catalytic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei
Read more01 Sep 2006
publication
Determination of dihedral Psi angles in large proteins by combining NH(N)/C(alpha)H(alpha) dipole/dipole cross-correlation and chemical shifts
Read more01 Mar 2006
publication
Comparison of different torsion angle approaches for NMR structure determination
Read more01 Apr 2005
publication