Timeline

Michael Nilges
Head of Structure
23 May 2019
publication

Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches

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09 Apr 2019
publication

Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus.

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26 Jan 2019
event

11th Conference “NMR: a tool for Biology”, 28-30 Jan 2019

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24 Jan 2019
patent

Docking method based on saturation transfer difference NMR data, and means for its implementation WO 2019/011987

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01 Jan 2019
publication

Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling

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18 Dec 2018
publication

Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR.

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04 Sep 2018
event

Binless: bayesian normalization of Hi-C data provides significant interaction and difference detection independently of resolution

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29 May 2018
event

Half-Day Symposium “NMR Beyond Protein Structures”

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16 Mar 2018
publication

Ordering Protein Contact Matrices

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09 Mar 2018
publication

Tuning interval Branch-and-Prune for protein structure determination

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28 Nov 2017
project

ViBrANT (Viral and Bacterial Adhesin Network Training)

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09 Oct 2017
publication

Structure of the calcium-dependent type 2 secretion pseudopilus

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15 May 2017
event

“NMR in drug discovery” – Dr Wolfgang JAHNKE

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13 Mar 2017
event

Jane Clarke seminar

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10 Mar 2017
event

Pr. Timothy DAFFORN seminar

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02 Mar 2016
project

ARIA for hybrid structure determination on the cloud

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05 Jan 2016
publication

Structure determination of helical filaments by solid-state NMR spectroscopy

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16 Oct 2015
project

AEGIS (Accelerated Early staGe drug dIScovery)

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14 Sep 2015
publication

Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation

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31 Aug 2015
project

Binding mode of promising antituberculosis clinical compounds to their bacterial target

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23 Jul 2015
software

ARIA (Ambiguous Restraints for Iterative Assignment)

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22 Jul 2015
project

FiberSpace

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22 Jul 2015
publication

Biogenesis and structure of a type VI secretion membrane core complex

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07 Jul 2015
project

ERC-2011-AdG BAYCELLS

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07 Jul 2015
project

Bip:Bip

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07 Jul 2015
project

CACSICE

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11 May 2015
team

Structural Bioinformatics

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11 Apr 2015
publication

Improved reliability, accuracy and quality in automated NMR structure calculation with ARIA

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28 Jan 2015
publication

An algorithm to enumerate all possible protein conformations verifying a set of distance constraints

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26 Dec 2014
publication

An automatic tool to analyze and cluster macromolecular conformations based on self-organizing maps

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15 Sep 2014
department

Structural Biology and Chemistry

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14 Sep 2014
publication

Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG

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31 May 2012
publication

Efficient modeling of symmetric protein aggregates from NMR data

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01 Jan 2012
publication

ARIA for solution and solid-state NMR

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01 Mar 2011
publication

Bayesian estimation of NMR restraint potential and weight: a validation on a representative set of protein structures

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28 Jun 2010
publication

Structural insights into serine-rich fimbriae from Gram-positive bacteria

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09 Jun 2010
publication

Simultaneous use of solution, solid-state NMR and X-ray crystallography to study the conformational landscape of the Crh protein during oligomerization and crystallization

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15 May 2009
publication

Influence of different assignment conditions on the determination of symmetric homodimeric structures with ARIA

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10 Sep 2008
publication

Accurate NMR structures through minimization of an extended hybrid energy

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05 Jun 2008
publication

Graphical analysis of NMR structural quality and interactive contact map of NOE assignments in ARIA

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20 Feb 2008
publication

3D structure determination of the Crh protein from highly ambiguous solid-state NMR restraints

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22 Nov 2006
publication

ARIA2: automated NOE assignment and data integration in NMR structure calculation

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01 Mar 2006
publication

Comparison of different torsion angle approaches for NMR structure determination

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