Timeline

Michaela Muller-Trutwin
Head of Structure
30 Nov 2021
news

Post-doc position

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07 Jun 2021
news

Immunothérapie permettant à des cellules du système immunitaire inné de contribuer au contrôle du VIH après un arrêt du traitement antiviral

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05 May 2021
publication

Ultrasensitive detection of p24 in plasma samples from people with primary and chronic HIV-1 infection.

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01 May 2021
publication

HIV DNA reservoir and elevated PD-1 expression of CD4 T-cell subsets particularly persist in the terminal ileum of HIV-positive patients despite cART.

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24 Feb 2021
publication

SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity.

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01 Jan 2021
publication

CD32+CD4+ T Cells Sharing B Cell Properties Increase With Simian Immunodeficiency Virus Replication in Lymphoid Tissues.

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09 Dec 2020
publication

DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections.

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22 Sep 2020
publication

Optimal Maturation of the SIV-Specific CD8+ T Cell Response after Primary Infection Is Associated with Natural Control of SIV: ANRS SIC Study.

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01 Sep 2020
publication

Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation.

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01 Jul 2020
publication

Antiapoptotic Clone 11-Derived Peptides Induce In Vitro Death of CD4+ T Cells Susceptible to HIV-1 Infection.

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01 Jul 2020
publication

Extremely low viral reservoir in treated chronically HIV-1-infected individuals.

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18 Jun 2020
publication

TLR7 dosage polymorphism shapes interferogenesis and HIV-1 acute viremia in women.

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01 Jan 2020
publication

Non-human Primate Determinants of Natural Killer Cells in Tissues at Steady-State and During Simian Immunodeficiency Virus Infection.

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19 Sep 2019
event

Recherche sur le VIH et les Hépatites: quels nouveaux enjeux?

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03 Sep 2019
event

France – Japan Symposium on HIV and hepatitis basic research

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01 Aug 2019
publication

Contribution of animal models to HIV research.

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01 Jul 2019
publication

Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection.

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01 Jun 2019
publication

The Yellow Brick Road towards HIV Eradication.

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01 May 2019
publication

NK cell immune responses differ after prime and boost vaccination.

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01 Apr 2019
publication

MDSCs in infectious diseases: regulation, roles, and readjustment.

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26 Mar 2019
news

ANRS AC41 Symposium- HIV Pathogenesis: Lessons from HIV-2

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05 Mar 2019
publication

Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4+ T Cells and Offers an Opportunity to Tackle Infection.

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01 Nov 2018
publication

Publisher Correction: Ancient hybridization and strong adaptation to viruses across African vervet monkey populations.

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01 Oct 2018
publication

Effect of schistosomiasis on the outcome of patients infected with HIV-1 starting antiretroviral therapy in rural Tanzania.

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20 Sep 2018
news

HIV DART and Emerging viruses meeting (deadline for abstracts Oct 5)

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27 Aug 2018
news

MOOC on HIV Science (registration free)

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03 Jul 2018
news

Satellite Symposium at the International HIV Conference in Amsterdam: ” How Far are We from HIV Remission?

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01 Jul 2018
publication

Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage.

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01 Jun 2018
publication

[Professional HIV testing].

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10 Apr 2018
publication

Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.

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09 Apr 2018
news

IDMI-DIM1Health Symposium

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01 Apr 2018
publication

Interferon-associated therapies toward HIV control: The back and forth.

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01 Jan 2018
publication

Lymph Node Cellular and Viral Dynamics in Natural Hosts and Impact for HIV Cure Strategies.

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01 Dec 2017
publication

Ancient hybridization and strong adaptation to viruses across African vervet monkey populations.

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01 Dec 2017
publication

High proportion of PD-1-expressing CD4+ T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence.

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01 Dec 2017
publication

p21 Restricts HIV-1 in Monocyte-Derived Dendritic Cells through the Reduction of Deoxynucleoside Triphosphate Biosynthesis and Regulation of SAMHD1 Antiviral Activity.

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17 Nov 2017
project

NK cells and viral reservoirs

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02 Nov 2017
news

Keystone symposium on HIV Pathogenesis, Inflammation and Persistence

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01 Nov 2017
publication

Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys.

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17 Oct 2017
news

Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys

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01 Jul 2017
publication

NKG2C+ memory-like NK cells contribute to the control of HIV viremia during primary infection: Optiprim-ANRS 147.

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15 Mar 2017
publication

Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents.

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15 Feb 2017
publication

CXCR6-Mediated Simian Immunodeficiency Virus SIVagmSab Entry into Sabaeus African Green Monkey Lymphocytes Implicates Widespread Use of Non-CCR5 Pathways in Natural Host Infections.

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09 Jan 2017
news

IAS 2017

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01 Jan 2017
publication

Impact of early cART on HIV blood and semen compartments at the time of primary infection.

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01 Jan 2017
publication

A Mature NK Profile at the Time of HIV Primary Infection Is Associated with an Early Response to cART.

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01 Dec 2016
publication

Non-human primates in HIV research: Achievements, limits and alternatives.

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01 Aug 2016
publication

Innate immune cell responses in non pathogenic versus pathogenic SIV infections.

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01 Aug 2016
publication

Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset.

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30 Apr 2016
news

IDMIT Symposium

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30 Apr 2016
news

HIV Cure Symposium

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03 Mar 2016
news

Let’s #cutAIDSshort

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01 Mar 2016
publication

Immune activation in HIV infection: what can the natural hosts of simian immunodeficiency virus teach us?

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12 Feb 2016
project

Group for AIDS Research

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12 Jan 2016
publication

Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells.

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01 Jan 2016
publication

Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles.

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01 Dec 2015
publication

The genome of the vervet (Chlorocebus aethiops sabaeus).

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08 Sep 2015
publication

NK cell exhaustion: bad news for chronic disease?

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08 Sep 2015
publication

Natural SIV Infection: Immunological Aspects

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04 Sep 2015
news

Intracellular immunity and the sensing of pathogens

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04 Sep 2015
project

VRI Labex

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04 Sep 2015
project

European Network on Myeloid Regulatory Cells

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03 Sep 2015
project

A model of control of chronic inflammation

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01 Sep 2015
publication

Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection.

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01 Jul 2015
publication

Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.

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01 Jul 2015
publication

Second European Round Table on the Future Management of HIV: 10-11 October 2014, Barcelona, Spain.

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11 May 2015
team

HIV, Inflammation and Persistence

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01 Apr 2015
publication

[Postexposure prophylaxis in daily clinical practice].

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01 Apr 2015
publication

Cryptococcal Antigenemia in Immunocompromised Human Immunodeficiency Virus Patients in Rural Tanzania: A Preventable Cause of Early Mortality.

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01 Jan 2015
publication

Modulation of type I interferon-associated viral sensing during acute simian immunodeficiency virus infection in African green monkeys.

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11 Oct 2014
publication

SIV Infection of African Green Monkeys

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01 Sep 2014
publication

Total ankle replacement in patients with haemophilia and virus infections–a safe alternative to ankle arthrodesis?

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01 Jul 2014
publication

Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection.

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01 Jun 2014
publication

MHC polymorphism in Caribbean African green monkeys.

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01 Jan 2014
publication

Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?

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01 Sep 2013
publication

Patients’ satisfaction with sexual and reproductive health services delivered in HIV clinics across European regions.

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01 Jul 2013
publication

HIV-associated chronic immune activation.

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13 Sep 2012
publication

Pivotal role of M-DC8⁺ monocytes from viremic HIV-infected patients in TNFα overproduction in response to microbial products.

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01 Sep 2012
publication

Effect of alendronate on HIV-associated osteoporosis: a randomized, double-blind, placebo-controlled, 96-week trial (ANRS 120).

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22 Jun 2012
publication

Expression sequence tag library derived from peripheral blood mononuclear cells of the chlorocebus sabaeus.

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19 Jun 2012
publication

Innate immunity in the control of HIV/AIDS: recent advances and open questions.

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14 Jan 2012
publication

Level of double negative T cells, which produce TGF-β and IL-10, predicts CD8 T-cell activation in primary HIV-1 infection.

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01 Jan 2012
publication

Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection.

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01 Jan 2012
publication

The biased nucleotide composition of HIV-1 triggers type I interferon response and correlates with subtype D increased pathogenicity.

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01 Jan 2012
publication

Systems biology of natural simian immunodeficiency virus infections.

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01 Sep 2011
publication

Greater diversity of HIV DNA variants in the rectum compared to variants in the blood in patients without HAART.

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01 Aug 2011
publication

Sexual protection behavior in HIV-positive gay men: testing a modified information-motivation-behavioral skills model.

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01 Aug 2010
publication

Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques.

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01 May 2010
publication

[Protection against AIDS? The example of African monkeys].

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15 Jan 2010
publication

AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection.

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15 Dec 2009
publication

[Burden of disease and level of patient’s medical care in substitution treatment for opiates].

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01 Dec 2009
publication

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response.

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01 Aug 2009
publication

Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts.

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01 Mar 2009
publication

Gag p27-specific B- and T-cell responses in Simian immunodeficiency virus SIVagm-infected African green monkeys.

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01 Jan 2009
publication

African non human primates infected by SIV – why don’t they get sick? Lessons from studies on the early phase of non-pathogenic SIV infection.

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01 Jun 2008
publication

Effect of SIVmac infection on plasmacytoid and CD1c+ myeloid dendritic cells in cynomolgus macaques.

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01 Jun 2008
publication

Plasmacytoid dendritic cell dynamics and alpha interferon production during Simian immunodeficiency virus infection with a nonpathogenic outcome.

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01 Feb 2008
publication

Early divergence in lymphoid tissue apoptosis between pathogenic and nonpathogenic simian immunodeficiency virus infections of nonhuman primates.

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01 Dec 2007
publication

Nef-mediated enhancement of virion infectivity and stimulation of viral replication are fundamental properties of primate lentiviruses.

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31 Oct 2007
publication

T regulatory cells: aid or hindrance in the clearance of disease?

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01 Oct 2007
publication

Long oligonucleotide microarrays for African green monkey gene expression profile analysis.

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26 Jun 2006
publication

Distinct expression profiles of TGF-beta1 signaling mediators in pathogenic SIVmac and non-pathogenic SIVagm infections.

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16 Jun 2006
publication

Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.

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01 May 2006
publication

Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts.

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20 Jan 2006
publication

Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes.

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01 Oct 2005
publication

Role for plasmacytoid dendritic cells in anti-HIV innate immunity.

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01 Aug 2005
publication

Apoptosis in SIV infection.

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01 May 2005
publication

Impact of viral factors on very early in vivo replication profiles in simian immunodeficiency virus SIVagm-infected African green monkeys.

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06 Apr 2005
publication

First Dominique Dormont International Conference on “Host-pathogen interactions in chronic infections – viral and host determinants of HCV, HCMV, and HIV infections”.

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01 Apr 2005
publication

Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS.

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01 Jan 2005
publication

Simian immunodeficiency virus infection in wild-caught chimpanzees from cameroon.

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02 Jul 2004
publication

Phylogenetic characteristics of three new HIV-1 N strains and implications for the origin of group N.

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01 Jul 2004
publication

Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.

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01 Apr 2004
publication

[Evolution and virulence of primate lentiviruses].

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01 Apr 2004
publication

Viral load in tissues during the early and chronic phase of non-pathogenic SIVagm infection.

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01 Jan 2004
publication

DC-SIGN from African green monkeys is expressed in lymph nodes and mediates infection in trans of simian immunodeficiency virus SIVagm.

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05 Dec 2003
publication

High levels of SIVmnd-1 replication in chronically infected Mandrillus sphinx.

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01 Sep 2003
publication

SIVagm: genetic and biological features associated with replication.

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01 Jul 2003
publication

Broad spectrum of coreceptor usage and rapid disease progression in HIV-1-infected individuals from Central African Republic.

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01 Oct 2002
publication

High levels of viral replication contrast with only transient changes in CD4(+) and CD8(+) cell numbers during the early phase of experimental infection with simian immunodeficiency virus SIVmnd-1 in Mandrillus sphinx.

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01 Jul 2002
publication

Basic research: what is it good for AIDS epidemiology and control?. An e-debate.

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01 May 2002
publication

Quels sont les récepteurs plaquettaires du collagène ?

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01 Sep 2001
publication

Frequent substitution polymorphisms in African green monkey CCR5 cluster at critical sites for infections by simian immunodeficiency virus SIVagm, implying ancient virus-host coevolution.

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01 Aug 2001
publication

Wild Mandrillus sphinx are carriers of two types of lentivirus.

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01 Jul 2001
publication

Synthetic peptide strategy for the detection of and discrimination among highly divergent primate lentiviruses.

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10 Nov 2000
publication

HIV-1 group N among HIV-1-seropositive individuals in Cameroon.

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01 Aug 2000
publication

SIVcpz from a naturally infected Cameroonian chimpanzee: biological and genetic comparison with HIV-1 N.

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01 Aug 2000
publication

High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys.

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01 Jan 2000
publication

env sequences of simian immunodeficiency viruses from chimpanzees in Cameroon are strongly related to those of human immunodeficiency virus group N from the same geographic area.

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13 Nov 1999
publication

Towards improvements in molecular tools for diagnosis and management of HIV infections.

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01 Jul 1999
publication

Mutations in CCR5-coding sequences are not associated with SIV carrier status in African nonhuman primates.

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01 Jun 1999
publication

Increase of HIV-1 subtype A in Central African Republic.

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15 Apr 1999
publication

Predominance of CCR5-dependent HIV-1 subtype E isolates in Cambodia.

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01 Nov 1998
publication

Introduction of HIV-1 subtype A in the French West Indies.

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01 Sep 1998
publication

Identification of a new human immunodeficiency virus type 1 distinct from group M and group O.

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01 Jul 1998
publication

Genetically related human immunodeficiency virus type 1 in three adults of a family with no identified risk factor for intrafamilial transmission.

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10 Jun 1998
publication

Phylogenetic analysis of SIV and STLV type I in mandrills (Mandrillus sphinx): indications that intracolony transmissions are predominantly the result of male-to-male aggressive contacts.

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01 Jun 1997
publication

Relation between phylogeny of African green monkey CD4 genes and their respective simian immunodeficiency virus genes.

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01 Sep 1996
publication

The evolutionary rate of nonpathogenic simian immunodeficiency virus (SIVagm) is in agreement with a rapid and continuous replication in vivo.

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01 May 1996
publication

HIV type 1 Thai subtype E is predominant in South Vietnam.

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15 Jun 1994
publication

Mosaic genome structure of simian immunodeficiency virus from west African green monkeys.

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01 Jan 1994
publication

Seroepidemiologic, molecular, and phylogenetic analyses of simian T-cell leukemia viruses (STLV-I) from various naturally infected monkey species from central and western Africa.

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01 Mar 1993
publication

Simian immunodeficiency viruses from central and western Africa: evidence for a new species-specific lentivirus in tantalus monkeys

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