Timeline
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Philippe Herbomel
Head of Structure
01 Mar 2023
publication
Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis.
Read more01 Oct 2022
publication
A dual involvement of Protocadherin 18a in stromal cell development guides the formation of a functional hematopoietic niche.
Read more02 Sep 2022
publication
Trim33 conditions the lifespan of primitive macrophages and onset of definitive macrophage production.
Read more24 Sep 2020
publication
The cationic amino acid exporter Slc7a7 is induced and vital in tissue macrophages with sustained efferocytic activity.
Read more30 Aug 2019
publication
Coronin 1A depletion restores the nuclear stability and viability of Aip1/Wdr1-deficient neutrophils
Read more20 May 2019
14 Feb 2019
publication
Ultraspecific live imaging of the dynamics of zebrafish neutrophil granules by a histopermeable fluorogenic benzochalcone probe
Read more07 Feb 2019
22 Aug 2018
publication
Anisotropic organization of circumferential actomyosin characterizes hematopoietic stem cells emergence in the zebrafish.
Read more24 May 2018
publication
A Model of Superinfection of Virus-Infected Zebrafish Larvae: Increased Susceptibility to Bacteria Associated With Neutrophil Death
Read more27 Feb 2018
event
Department seminar by Professor David Traver, University of California San Diego: “Developmental regulation of hematopoietic stem cells”
Read more19 Jul 2017
publication
Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues
Read more01 Jul 2017
publication
Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes.
Read more07 Oct 2016
news
SEMINAR ” Cellular and developmental mechanisms controlling germ cell migration in zebrafish “
Read more04 Oct 2016
23 Sep 2016
02 Jun 2016
publication
Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness
Read more01 Oct 2015
28 Sep 2015
publication
NACA deficiency reveals the crucial role of somite-derived stromal cells in haematopoietic niche formation
Read more17 Jul 2015
17 Jul 2015
project
Developmental hematopoiesis, from stem cells emergence to tissue resident leukocytes
Read more08 Jun 2015
28 Mar 2014
publication
Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.
Read more06 Nov 2013
publication
Zebrafish midbrain slow-amplifying progenitors exhibit high levels of transcripts for nucleotide and ribosome biogenesis
Read more11 Oct 2013
publication
Pivotal role of Pten in the balance between proliferation and differentiation of hematopoietic stem cells in zebrafish
Read more05 Sep 2013
publication
The zebrafish as a new model for the in vivo study of Shigella flexneri interaction with phagocytes and bacterial autophagy
Read more05 Sep 2013
publication
Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish.
Read more08 Mar 2013
publication
Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish
Read more03 Feb 2013
01 Jan 2013
publication
Bcl-wav and the mitochondrial calcium uniporter drive gastrula morphogenesis in zebrafish
Read more06 Dec 2012
publication
Inflammatory chemokines direct and restrict leukocyte migration within live tissues as glycan-bound gradients
Read more26 Jul 2012
publication
A new zebrafish model of oro-intestinal pathogen colonization reveals a key role for adhesion in protection by probiotic bacteria
Read more01 Feb 2012
10 Nov 2011
publication
Studying cell behavior in whole zebrafish embryos by confocal live imaging: application to hematopoietic stem cells
Read more15 Sep 2011
publication
Strategies of professional phagocytes in vivo: unlike macrophages, neutrophils engulf only surface-associated microbes.
Read more03 Feb 2011
publication
Whole-body analysis of a viral infection: vascular endothelium is a primary target of infectious hematopoietic necrosis virus in zebrafish larvae.
Read more03 Nov 2010
14 Feb 2010
publication
Blood stem cells emerge from aortic endothelium by a novel type of cell transition
Read more01 Sep 2009
publication
Real-time observation of listeria monocytogenes-phagocyte interactions in living zebrafish larvae.
Read more28 Aug 2009
publication
The two groups of zebrafish virus-induced interferons signal via distinct receptors with specific and shared chains
Read more05 Feb 2009
publication
A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish
Read more01 Jan 2008
12 Oct 2007
publication
Live imaging of emerging hematopoietic stem cells and early thymus colonization
Read more17 Sep 2007
01 Aug 2007
publication
[The zebrafish reveals the odyssey of hematopoietic precursors in developing vertebrate embryos]
Read more31 May 2007
publication
Imaging of nitric oxide in a living vertebrate using a diamino-fluorescein probe
Read more01 Apr 2007
publication
Identification of the zebrafish IFN receptor: implications for the origin of the vertebrate IFN system
Read more07 Dec 2006
publication
Tracing hematopoietic precursor migration to successive hematopoietic organs during zebrafish development.
Read more01 Jun 2005
publication
Otolith matrix proteins OMP-1 and Otolin-1 are necessary for normal otolith growth and their correct anchoring onto the sensory maculae
Read more01 Jan 2005
publication
Imaging early macrophage differentiation, migration, and behaviors in live zebrafish embryos
Read more01 Apr 2004
07 Jan 2004
publication
Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations
Read more01 Jan 2003
01 Dec 2002
publication
Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos
Read more15 Oct 2001
publication
Zebrafish early macrophages colonize cephalic mesenchyme and developing brain, retina, and epidermis through a M-CSF receptor-dependent invasive process
Read more01 Sep 1999
01 Sep 1999
01 Sep 1993
publication
Processing of linear elements in stereopsis: effects of positional and orientational distinctiveness
Read more01 Dec 1990
publication
Synergistic activation of eukaryotic transcription: the multiacceptor target hypothesis
Read more01 Nov 1990
publication
From gene to chromosome: organization levels defined by the interplay of transcription and replication in vertebrates
Read more01 Apr 1990
01 Nov 1989
publication
The rat albumin promoter is composed of six distinct positive elements within 130 nucleotides
Read more01 Jun 1989
publication
Control elements situated downstream of the major transcriptional start site are sufficient for highly efficient polyomavirus late transcription
Read more14 Aug 1987
01 Jul 1987
publication
Determinants of rat albumin promoter tissue specificity analyzed by an improved transient expression system
Read more01 Dec 1984
publication
Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma
Read more01 Nov 1984
publication
Tissue-specific expression is conferred by a sequence from the 5′ end of the rat albumin gene
Read more01 Jan 1983
01 Sep 1982
publication
Physical and biological features of polyoma virus mutants able to infect embryonal carcinoma cell lines
Read more01 Sep 1981
publication
Fine structure of the origin-proximal DNAase I-hypersensitive region in wild-type and EC mutant polyoma
Read more24 Nov 1980
publication