Ligne de temps

Philippe Herbomel
Responsable de Structure
01 mars 2023
publication

Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis.

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01 oct. 2022
publication

A dual involvement of Protocadherin 18a in stromal cell development guides the formation of a functional hematopoietic niche.

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02 sept. 2022
publication

Trim33 conditions the lifespan of primitive macrophages and onset of definitive macrophage production.

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24 sept. 2020
publication

The cationic amino acid exporter Slc7a7 is induced and vital in tissue macrophages with sustained efferocytic activity.

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30 août 2019
publication

Coronin 1A depletion restores the nuclear stability and viability of Aip1/Wdr1-deficient neutrophils

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20 mai 2019
publication

Resident Macrophage Lookalikes of Unexpected Origin

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14 févr. 2019
publication

Ultraspecific live imaging of the dynamics of zebrafish neutrophil granules by a histopermeable fluorogenic benzochalcone probe

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07 févr. 2019
publication

Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo

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22 août 2018
publication

Anisotropic organization of circumferential actomyosin characterizes hematopoietic stem cells emergence in the zebrafish.

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24 mai 2018
publication

A Model of Superinfection of Virus-Infected Zebrafish Larvae: Increased Susceptibility to Bacteria Associated With Neutrophil Death

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27 févr. 2018
event

Department seminar by Professor David Traver, University of California San Diego: “Developmental regulation of hematopoietic stem cells”

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19 juil. 2017
publication

Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues

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01 juil. 2017
publication

Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes.

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07 oct. 2016
news

SEMINAR ” Cellular and developmental mechanisms controlling germ cell migration in zebrafish “

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04 oct. 2016
news

SEMINAR “Decoding blood vessels homeostasis : ros signaling, hemodynamics and more”

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23 sept. 2016
news

SEMINAR ” Life and Near Death Experiences at the Cellular Level “

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02 juin 2016
publication

Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness

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01 oct. 2015
news

SEMINAR “Mechanisms of macrophage tissue infiltration”

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28 sept. 2015
publication

NACA deficiency reveals the crucial role of somite-derived stromal cells in haematopoietic niche formation

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17 juil. 2015
tool

Zebrafish facility

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17 juil. 2015
project

Developmental hematopoiesis, from stem cells emergence to tissue resident leukocytes

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08 juin 2015
project

Behaviour of macrophages and neutrophils in vivo

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28 mars 2014
publication

Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.

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06 nov. 2013
publication

Zebrafish midbrain slow-amplifying progenitors exhibit high levels of transcripts for nucleotide and ribosome biogenesis

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11 oct. 2013
publication

Pivotal role of Pten in the balance between proliferation and differentiation of hematopoietic stem cells in zebrafish

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05 sept. 2013
publication

The zebrafish as a new model for the in vivo study of Shigella flexneri interaction with phagocytes and bacterial autophagy

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05 sept. 2013
publication

Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish.

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08 mars 2013
publication

Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish

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03 févr. 2013
publication

Generating parabiotic zebrafish embryos for cell migration and homing studies

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01 janv. 2013
publication

Bcl-wav and the mitochondrial calcium uniporter drive gastrula morphogenesis in zebrafish

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06 déc. 2012
publication

Inflammatory chemokines direct and restrict leukocyte migration within live tissues as glycan-bound gradients

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26 juil. 2012
publication

A new zebrafish model of oro-intestinal pathogen colonization reveals a key role for adhesion in protection by probiotic bacteria

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01 févr. 2012
publication

Infection-induced hematopoiesis: a zebrafish perspective

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10 nov. 2011
publication

Studying cell behavior in whole zebrafish embryos by confocal live imaging: application to hematopoietic stem cells

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15 sept. 2011
publication

Strategies of professional phagocytes in vivo: unlike macrophages, neutrophils engulf only surface-associated microbes.

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03 févr. 2011
publication

Whole-body analysis of a viral infection: vascular endothelium is a primary target of infectious hematopoietic necrosis virus in zebrafish larvae.

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03 nov. 2010
publication

In vivo analysis of Ifn-γ1 and Ifn-γ2 signaling in zebrafish

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14 févr. 2010
publication

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

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01 sept. 2009
publication

Real-time observation of listeria monocytogenes-phagocyte interactions in living zebrafish larvae.

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28 août 2009
publication

The two groups of zebrafish virus-induced interferons signal via distinct receptors with specific and shared chains

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05 févr. 2009
publication

A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish

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01 janv. 2008
publication

In vivo analysis of zebrafish innate immunity

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12 oct. 2007
publication

Live imaging of emerging hematopoietic stem cells and early thymus colonization

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17 sept. 2007
publication

Origins and unconventional behavior of neutrophils in developing zebrafish.

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01 août 2007
publication

[The zebrafish reveals the odyssey of hematopoietic precursors in developing vertebrate embryos]

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31 mai 2007
publication

Imaging of nitric oxide in a living vertebrate using a diamino-fluorescein probe

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01 avr. 2007
publication

Identification of the zebrafish IFN receptor: implications for the origin of the vertebrate IFN system

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07 déc. 2006
publication

Tracing hematopoietic precursor migration to successive hematopoietic organs during zebrafish development.

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01 juin 2005
publication

Otolith matrix proteins OMP-1 and Otolin-1 are necessary for normal otolith growth and their correct anchoring onto the sensory maculae

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01 janv. 2005
publication

Imaging early macrophage differentiation, migration, and behaviors in live zebrafish embryos

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01 avr. 2004
publication

Focusing light on infection in four dimensions

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07 janv. 2004
publication

Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations

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01 janv. 2003
publication

The zebrafish as a model organism to study development of the immune system

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01 déc. 2002
publication

Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos

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15 oct. 2001
publication

Zebrafish early macrophages colonize cephalic mesenchyme and developing brain, retina, and epidermis through a M-CSF receptor-dependent invasive process

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01 sept. 1999
publication

Spinning nuclei in the brain of the zebrafish embryo

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01 sept. 1999
publication

Ontogeny and behaviour of early macrophages in the zebrafish embryo

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01 sept. 1993
publication

Processing of linear elements in stereopsis: effects of positional and orientational distinctiveness

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01 déc. 1990
publication

Synergistic activation of eukaryotic transcription: the multiacceptor target hypothesis

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01 nov. 1990
publication

From gene to chromosome: organization levels defined by the interplay of transcription and replication in vertebrates

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01 avr. 1990
publication

Anatomy of the rat albumin promoter

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01 nov. 1989
publication

The rat albumin promoter is composed of six distinct positive elements within 130 nucleotides

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01 juin 1989
publication

Control elements situated downstream of the major transcriptional start site are sufficient for highly efficient polyomavirus late transcription

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14 août 1987
publication

Factors involved in control of tissue-specific expression of albumin gene

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01 juil. 1987
publication

Determinants of rat albumin promoter tissue specificity analyzed by an improved transient expression system

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01 déc. 1984
publication

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

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01 nov. 1984
publication

Tissue-specific expression is conferred by a sequence from the 5′ end of the rat albumin gene

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01 janv. 1983
publication

Structure and function of the promoter-enhancer region of polyoma and SV40

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01 sept. 1982
publication

Physical and biological features of polyoma virus mutants able to infect embryonal carcinoma cell lines

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01 sept. 1981
publication

Fine structure of the origin-proximal DNAase I-hypersensitive region in wild-type and EC mutant polyoma

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24 nov. 1980
publication

[Fidelity of a polymerization reaction according to the proximity to equilibrium]

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