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Members
Groups
Laboratory
Biochemistry of Macromolecular Interactions
Daniel Ladant
Laboratory
Structural Microbiology
Pedro Alzari
Laboratory
Architecture and Dynamics of Biological Macromolecules
Marc Delarue
Laboratory
Structural Bioinformatics
Michael Nilges
Laboratory
Bacterial transmembrane systems
Nadia Izadi-Pruneyre
Laboratory
Bacterial Cell Cycle Mechanisms
Anne Marie Wehenkel
Laboratory
Computational Structural Biology
Max Bonomi
Publications
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2024Dynamic interplay between a TonB-dependent heme transporter and a TonB protein in a membrane environment, mBio, In press, pp.e0178124. ⟨10.1128/mbio.01781-24⟩.
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2024Molecular mechanism of a triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase., iScience 2024 Oct; 27(10): 110967.
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2024Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features, FEBS Journal, In press, ⟨10.1111/febs.17232⟩.
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2024Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN., Nat Commun 2024 Jul; 15(1): 5725.
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2024Structure and Dynamics of Type 4a Pili and Type 2 Secretion System Endopili, In: Macromolecular Protein Complexes V, vol 104. Chapter 21. p549-563.
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2024A comprehensive dataset of protein-protein interactions and ligand binding pockets for advancing drug discovery, Scientific Data , 2024, 11 (1), pp.402. ⟨10.1038/s41597-024-03233-z⟩.
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2024Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1., Eur J Med Chem 2024 Apr; 269(): 116308.
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2024Mechanism of action of phthalazinone derivatives against rabies virus., Antiviral Res 2024 Apr; 224(): 105838.
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2024Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms, Nature Communications, 2024, 15 (1), pp.2414. ⟨10.1038/s41467-024-46677-y⟩.
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2024Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress., mBio 2024 Mar; 15(3): e0019824.
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