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  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
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  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
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Scientific Fields
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Courses

09:00
11
Jan 2021
Course

Biochimie des Protéines

La biochimie des protéines est une discipline sans cesse dynamisée par l’émergence de nouvelles technologies à la convergence de la chimie, la biophysique, la biologie moléculaire et la biologie cellulaire. Elle regroupe les méthodes […]
Institut Pasteur
Célia Caillet-Saguy
Thierry Rose
Nicolas Wolff
2021-01-11 09:00:00 2021-02-12 18:00:00 Europe/Paris Biochimie des Protéines La biochimie des protéines est une discipline sans cesse dynamisée par l’émergence de nouvelles technologies à la convergence de la chimie, la biophysique, la biologie moléculaire et la biologie cellulaire. Elle regroupe les méthodes […] 28 Rue du Docteur Roux, Paris, France

Projects

Project
Ongoing
3 Members

Identification of cellular PDZ-containing Proteins targeted by the virus SARS-Cov-2 during infection (PPCOVi)

Nicolas Wolff (PI)

Thanks to their binding to PDZ domains, viral proteins play an important role in the replication and pathogenesis of SARS-CoV. Through cellular and in vitro high-throughput tests, this project aims to identify the cellular […]
Project
Ongoing
5 Members

Mutations in PDZ Binding Motif (PBM)-containing proteins associated to the Usher syndrome

Nicolas Wolff (PI)

Mutations in PDZ Binding Motif (PBM)-containing proteins are also associated to the Usher syndrome, a genetic disease resulting in both hearing loss and visual impairment. Most Usher proteins are present in auditory hair cells […]
Project
Ongoing
4 Members

Rabies virus neuronal infection

Nicolas Wolff (PI)

We have shown that proteins from Rabies virus during infection disrupts the interactions of the kinase MAST2 and phosphatase PTPN4 (PDZ domain) with their respective PDZ Binding Motif (PBM)-containing cellular ligands, the phosphatase PTEN […]
Project
Ongoing
6 Members

Role of PDZ-binding motif from Flavivirus non-structural proteins in flaviviral life cycle

Nathalie Pardigon (PI)

Arthropod-borne viruses (arboviruses) include numerous human and animal pathogens that are important global health threats. Flaviviruses are arboviruses belonging to the Flaviviridae family. They include neurotropic viruses such as West Nile (WNV), Japanese encephalitis […]

Publications

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