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  • Deputy Director of National Reference Center
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  • Director of Center
  • Director of Department
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About

I did my Master and my PhD in the NMR unit of Biomolecules headed by Mrs. Delepierre at the Institut Pasteur. My thesis focused on the study of heme acquisition mechanism in bacteria. I used biophysical approaches, mainly nuclear magnetic resonance (NMR). I joined for my post-doc the team of biocrystallography led by Stéphane Bressanelli in the Molecular and Structural Virology Unit directed by Yves Gaudin (Gif-sur-Yvette). My project focused on the study of genome replication of hepatitis C virus (HCV). I acquired a dual expertise in NMR and X-ray crystallography. Then I joined the team of Nicolas Wolff. I worked mainly on the human phosphatases PTPN4 and PTPN3. More generally, I am interested in the signaling pathways of the cell involving PDZ-containing proteins.
Our group joined the Channel Receptors Unit since 2018 led by Pierre-Jean Corringer (Department of Neuroscience). The Unit is interested by the pentameric ligand-gated ion channels (pLGICs). This superfamily of membrane proteins are involved in particular in the neuronal communication.

Projects

CV

I did my Master and my PhD in the NMR unit of Biomolecules headed by Mrs. Delepierre at the Institut Pasteur. My thesis focused on the study of heme acquisition mechanism in bacteria. I used biophysical approaches, mainly nuclear magnetic resonance (NMR). I joined for my post-doc the team of biocrystallography led by Stéphane Bressanelli in the Molecular and Structural Virology Unit directed by Yves Gaudin (Gif-sur-Yvette). My project focused on the study of genome replication of hepatitis C virus (HCV). I acquired a dual expertise in NMR and X-ray crystallography. Then I joined the team of Nicolas Wolff. I worked mainly on the human phosphatases PTPN4 and PTPN3. More generally, I am interested in the signaling pathways of the cell involving PDZ-containing proteins.
Our group joined the Channel Receptors Unit since 2018 led by Pierre-Jean Corringer (Department of Neuroscience). The Unit is interested by the pentameric ligand-gated ion channels (pLGICs). This superfamily of membrane proteins are involved in particular in the neuronal communication.

Publications

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