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© Institut Pasteur
Structure cristalline de l'hémophore HasA de Serratia marcescens. Les hélices alpha sont colorées en rouge et les brins bêta en bleu. La molécule d'héme est colorée en jaune et les chaînes latérales des acides aminés ligands de l'hème sont colorées en vert.

Projects

CV

I did my Master and my PhD in the NMR unit of Biomolecules headed by Mrs. Delepierre at the Institut Pasteur. My thesis focused on the study of heme acquisition mechanism in bacteria. I used biophysical approaches, mainly nuclear magnetic resonance (NMR).

I joined for my post-doc the team of biocrystallography led by Stéphane Bressanelli in the Molecular and Structural Virology Unit directed by Yves Gaudin (Gif-sur-Yvette). My project focused on the study of genome replication of hepatitis C (HCV). I acquired a dual expertise in NMR and X-ray crystallography.

Then I joined the team of Nicolas Wolff in the NMR unit of Biomolecules. I worked mainly on the functional and structural characterization of the human phosphatase PTPN4 until my integration in 2014. I develop a new project within the group on the anti-proliferative human phosphatase PTPN3. I am also involved in a project with Nicolas Wolff on viral hijacking of PDZ proteins among flaviviruses. More generally, I am interested in disturbance by viruses of the signaling pathways of the infected cell involving PDZ domains.

Publications