Timeline
François Schweisguth
Head of Structure
13 Mar 2024
01 Dec 2022
15 May 2021
publication
A combination of Notch signaling, preferential adhesion and endocytosis induces a slow mode of cell intercalation in the Drosophila retina.
Read more25 Mar 2021
19 Nov 2020
event
DSCB Department seminar: Yohanns Bellaïche, Institut Curie – “How does morphogenesis cope with cell and tissue size?”
Read more02 Nov 2020
publication
Tissue-wide coordination of epithelium-to-neural stem cell transition in the Drosophila optic lobe requires Neuralized.
Read more31 Jan 2020
event
!!! CANCELLED !!! François Jacob & Jacques Monod Anniversary Symposium – Friday, June 19th, 2020 – Institut Pasteur, Paris
Read more31 Oct 2019
publication
Optogenetic inhibition of Delta reveals digital Notch signalling output during tissue differentiation
Read more02 Aug 2019
publication
Regulation of Notch output dynamics via specific E(spl)-HLH factors during bristle patterning in Drosophila
Read more02 Jul 2019
publication
Activation of Arp2/3 by WASp Is Essential for the Endocytosis of Delta Only during Cytokinesis in Drosophila
Read more11 Jun 2019
event
Developmental and Stem Cell Biology Departement seminar: Olivier Pourquié, Harvard Stem Cell Institute, Boston, USA
Read more03 Jun 2019
20 May 2019
publication
Stem Cell Proliferation Is Kept in Check by the Chromatin Regulators Kismet/CHD7/CHD8 and Trr/MLL3/4
Read more01 Feb 2019
23 Nov 2018
event
DSCB and C3BI Departments Seminar by Professor Stein Aerts, Department of Human Genetics, Laboratory of Computational Biology, KU Leuven
Read more19 Nov 2018
23 Oct 2018
event
Developmental and Stem Cell Biology Department seminar by Doctor Abderrahman Khila, Developmental Genomics and Evolution team, Institut de Génomique Fonctionnelle de Lyon
Read more23 May 2018
event
BDCS Department seminar by Professor Norbert Perrimon, Harvard Medical School, Boston, USA
Read more17 Nov 2017
publication
Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila
Read more03 Nov 2017
publication
Regulation of cortical stability by RhoGEF3 in mitotic sensory organ precursor cells in Drosophila
Read more21 Sep 2017
publication
Cell Polarity and Notch Signaling: Linked by the E3 Ubiquitin Ligase Neuralized?
Read more20 Jul 2017
publication
Intra-lineage Fate Decisions Involve Activation of Notch Receptors Basal to the Midbody in Drosophila Sensory Organ Precursor Cells
Read more10 Apr 2017
publication
Neuralized regulates Crumbs endocytosis and epithelium morphogenesis via specific Stardust isoforms
Read more06 Apr 2017
publication
Self-organized Notch dynamics generate stereotyped sensory organ patterns in Drosophila
Read more31 Mar 2017
15 Feb 2017
23 Jan 2017
publication
Response to “Does pupal communication influence Wolbachia-mediated cytoplasmic incompatibility?”
Read more09 Jan 2017
12 Apr 2016
publication
Control of Neural Daughter Cell Proliferation by Multi-level Notch/Su(H)/E(spl)-HLH Signaling
Read more21 Sep 2015
publication
A Wolbachia-Sensitive Communication between Male and Female Pupae Controls Gamete Compatibility in Drosophila
Read more10 Jul 2015
07 Jun 2015
11 May 2015
07 May 2015
30 Apr 2015
02 Apr 2015
publication
Planar Cell Polarity Breaks the Symmetry of PAR Protein Distribution prior to Mitosis in Drosophila Sensory Organ Precursor Cells
Read more01 Mar 2015
23 Jan 2015
publication
Asymmetric cell division in the Drosophila bristle lineage: from the polarization of sensory organ precursor cells to Notch-mediated binary fate decision
Read more03 Nov 2014
publication
A fluorescent tagging approach in Drosophila reveals late endosomal trafficking of Notch and Sanpodo
Read more15 Sep 2014
05 Jun 2014
25 Mar 2014
publication
Imogene: identification of motifs and cis-regulatory modules underlying gene co-regulation
Read more01 Jan 2014
publication
Antibody uptake assay and in vivo imaging to study intracellular trafficking of Notch and Delta in Drosophila
Read more12 Aug 2013
publication
Aurora B and cyclin B have opposite effects on the timing of cytokinesis abscission in Drosophila germ cells and in vertebrate somatic cells
Read more10 May 2013
21 Mar 2013
publication
Numb localizes at endosomes and controls the endosomal sorting of notch after asymmetric division in Drosophila
Read more22 Oct 2012
publication
TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals
Read more08 Oct 2012
publication
Functional analysis of the NHR2 domain indicates that oligomerization of Neuralized regulates ubiquitination and endocytosis of Delta during Notch signaling
Read more15 Apr 2012
publication
Regulation of epithelial polarity by the E3 ubiquitin ligase Neuralized and the Bearded inhibitors in Drosophila
Read more22 Jan 2012
28 Oct 2011
publication
Glycosphingolipids in signaling and development: from liposomes to model organisms
Read more28 Sep 2011
publication
Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine
Read more11 Jan 2011
29 Jul 2010
publication
Genome-wide identification of cis-regulatory motifs and modules underlying gene coregulation using statistics and phylogeny
Read more21 Apr 2010
01 Mar 2010
22 Feb 2010
publication
Notch ligand activity is modulated by glycosphingolipid membrane composition in Drosophila melanogaster
Read more25 Aug 2009
15 Jun 2009
publication
Genome engineering-based analysis of Bearded family genes reveals both functional redundancy and a nonessential function in lateral inhibition in Drosophila
Read more01 Mar 2009
13 Feb 2009
publication
Van Gogh and Frizzled act redundantly in the Drosophila sensory organ precursor cell to orient its asymmetric division
Read more27 Aug 2008
publication
Overexpression of partner of numb induces asymmetric distribution of the PI4P 5-Kinase Skittles in mitotic sensory organ precursor cells in Drosophila
Read more01 Jan 2008
publication
Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?
Read more04 Jan 2007
publication
aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb
Read more15 Dec 2006
publication
Transcription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interference
Read more01 Feb 2006
publication
Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila
Read more01 Dec 2005
01 Nov 2005
publication
Drosophila Ric-8 regulates Galphai cortical localization to promote Galphai-dependent planar orientation of the mitotic spindle during asymmetric cell division
Read more24 May 2005
publication
Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and Sanpodo in Drosophila sensory-organ precursor cells
Read more20 May 2005
01 Apr 2005
15 Mar 2005
publication
Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila
Read more04 Aug 2004
publication
Evolution of the larval peripheral nervous system in Drosophila species has involved a change in sensory cell lineage
Read more01 Jun 2004
01 May 2004
publication
Slit-Robo signalling prevents sensory cells from crossing the midline in Drosophila
Read more01 Apr 2004
01 Feb 2004
01 Feb 2004
01 Jan 2004
publication
The planar cell polarity protein Strabismus promotes Pins anterior localization during asymmetric division of sensory organ precursor cells in Drosophila
Read more01 Aug 2003
01 Jul 2003
publication
Unequal segregation of Neuralized biases Notch activation during asymmetric cell division
Read more01 Apr 2003
05 Feb 2003
publication
Snail is required for Delta endocytosis and Notch-dependent activation of single-minded expression
Read more01 Jan 2003
publication
[Cell polarity and asymmetric division in the peripheral nervous system of Drosophila]
Read more01 Oct 2002
publication
Binary cell death decision regulated by unequal partitioning of Numb at mitosis
Read more22 Jan 2002
publication
Drosophila E-cadherin regulates the orientation of asymmetric cell division in the sensory organ lineage
Read more10 Aug 2001
publication
The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila
Read more01 Aug 2001
15 May 2001
publication
Transcriptional repression by suppressor of hairless involves the binding of a hairless-dCtBP complex in Drosophila
Read more01 Mar 2001
publication
Lineage, cell polarity and inscuteable function in the peripheral nervous system of the Drosophila embryo
Read more08 Jan 2001
publication
Wasp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling
Read more01 Jan 2001
publication
Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division
Read more06 Apr 2000
01 Feb 2000
publication
Covalent modification of the transcriptional repressor tramtrack by the ubiquitin-related protein Smt3 in Drosophila flies
Read more01 Feb 2000
publication
Repression by suppressor of hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo
Read more28 Sep 1999
publication
Dominant-negative mutation in the beta2 and beta6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage
Read more01 Aug 1999
publication
Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell
Read more01 Jul 1999
18 Jun 1998
publication
Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos
Read more14 May 1998
publication
Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila
Read more01 Mar 1998
publication
The activity of Drosophila Hairless is required in pupae but not in embryos to inhibit Notch signal transduction
Read more01 Jan 1997
01 Jun 1996
publication
Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling
Read more01 Jan 1996
publication
Control of cell fate choices by lateral signaling in the adult peripheral nervous system of Drosophila melanogaster
Read more01 Nov 1995
publication
The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling
Read more01 Jun 1995
publication
Suppressor of Hairless is required for signal reception during lateral inhibition in the Drosophila pupal notum
Read more01 Jan 1995
publication
Evolutionarily conserved positive and negative cis-acting elements control the blastoderm-specific expression of the Drosophila serendipity alpha cellularisation gene
Read more01 Dec 1994
publication
The sequence similarity of the Drosophila suppressor of hairless protein to the integrase domain has no functional significance in vivo
Read more15 Oct 1994
publication
Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-J kappa, by direct protein-protein interaction with Drosophila hairless
Read more01 Jun 1994
publication
Antagonistic activities of Suppressor of Hairless and Hairless control alternative cell fates in the Drosophila adult epidermis
Read more01 Oct 1993
publication
Relationship between expression of serendipity alpha and cellularisation of the Drosophila embryo as revealed by interspecific transformation
Read more26 Jun 1992
publication
Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates
Read more15 Sep 1991
01 Jan 1991
01 Jun 1990
publication
The serendipity alpha gene encodes a membrane-associated protein required for the cellularization of the Drosophila embryo
Read more01 Nov 1989
publication