Khalil is a research engineer (IE2) at the CNRS. He obtained a PhD in 2004. He joined the team (then at the Ecole Normale Supérieur in Paris) in 2007 and moved with the lab at the Institut Pasteur in 2008. He is a molecular biologist specialist, a cloning expert in BAC recombineering and CRISPR-based genome modifications. As such, Khalil has contributed to most lab projects, notably the ‘Imogene Regulatory Genomics’ and the ‘Cell Biology of Notch’ projects. He is also performing various protein biochemistry experiments.
Cell polarity and asymmetric cell division
Asymmetric Cell Division (ACD) is a simple and conserved mechanism to generate cell diversity during embryogenesis and throughout adult life. In this process, a mother cell divides to generate two daughter cells with distinct […]
Cell biology of Notch
Cell-cell signaling mediated by Notch receptors regulates a wide range of developmental processes and perturbations of Notch signaling activity underlie various human developmental and adult-onset diseases, including T-cell leukemia and other cancers. Additionally, Notch […]
Fate patterning and self-organized Notch dynamics
For many developmental processes, the list of the required elements (genes/molecules) is known but the resulting dynamics is often poorly understood. Thus, in most developmental patterning processes, the relative importance of external positional cues […]