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About

Dr. Christophe d’Enfert is a Professor at Institut Pasteur and the Head of the Fungal Biology and Pathogenicity Unit at Institut Pasteur. Dr. d’Enfert gained his PhD at Institut Pasteur working on protein secretion in Gram-negative bacteria. During his post-doctoral training at the University of California at Berkeley, he studied protein secretion in yeast. Since 1992, he joined Institut Pasteur to study human pathogenic fungi and has developed both fundamental and applied research on two major fungal pathogens, Candida albicans and Aspergillus fumigatus. Current research in his laboratory focuses on the development of tools for functional genomics of C. albicans and the study of C. albicans genome dynamics and diversity, biofilm formation and morphogenesis.
Christophe d’Enfert is also Vice President for Technology and Scientific Program. He joined Institut Pasteur management in March 2018 and is in charge of the running and development of core facilities, large infrastructure programs and the implementation of incentive programs.
Dr. d’Enfert was the Vice-Chair of Institut Pasteur Genomes and Genetics Department from 2009 to 2014 and the founding Chair of Institut Pasteur Department of Mycology from 2014 to 2018. He was also a Visiting Professor at Ecole Polytechnique in France from 2004 to 2016 and Scientific Director of the French Technology Research Institute BIOASTER.

Transversal Projects

Institut Carnot Pasteur MS

The Carnot Label Carnot label is granted to public research structures, showing high level R&I competencies dedicated to fostering innovation with industrial partners. The Carnot Institutes (IC) are funded to conduct upstream research capable […]

LabEx IBEID – Integrative Biology of Emerging Infectious Diseases

Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart, is to develop a structure to anticipate and tackle emerging infectious diseases (EIDs). […]

Projects

project
Ongoing
2 Members

FunHoMic MC-ITN: Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections

Christophe D’Enfert (PI)

FunHoMic is a Marie Curie Innovative Training Network that will train 13 Early Stage Researchers and decipher the fungus-host-microbiota interplay to improve the management of fungal infections. FunHoMIc is coordinated by Christophe d’Enfert at […]
project
Ongoing
8 Members

Candida albicans genomic diversity and its underlying mechanisms

Christophe D’Enfert (PI)

Following our introduction of Multi-Locus Sequence Typing (MLST) as the state-of-the-art methodology for molecular epidemiology studies of C. albicans, the Fungal Biology and Pathogenicity Unit at Institut Pasteur is now progressing into population genomics […]
project
Ongoing
10 Members

Candida albicans colonization of abiotic and biotic surfaces

Christophe D’Enfert (PI)

Biofilms formed by C. albicans on indwelling devices play a major role in the persistence of nosocomial infections, largely because of their elevated tolerance to antifungals. The Fungal Biology and Pathogenicity Unit at Institut […]
project
Ongoing
6 Members

Regulation of Candida albicans morphogenesis

Christophe D’Enfert (PI)

The Fungal Biology and Pathogenicity Unit at Institut Pasteur is interested in the regulation of the yeast-to-hypha transition in C. albicans because of its role in biofilm formation and, more generally, in virulence. While […]
project
Ongoing
4 Members

FunComPath

Christophe D’Enfert (PI)

FunComPath is a network within the Infect-ERA programme (www.infect-era.eu). Infect-ERA is an ERA-Net on human infectious diseases funded under the EU 7th Research Framework Programme (2013 – 2016). It is a continuation of the […]
project
Ongoing
5 Members

CANDIHUB

Christophe D’Enfert (PI)

Candida albicans and Candida glabrata are the two major yeast species responsible for invasive fungal infections in humans. Systemic infections due to C. albicans and C. glabrata are associated with high mortality rates despite […]

Publications

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