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Projects

project
Ongoing
9 Members

Candida albicans genomic diversity and its underlying mechanisms

Christophe D’Enfert (PI)

Following our introduction of Multi-Locus Sequence Typing (MLST) as the state-of-the-art methodology for molecular epidemiology studies of C. albicans, the Fungal Biology and Pathogenicity Unit at Institut Pasteur is now progressing into population genomics […]
project
Ongoing
8 Members

Candida albicans colonization of abiotic and biotic surfaces

Christophe D’Enfert (PI)

Biofilms formed by C. albicans on indwelling devices play a major role in the persistence of nosocomial infections, largely because of their elevated tolerance to antifungals. The Fungal Biology and Pathogenicity Unit at Institut […]
project
Ongoing
6 Members

Regulation of Candida albicans morphogenesis

Christophe D’Enfert (PI)

The Fungal Biology and Pathogenicity Unit at Institut Pasteur is interested in the regulation of the yeast-to-hypha transition in C. albicans because of its role in biofilm formation and, more generally, in virulence. While […]
project
Ongoing
15 Members

AIC Mycology

Christophe D’Enfert (PI)

Fungal infections have emerged over the past three decades as a considerable threat to human health. These deadly fungal infections are almost all due to species from three genera: Aspergillus, Candida and Cryptococcus. The […]
project
Ongoing
4 Members

FunComPath

Christophe D’Enfert (PI)

FunComPath is a network within the Infect-ERA programme (www.infect-era.eu). Infect-ERA is an ERA-Net on human infectious diseases funded under the EU 7th Research Framework Programme (2013 – 2016). It is a continuation of the […]
project
Ongoing
5 Members

CANDIHUB

Christophe D’Enfert (PI)

Candida albicans and Candida glabrata are the two major yeast species responsible for invasive fungal infections in humans. Systemic infections due to C. albicans and C. glabrata are associated with high mortality rates despite […]

CV

Christophe d’Enfert, a Professor at Institut Pasteur, is the Chair of the Mycology Department and the Head of the Fungal Biology and Pathogenicity Unit. Christophe d’Enfert gained his PhD at Institut Pasteur working on protein secretion in Gram-negative bacteria with Prof. Maxime Schwartz and Prof. Anthony Pugsley. During his post-doctoral training at the University of California at Berkeley with Prof. Randy Schekman, he studied protein secretion in yeast. Since 1992, he joined Institut Pasteur to study human pathogenic fungi and has developed both fundamental and applied research on two major fungal pathogens, Candida albicans and Aspergillus fumigatus. Current research in his laboratory focuses on the development of tools for functional genomics of C. albicans and the study of C. albicans genome dynamics and diversity, biofilm formation and morphogenesis.

Publications

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