Dr. Christophe d’Enfert is a Professor at Institut Pasteur and the Head of the Fungal Biology and Pathogenicity Unit at Institut Pasteur. Dr. d’Enfert gained his PhD at Institut Pasteur working on protein secretion in Gram-negative bacteria. During his post-doctoral training at the University of California at Berkeley, he studied protein secretion in yeast. Since 1992, he joined Institut Pasteur to study human pathogenic fungi and has developed both fundamental and applied research on two major fungal pathogens, Candida albicans and Aspergillus fumigatus. Current research in his laboratory focuses on the development of tools for functional genomics of C. albicans and the study of C. albicans genome dynamics and diversity, biofilm formation and morphogenesis.
Christophe d’Enfert is also Scientific Director of Institut Pasteur. He joined Institut Pasteur management in March 2018 as Vice President for Technology and Scientific Programs, in charge of the running and development of core facilities, large infrastructure programs and the implementation of incentive programs. In January 2020, he was appointed Scientific Director of Institut Pasteur, coordinating scientific and medical activities, scientific evaluation and recruitments, access to technology, and teaching.
Dr. d’Enfert was the Vice-Chair of Institut Pasteur Genomes and Genetics Department from 2009 to 2014 and the founding Chair of Institut Pasteur Department of Mycology from 2014 to 2018. He was also a Visiting Professor at Ecole Polytechnique in France from 2004 to 2016 and Scientific Director per interim of the French Technology Research Institute BIOASTER.
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2021Regulators of commensal and pathogenic life-styles of an opportunistic fungus-Candida albicans., Yeast 2021 04; 38(4): 243-250.
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2021ATP released by Candida albicans is associated with reduced skin infectivity., J Invest Dermatol 2021 Mar; (): .
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2021Ethylzingerone, a Novel Compound with Antifungal Activity., Antimicrob Agents Chemother 2021 03; 65(4): .
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2021Factors that influence bidirectional long-tract homozygosis due to double-strand break repair in Candida albicans., Genetics 2021 Mar; (): .
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2021Involvement of amyloid proteins in the formation of biofilms in the pathogenic yeast Candida albicans., Res Microbiol 2021 Jan; (): 103813.
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2020A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans., Nat Commun 2020 12; 11(1): 6224.
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2020The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives., FEMS Microbiol Rev 2020 Nov; (): .
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2020Use of CRISPR-Cas9 To Target Homologous Recombination Limits Transformation-Induced Genomic Changes in Candida albicans., mSphere 2020 09; 5(5): .
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2020Candida albicans and Candida dubliniensis Show Different Trailing Effect Patterns When Exposed to Echinocandins and Azoles., Front Microbiol 2020 ; 11(): 1286.
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2020A SARS-CoV-2 protein interaction map reveals targets for drug repurposing., Nature 2020 07; 583(7816): 459-468.
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