Dr. Christophe d’Enfert is a Professor at Institut Pasteur and the Head of the Fungal Biology and Pathogenicity Unit at Institut Pasteur. Dr. d’Enfert gained his PhD at Institut Pasteur working on protein secretion in Gram-negative bacteria. During his post-doctoral training at the University of California at Berkeley, he studied protein secretion in yeast. Since 1992, he joined Institut Pasteur to study human pathogenic fungi and has developed both fundamental and applied research on two major fungal pathogens, Candida albicans and Aspergillus fumigatus. Current research in his laboratory focuses on the development of tools for functional genomics of C. albicans and the study of C. albicans genome dynamics and diversity, biofilm formation and morphogenesis.
Christophe d’Enfert is also Vice President for Technology and Scientific Program. He joined Institut Pasteur management in March 2018 and is in charge of the running and development of core facilities, large infrastructure programs and the implementation of incentive programs.
Dr. d’Enfert was the Vice-Chair of Institut Pasteur Genomes and Genetics Department from 2009 to 2014 and the founding Chair of Institut Pasteur Department of Mycology from 2014 to 2018. He was also a Visiting Professor at Ecole Polytechnique in France from 2004 to 2016 and Scientific Director of the French Technology Research Institute BIOASTER.
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2020A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans., Nat Commun 2020 12; 11(1): 6224.
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2020The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives., FEMS Microbiol Rev 2020 Nov; (): .
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2019Biofilms Are Generally Devoid of Persister Cells, Antimicrob. Agents Chemother. 2019 May;63(5).
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2019Studying fungal pathogens of humans and fungal infections: fungal diversity and diversity of approaches, Genes Immun. 2019 05;20(5):403-414.
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2019One step ahead: Innovation in core facilities, EMBO Rep. 2019 Apr;20(4).
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2019Candida albicans: An Emerging Yeast Model to Study Eukaryotic Genome Plasticity, Trends Genet. 2019 Apr;35(4):292-307.
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2019Within-Host Genomic Diversity of Candida albicans in Healthy Carriers, Sci Rep 2019 Feb;9(1):2563.
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2019Identification of Recessive Lethal Alleles in the Diploid Genome of a Candida albicans Laboratory Strain Unveils a Potential Role of Repetitive Sequences in Buffering Their Deleterious Impact, mSphere 2019 02;4(1).
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2019From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis., Curr Top Microbiol Immunol 2019 ; 422(): 61-99.
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2018Evolving a pathogen to be protective, Science 2018 Nov;362(6414):523-524.
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