Javier Pizarro-Cerda obtained B.Sc. and M.Sc. degrees from the University of Costa Rica while working in the laboratory of Edgardo Moreno, studying the adaptations of the outer membrane of the Gram-negative pathogen Brucella abortus to cationic peptides. He then obtained a D.E.A. and a Ph.D. from the University of Aix-Marseilles while working in the laboratory of Jean-Pierre Gorvel, identifying the intracellular trafficking of Brucella abortus in epithelial cells. Subsequently, he joined the laboratory of Pascale Cossart at the Pasteur Institute in Paris to investigate signaling cascades triggered by the Gram-positive pathogen Listeria monocytogenes during invasion of host mammalian cells. In 2002 Javier Pizarro-Cerda joins the Pasteur Institute as a permanent researcher and obtains his first grant from the French Ministry of Research. Since, he has been involved in local (Pasteur Institute Transversal Programs), national (French National Agency for Research, Defense Innovation Agency) and international (ERANET, Systems X, National Institutes of Health) research initiatives, investigating the adaptations of bacterial pathogens to intracellular life. He has been actively involved in teaching and has participated in practical and theoretical courses in France, Argentina, Costa Rica, Grèce and China. During his career, Javier Pizarro-Cerda has developed his research as invited investigator in different international laboratories including the Center for Microscopy & Microanalysis (Queensland University, Australia), the Weizmann Institute (Rehovot, Israel), the University of Texas-Southwestern Medical Center (Dallas, USA), the Max Planck Institute for Infection Biology (Berlin, Germany) and the Biozentrum (Basel, Switzerland). In 1998, Javier Pizarro-Cerda obtains the Costarrican National Award for Science ‘Clodomiro Picado-Twight’, in 2012 he becomes member of the Costarrican Academy of Sciences and in 2015 he receives the High Chamber Medal from the French Senate for his contribution fostering interactions between France and Latin America. In 2016, Javier Pizarro-Cerda becomes head of the ‘Systems Biology of Bacterial Infections’ Group and is promoted as Research Director at the Pasteur Institute. In 2017 he receives the ‘Canetti Prize’ from the Pasteur Institute Scientific Council for his global contributions to the field of infectious diseases and becomes head of the Yersinia Research Unit as well as Director of the World Health Organization (WHO) Collaborating Reference and Research Centre for Yersinia. In 2018 he becomes member of the WHO International Roster of Experts (Plague Panel) while in 2019 Javier Pizarro-Cerda is admited as member of the Academia Europaea. In 2022 Javier Pizarro-Cerda becomes deputy director of the National Reference Laboratory ‘Plague and Other Yersinioses’.
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2023Yersiniomics, a Multi-Omics Interactive Database for Yersinia Species., Microbiol Spectr 2023 Feb; (): e0382622.
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2022Evolution of immune genes is associated with the Black Death., Nature 2022 Nov; 611(7935): 312-319.
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2022Analytical framework to evaluate and optimize the use of imperfect diagnostics to inform outbreak response: Application to the 2017 plague epidemic in Madagascar., PLoS Biol 2022 Aug; 20(8): e3001736.
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2022First Description of a Yersinia pseudotuberculosis Clonal Outbreak in France, Confirmed Using a New Core Genome Multilocus Sequence Typing Method., Microbiol Spectr 2022 Jul; (): e0114522.
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2022NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes., Elife 2022 Jun; 11(): .
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2022Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination and diagnostics., Microbes Infect 2019 ; 21(5-6): 202-212.
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2021Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner., Proc Natl Acad Sci U S A 2021 Oct; 118(40): .
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2021The invasive pathogen Yersinia pestis disrupts host blood vasculature to spread and provoke hemorrhages., PLoS Negl Trop Dis 2021 Oct; 15(10): e0009832.
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2021Cold Atmospheric Plasma Promotes Killing of Staphylococcus aureus by Macrophages., mSphere 2021 Jun; 6(3): e0021721.
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2021Internalization Assays for Listeria monocytogenes., Methods Mol. Biol. 2021 ; 2220: 189-200.
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