Timeline

Etienne Simon-Loriere

Head of Structure

09 Oct 2020

project

Study of immune crosstalk in COVID-19 COVIMUNE

03 Sep 2020

project

Host genetic susceptibility to Zika virus

03 Aug 2020

project

Pasteur International Center for Research on Emerging Infectious Diseases

01 Jul 2020

publication

Introductions and early spread of SARS-CoV-2 in France, 24 January to 23 March 2020.

17 Jan 2020

publication

Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b.

21 Jun 2019

publication

A Modified mRNA Vaccine Targeting Immunodominant NS Epitopes Protects Against Dengue Virus Infection in HLA Class I Transgenic Mice

06 Feb 2019

project

MICROTONE – Microbial and viral circulations among people and wild and domesticated animals in an ecotone, Democratic Republic of Congo

08 Oct 2018

patent

A Zika virus chimeric polyepitope comprising non-structural proteins and its use in immunogenic composition (EP 17 306553.3)

10 Jul 2018

publication

RIG-I Recognizes the 5′ Region of Dengue and Zika Virus Genomes.

01 Apr 2018

publication

Genetic Characterization of Enterovirus A71 Circulating in Africa.

15 Feb 2018

publication

Joint ancestry and association test indicate two distinct pathogenic pathways involved in classical dengue fever and dengue shock syndrome

19 Jan 2018

team

Evolutionary genomics of RNA viruses

05 Sep 2017

news

Cover page in Science Translational Medicine

30 Aug 2017

publication

Increased adaptive immune responses and proper feedback regulation protect against clinical dengue.

14 Jun 2017

publication

Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.

13 Apr 2017

publication

Autochthonous Japanese Encephalitis with Yellow Fever Coinfection in Africa

12 Apr 2017

publication

Virus genomes reveal factors that spread and sustained the Ebola epidemic

03 Nov 2016

publication

Human Adaptation of Ebola Virus during the West African Outbreak

01 Nov 2016

publication

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses.

27 Oct 2016

publication

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53

10 Aug 2016

publication

Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.

24 Jun 2015

publication

Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic

10 Jun 2015

publication

High Anti-Dengue Virus Activity of the OAS Gene Family Is Associated With Increased Severity of Dengue

11 May 2015

team

Functional Genetics of Infectious Diseases

24 Oct 2013

publication

Genetic diversity of the highly variable V1 region interferes with Human Immunodeficiency Virus type 1 envelope functionality

17 May 2013

publication

The effect of gene overlapping on the rate of RNA virus evolution

13 Mar 2013

publication

Gene duplication is infrequent in the recent evolutionary history of RNA viruses

23 Aug 2012

publication

Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation

15 Feb 2012

publication

Level of gene expression is a major determinant of protein evolution in the viral order Mononegavirales

04 Jul 2011

publication

Why do RNA viruses recombine?

01 Mar 2011

publication

RNA structures, genomic organization and selection of recombinant HIV

29 Sep 2010

publication

RNA structures facilitate recombination-mediated gene swapping in HIV-1

08 May 2009

publication

Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus

12 Sep 2008

publication

Identifying the important HIV-1 recombination breakpoints

04 Mar 2008

publication

Implications of recombination for HIV diversity

26 Sep 2006

publication

A little guide for advanced search:

Timeline

Study of immune crosstalk in COVID-19 COVIMUNE

Host genetic susceptibility to Zika virus

Pasteur International Center for Research on Emerging Infectious Diseases

Introductions and early spread of SARS-CoV-2 in France, 24 January to 23 March 2020.

Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b.

A Modified mRNA Vaccine Targeting Immunodominant NS Epitopes Protects Against Dengue Virus Infection in HLA Class I Transgenic Mice

MICROTONE – Microbial and viral circulations among people and wild and domesticated animals in an ecotone, Democratic Republic of Congo

A Zika virus chimeric polyepitope comprising non-structural proteins and its use in immunogenic composition (EP 17 306553.3)

RIG-I Recognizes the 5′ Region of Dengue and Zika Virus Genomes.

Genetic Characterization of Enterovirus A71 Circulating in Africa.

Joint ancestry and association test indicate two distinct pathogenic pathways involved in classical dengue fever and dengue shock syndrome

Evolutionary genomics of RNA viruses

Cover page in Science Translational Medicine

Increased adaptive immune responses and proper feedback regulation protect against clinical dengue.

Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.

Autochthonous Japanese Encephalitis with Yellow Fever Coinfection in Africa

Virus genomes reveal factors that spread and sustained the Ebola epidemic

Human Adaptation of Ebola Virus during the West African Outbreak

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses.

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53

Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.

Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic

High Anti-Dengue Virus Activity of the OAS Gene Family Is Associated With Increased Severity of Dengue

Functional Genetics of Infectious Diseases

Genetic diversity of the highly variable V1 region interferes with Human Immunodeficiency Virus type 1 envelope functionality

The effect of gene overlapping on the rate of RNA virus evolution

Gene duplication is infrequent in the recent evolutionary history of RNA viruses

Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation

Level of gene expression is a major determinant of protein evolution in the viral order Mononegavirales

Why do RNA viruses recombine?

RNA structures, genomic organization and selection of recombinant HIV

RNA structures facilitate recombination-mediated gene swapping in HIV-1

Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus

Identifying the important HIV-1 recombination breakpoints

Implications of recombination for HIV diversity

Sequence determinants of breakpoint location during HIV-1 intersubtype recombination